Biology of Toll receptors: lessons from insects and mammals (Q35213805)

7 August 2017

1 reference

title

Biology of Toll receptors: lessons from insects and mammals (English)

1 reference

7 August 2017

Jean-Luc Imler

1

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PubMed ID

12960276

7 August 2017

Liangbiao Zheng

series ordinal

2

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7 August 2017

15 July 2003

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Journal of Leukocyte Biology

7 August 2017

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7 August 2017

75

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7 August 2017

18-26

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7 August 2017

1

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Phylogenetic perspectives in innate immunity

7 August 2017

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Pattern recognition receptors: doubling up for the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Cutting edge: the toll pathway is required for resistance to gram-positive bacterial infections in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The Drosophila genome sequence: implications for biology and medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Drosophila innate immunity: an evolutionary perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Drosophila immunity: paths and patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

How Drosophila combats microbial infection: a model to study innate immunity and host-pathogen interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Toll receptors in innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

IL-1 and IL-18 receptors, and their extended family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

TIR-X and TIR-NBS proteins: two new families related to disease resistance TIR-NBS-LRR proteins encoded in Arabidopsis and other plant genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The L6 gene for flax rust resistance is related to the Arabidopsis bacterial resistance gene RPS2 and the tobacco viral resistance gene N.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Independent evolution of Toll and related genes in insects and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The Drosophila Toll-9 activates a constitutive antimicrobial defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Characterization of three Toll-like genes from mosquito Aedes aegypti

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Characterization of four Toll related genes during development and immune responses in Anopheles gambiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Toll and Toll-like receptors in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Tissue and stage-specific expression of the Tolls in Drosophila embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

A conserved signaling pathway: the Drosophila toll-dorsal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Expression of a novel Toll-like gene spans the parasegment boundary and contributes to hedgehog function in the adult eye of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Induction of neuron-specific glycosylation by Tollo/Toll-8, a Drosophila Toll-like receptor expressed in non-neural cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Discrimination of bacterial lipoproteins by Toll-like receptor 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Recognition of gram-negative bacteria and endotoxin by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The extra domain A of fibronectin activates Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Proteolytic processing of the Drosophila Spätzle protein by easter generates a dimeric NGF-like molecule with ventralising activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

A family of proteins related to Spätzle, the toll receptor ligand, are encoded in the Drosophila genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Activation of Drosophila Toll during fungal infection by a blood serine protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Production of beta-defensins by human airway epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Toll-like receptors and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

A universal role for MyD88 in TLR/IL-1R-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Drosophila MyD88 is an adapter in the Toll signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

A heterotrimeric death domain complex in Toll signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

DmMyD88 controls dorsoventral patterning of the Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

IL-1 receptor-associated kinase modulates host responsiveness to endotoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

IRAK-M is a negative regulator of Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

NF-kappaB signaling pathways in mammalian and insect innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Double-stranded RNA signaling by Toll-like receptor 3 requires specific tyrosine residues in its cytoplasmic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Regulatory T cells in the control of immune pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

SMART: a web-based tool for the study of genetically mobile domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Toll-like Receptor 4 Polymorphisms and Atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

Genetically Resistant Mice Lacking MyD88-Adapter Protein Display a High Susceptibility to Leishmania major Infection Associated with a Polarized Th2 Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403160

21 January 2018

Identifiers

DOI

10.1189/JLB.0403160

1 reference

7 August 2017

1 reference

PubMed ID

12960276