Screening of DUB activity and specificity by MALDI-TOF mass spectrometry (Q35232335)

7 August 2017

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry (English)

1 reference

matrix-assisted laser desorption/ionization

7 August 2017

0 references

Nicola T Wood

8

0 references

Matthias Trost

Matthias Trost

13

0 references

Sharon M Kelly

Sharon M Kelly

7

0 references

Dario Alessi

Dario R Alessi

12

0 references

Maria Stella Ritorto

Maria Stella Ritorto

1

0 references

Satpal Virdee

Satpal Virdee

9

0 references

Nathanael Gray

10

Nathanael S Gray

1 reference

7 August 2017

4

Axel Knebel

1 reference

7 August 2017

6

Melanie Wightman

1 reference

7 August 2017

Richard Ewan

2

1 reference

7 August 2017

Ana B Perez-Oliva

3

1 reference

7 August 2017

Sara J Buhrlage

5

1 reference

7 August 2017

Nicholas A Morrice

11

1 reference

7 August 2017

language of work or name

English

0 references

publication date

27 August 2014

1 reference

7 August 2017

Nature Communications

1 reference

7 August 2017

5

1 reference

7 August 2017

4763

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

7 August 2017

start time

27 August 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms5763

0 references

cites work

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OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis

13 July 2018

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OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin

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The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases

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13 July 2018

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The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system

13 July 2018

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On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases

13 July 2018

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USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis

13 July 2018

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Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A.

13 July 2018

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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

13 July 2018

1 reference

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Profiling ubiquitin linkage specificities of deubiquitinating enzymes with branched ubiquitin isopeptide probes

13 July 2018

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Detection of ubiquitin-proteasome enzymatic activities in cells: application of activity-based probes to inhibitor development

13 July 2018

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Label-free quantitation of protein modifications by pseudo selected reaction monitoring with internal reference peptides

13 July 2018

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13 July 2018

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Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme

13 July 2018

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Precision of heavy-light peptide ratios measured by maldi-tof mass spectrometry.

13 July 2018

1 reference

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Phosphorylation-dependent activity of the deubiquitinase DUBA

13 July 2018

1 reference

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Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes

13 July 2018

1 reference

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Selective and cell-active inhibitors of the USP1/ UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells

13 July 2018

1 reference

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Mechanism, specificity and structure of the deubiquitinases

13 July 2018

1 reference

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Deubiquitinases in the regulation of NF-κB signaling

13 July 2018

1 reference

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Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin

13 July 2018

1 reference

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MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling

13 July 2018

1 reference

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Will the ubiquitin system furnish as many drug targets as protein kinases?

13 July 2018

1 reference

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Understanding the role of the Josephin domain in the PolyUb binding and cleavage properties of ataxin-3.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzymes

13 July 2018

1 reference

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Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase

13 July 2018

1 reference

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Degrasyn potentiates the antitumor effects of bortezomib in mantle cell lymphoma cells in vitro and in vivo: therapeutic implications

13 July 2018

1 reference

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Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

13 July 2018

1 reference

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Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells

13 July 2018

1 reference

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Breaking the chains: structure and function of the deubiquitinases

13 July 2018

1 reference

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Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

13 July 2018

1 reference

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Investigating the quantitative nature of MALDI-TOF MS.

13 July 2018

1 reference

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Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series

13 July 2018

1 reference

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Characterization of ubiquitin and ubiquitin-like-protein isopeptidase activities

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Structural Basis for Ubiquitin Recognition by the Otu1 Ovarian Tumor Domain Protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Targeting ubiquitin specific proteases for drug discovery

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Endocytosis: the DUB version

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

A genomic and functional inventory of deubiquitinating enzymes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Quantification of the A beta peptide in Alzheimer's plaques by laser dissection microscopy combined with mass spectrometry

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

AMSH is an endosome-associated ubiquitin isopeptidase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

USP6 (Tre2) fusion oncogenes in aneurysmal bone cyst

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Quantitative matrix-assisted laser desorption/ionization mass spectrometry for the determination of enzyme activities

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

The Dac-tag, an affinity tag based on penicillin-binding protein 5.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Bioluminescence assay platform for selective and sensitive detection of Ub/Ubl proteases

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

A substrate for deubiquitinating enzymes based on time-resolved fluorescence resonance energy transfer between terbium and yellow fluorescent protein.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147353

Targeted mass spectrometric approach for biomarker discovery and validation with nonglycosylated tryptic peptides from N-linked glycoproteins in human plasma

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS5763

Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo

21 January 2018

1 reference

12 December 2020

Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes

1 reference

12 December 2020

The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types

1 reference

12 December 2020

A sensitive fluorescence intensity assay for deubiquitinating proteases using ubiquitin-rhodamine110-glycine as substrate

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS5763

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference