Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs (Q34756907)

4 August 2017

Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs (English)

1 reference

4 August 2017

1 reference

8

John J Miles

1 reference

4 August 2017

Michael D Crowther

3

0 references

Marco Donia

Marco Donia

7

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Andrew Godkin

Andrew J Godkin

11

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David K. Cole

David K Cole

10

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Per thor Straten

Per Thor Straten

13

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Mark Peakman

Mark Peakman

12

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Andrew K Sewell

Andrew K Sewell

15

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Inge Marie Svane

Inge Marie Svane

14

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Katie Tungatt

Katie Tungatt

1

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ORCID Public Data File 2021

author name string

Valentina Bianchi

2

1 reference

4 August 2017

Wendy E Powell

4

1 reference

4 August 2017

Andrea J Schauenburg

5

1 reference

4 August 2017

Andrew Trimby

6

1 reference

4 August 2017

Christopher J Holland

9

1 reference

4 August 2017

Garry Dolton

16

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4 August 2017

language of work or name

English

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publication date

1 December 2014

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4 August 2017

Journal of Immunology

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4 August 2017

194

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4 August 2017

1

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4 August 2017

463-474

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Creative Commons Attribution 3.0 Unported

4 August 2017

start time

5 November 2022

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April 2023 Public Data File from Crossref

copyright status

copyrighted

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cites work

Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells

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Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers

7 July 2018

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Different affinity windows for virus and cancer-specific T-cell receptors: implications for therapeutic strategies

7 July 2018

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Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

A single autoimmune T cell receptor recognizes more than a million different peptides

7 July 2018

1 reference

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Structural and biophysical determinants of αβ T-cell antigen recognition

7 July 2018

1 reference

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Detection of autoreactive CD4 T cells using major histocompatibility complex class II dextramers.

7 July 2018

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A novel tumor antigen derived from enhanced degradation of bax protein in human cancers.

7 July 2018

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Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

CD8 controls T cell cross-reactivity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

7 July 2018

1 reference

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Tricks with tetramers: how to get the most from multimeric peptide-MHC.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Class II major histocompatibility complex tetramer staining: progress, problems, and prospects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

The HLA A*0201-restricted hTERT(540-548) peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Human TCR-binding affinity is governed by MHC class restriction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

CD8 exerts differential effects on the deployment of cytotoxic T lymphocyte effector functions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Anti-coreceptor antibodies profoundly affect staining with peptide-MHC class I and class II tetramers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

High avidity antigen-specific CTL identified by CD8-independent tetramer staining

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

The use of chimeric A2K(b) tetramers to monitor HLA A2 immune responses in HLA A2 transgenic mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Tracking T cells with tetramers: new tales from new tools

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Phenotypic analysis of antigen-specific T lymphocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273996

9 December 2018

Identifiers

DOI

10.4049/JIMMUNOL.1401785

1 reference

4 August 2017

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4 August 2017

1 reference