Activation of DNA damage response signaling by condensed chromatin (Q34713712)

4 August 2017

title

Activation of DNA damage response signaling by condensed chromatin (English)

1 reference

4 August 2017

0 references

4

Tom Misteli

1 reference

4 August 2017

2

Bharat Burman

1 reference

4 August 2017

Rebecca C Burgess

1

1 reference

4 August 2017

Michael J Kruhlak

series ordinal

3

1 reference

4 August 2017

publication date

20 November 2014

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4 August 2017

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4 August 2017

volume

9

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4 August 2017

issue

5

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4 August 2017

page(s)

1703-1717

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describes a project that uses

4 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4267891/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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7 July 2018

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7 July 2018

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Replication stress and chromatin context link ATM activation to a role in DNA replication.

7 July 2018

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KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling

7 July 2018

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7 July 2018

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7 July 2018

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SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response.

7 July 2018

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7 July 2018

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Prime, repair, restore: the active role of chromatin in the DNA damage response

7 July 2018

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BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair

7 July 2018

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Genome-wide profiles of H2AX and γ-H2AX differentiate endogenous and exogenous DNA damage hotspots in human cells

7 July 2018

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7 July 2018

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7 July 2018

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More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

7 July 2018

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Lac operator repeats generate a traceable fragile site in mammalian cells

7 July 2018

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KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.

7 July 2018

1 reference

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DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin

7 July 2018

1 reference

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HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair

7 July 2018

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Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair.

7 July 2018

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γH2A is a component of yeast heterochromatin required for telomere elongation.

7 July 2018

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The DNA Damage Response: Making It Safe to Play with Knives

7 July 2018

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Unbiased, genome-wide in vivo mapping of transcriptional regulatory elements reveals sex differences in chromatin structure associated with sex-specific liver gene expression

7 July 2018

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Fluorescence in situ hybridization on 3D cultures of tumor cells

7 July 2018

1 reference

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The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

7 July 2018

1 reference

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DNA damage signaling in response to double-strand breaks during mitosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Regulation of alternative splicing by histone modifications

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks

7 July 2018

1 reference

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Pseudo-DNA damage response in senescent cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

The emerging role of HP1 in the DNA damage response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Mobilization and recruitment of HP1: a bimodal response to DNA breakage.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Recruitment of heterochromatin protein 1 to DNA repair sites.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Heterochromatin protein 1 is recruited to various types of DNA damage.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Cellular mechanism for targeting heterochromatin formation in Drosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

ATM activation and signaling under hypoxic conditions.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Activation of the cellular DNA damage response in the absence of DNA lesions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

High-resolution mapping and characterization of open chromatin across the genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Global chromatin compaction limits the strength of the DNA damage response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Positional stability of single double-strand breaks in mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Heterochromatin revisited

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Activation of the chicken Ig-beta locus by the collaboration of scattered regulatory regions through changes in chromatin structure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Tumor formation via loss of a molecular motor protein.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Sequential phosphorylation of Ser-10 on histone H3 and ser-139 on histone H2AX and ATM activation during premature chromosome condensation: relationship to cell-cycle phase and apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

ATM is activated by default in mitosis, localizes at centrosomes and monitors mitotic spindle integrity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Phosphorylation of histone H2AX at M phase in human cells without DNA damage response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Clonogenic cell survival assay

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Active genes are tri-methylated at K4 of histone H3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Megabase chromatin domains involved in DNA double-strand breaks in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Detection of radiation-induced chromosome aberrations using fluorescence in situ hybridization in drug-induced premature chromosome condensations of tumour cell lines with different radiosensitivities

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Mechanisms of HP1-mediated gene silencing in Drosophila

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

Effects of tethering HP1 to euchromatic regions of the Drosophila genome.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267891

10.1016/J.CELREP.2014.10.060

26 October 2018

Identifiers

DOI

1 reference

release_4s27h7xgwjftfo4cygk6kocp7i

4 August 2017

Fatcat ID

1 reference

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mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4267891

1 reference

4 August 2017

1 reference