More complicated than it looks: assembly of Notch pathway transcription complexes (Q34817647)

4 August 2017

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title

More complicated than it looks: assembly of Notch pathway transcription complexes (English)

1 reference

4 August 2017

R A Kovall

1

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PubMed ID

18758478

4 August 2017

language of work or name

English

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publication date

1 September 2008

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4 August 2017

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4 August 2017

27

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4 August 2017

38

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4 August 2017

5099-5109

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https://scigraph.springernature.com/pub.10.1038/onc.2008.223

4 August 2017

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cites work

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Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex.

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The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder

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Notch pathway: making sense of suppressor of hairless

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Notch signalling: a simple pathway becomes complex

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Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1

21 January 2018

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Mutational and energetic studies of Notch 1 transcription complexes

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Intrinsically unstructured proteins and their functions

21 January 2018

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High-resolution crystal structure of the human Notch 1 ankyrin domain

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RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex

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Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex

21 January 2018

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Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

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Notch signaling and inherited disease syndromes

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The multifaceted role of Notch in cardiac development and disease

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Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2

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Structure of an IkappaBalpha/NF-kappaB complex

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Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line

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Controls of germline stem cells, entry into meiosis, and the sperm/oocyte decision in Caenorhabditis elegans

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Notch and cancer: a double-edged sword

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Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA

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Inference of macromolecular assemblies from crystalline state

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Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5

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Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region

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Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins

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Quantitative dissection of the Notch:CSL interaction: insights into the Notch-mediated transcriptional switch.

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The crystal structure of a partial mouse Notch-1 ankyrin domain: repeats 4 through 7 preserve an ankyrin fold.

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Notch signaling in cancer.

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The ankyrin repeat as molecular architecture for protein recognition

21 January 2018

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Notch signaling: from the outside in

21 January 2018

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Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex

21 January 2018

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Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

21 January 2018

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LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway

21 January 2018

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Mastermind is a putative activator for Notch.

21 January 2018

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Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)

21 January 2018

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Regulation of lymphocyte development by Notch signaling

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p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

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Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.

21 January 2018

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MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

21 January 2018

1 reference

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Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex

21 January 2018

1 reference

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Structure and stability of the ankyrin domain of the Drosophila Notch receptor

21 January 2018

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Modulation of vascular gene expression by hypoxia

21 January 2018

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31 March 2020

Identifiers

DOI

10.1038/ONC.2008.223

1 reference

PubMed ID

18758478

Dimensions Publication ID

4 August 2017

0 references

1 reference

PubMed ID

18758478