NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights (Q35608150)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948299%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

review article

1 reference

title

NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights (English)

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13 February 2020

1

Sheryl M Gough

1 reference

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13 February 2020

Christopher I Slape

series ordinal

2

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13 February 2020

3

Peter D Aplan

1 reference

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13 February 2020

language of work or name

English

0 references

publication date

26 September 2011

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13 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948299%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

118

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13 February 2020

issue

24

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13 February 2020

page(s)

6247-6257

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Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice

13 February 2020

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Delineating domains and functions of NUP98 contributing to the leukemogenic activity of NUP98-HOX fusions

12 July 2018

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The reduced and altered activities of PAX5 are linked to the protein-protein interaction motif (coiled-coil domain) of the PAX5-PML fusion protein in t(9;15)-associated acute lymphocytic leukemia

12 July 2018

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Acute promyelocytic leukaemia: novel insights into the mechanisms of cure

12 July 2018

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Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations.

12 July 2018

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Role of the polycomb group proteins in hematopoietic stem cells

12 July 2018

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Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

12 July 2018

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Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms

12 July 2018

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Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1

12 July 2018

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Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia

12 July 2018

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The mobile FG nucleoporin Nup98 is a cofactor for Crm1-dependent protein export

12 July 2018

1 reference

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Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: role of a conserved helicase motif

12 July 2018

1 reference

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Regulation of differentiation by a PHD domain in the NUP98-PHF23 fusion protein

12 July 2018

1 reference

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Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes

12 July 2018

1 reference

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Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm

12 July 2018

1 reference

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MicroRNAs expression signatures are associated with lineage and survival in acute leukemias

12 July 2018

1 reference

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Non-coding RNAs: regulators of disease

12 July 2018

1 reference

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A NUP98-HOXD13 fusion gene impairs differentiation of B and T lymphocytes and leads to expansion of thymocytes with partial TCRB gene rearrangement.

12 July 2018

1 reference

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Chromosomes in leukemia and beyond: from irrelevant to central players

12 July 2018

1 reference

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MicroRNA and leukemia: tiny molecule, great function

12 July 2018

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Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

12 July 2018

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Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation

12 July 2018

1 reference

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Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.

12 July 2018

1 reference

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Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B Study

12 July 2018

1 reference

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Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell

12 July 2018

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HOX expression patterns identify a common signature for favorable AML.

12 July 2018

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NUP98-HOX translocations lead to myelodysplastic syndrome in mice and men

12 July 2018

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Impaired differentiation and apoptosis of hematopoietic precursors in a mouse model of myelodysplastic syndrome.

12 July 2018

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Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.

12 July 2018

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MicroRNA expression in cytogenetically normal acute myeloid leukemia

12 July 2018

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Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia

12 July 2018

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Imaging hematopoietic precursor division in real time

12 July 2018

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MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia

12 July 2018

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The role of CALM-AF10 gene fusion in acute leukemia

12 July 2018

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MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

12 July 2018

1 reference

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A novel gene, ANKRD28 on 3p25, is fused with NUP98 on 11p15 in a cryptic 3-way translocation of t(3;5;11)(p25;q35;p15) in an adult patient with myelodysplastic syndrome/acute myelogenous leukemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

MLL translocations, histone modifications and leukaemia stem-cell development

12 July 2018

1 reference

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Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.

12 July 2018

1 reference

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Hox genes in hematopoiesis and leukemogenesis.

12 July 2018

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Candidate genes for expansion and transformation of hematopoietic stem cells by NUP98-HOX fusion genes

12 July 2018

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The impact of translocations and gene fusions on cancer causation

12 July 2018

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Enforced expression of NUP98-HOXA9 in human CD34(+) cells enhances stem cell proliferation

12 July 2018

1 reference

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Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

12 July 2018

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The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia

12 July 2018

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NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells

12 July 2018

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Asymmetric and symmetric stem-cell divisions in development and cancer

12 July 2018

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NUP98 rearrangements in hematopoietic malignancies: a study of the Groupe Francophone de Cytogénétique Hématologique.

12 July 2018

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Identification of NUP98 abnormalities in acute leukemia: JARID1A (12p13) as a new partner gene

12 July 2018

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Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells

12 July 2018

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NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.

12 July 2018

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Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model

12 July 2018

1 reference

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NUP98-topoisomerase I acute myeloid leukemia-associated fusion gene has potent leukemogenic activities independent of an engineered catalytic site mutation

12 July 2018

1 reference

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Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1

12 July 2018

1 reference

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Cell death: critical control points

12 July 2018

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Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis

12 July 2018

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NSD1 is essential for early post-implantation development and has a catalytically active SET domain

12 July 2018

1 reference

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Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes

12 July 2018

1 reference

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Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13).

12 July 2018

1 reference

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The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98

12 July 2018

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12 July 2018

Focus on acute leukemias

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The chromosome translocation t(7;11)(p15;p15) in acute myeloid leukemia results in fusion of the NUP98 gene with a HOXA cluster gene, HOXA13, but not HOXA9

12 July 2018

1 reference

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A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9

12 July 2018

1 reference

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NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15).

12 July 2018

1 reference

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Nup98 is a mobile nucleoporin with transcription-dependent dynamics

12 July 2018

1 reference

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Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export

12 July 2018

1 reference

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Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15)

12 July 2018

1 reference

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The HOXD11 gene is fused to the NUP98 gene in acute myeloid leukemia with t(2;11)(q31;p15).

12 July 2018

1 reference

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Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion

12 July 2018

1 reference

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

12 July 2018

1 reference

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NUP98 gene rearrangements and the clonal evolution of chronic myelogenous leukemia

12 July 2018

1 reference

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NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice

12 July 2018

1 reference

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t(9;11)(p22;p15) in acute myeloid leukemia results in a fusion between NUP98 and the gene encoding transcriptional coactivators p52 and p75-lens epithelium-derived growth factor (LEDGF).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

MEIS1 and HOXA7 genes in human acute myeloid leukemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

12 July 2018

The Hallmarks of Cancer

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Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias

12 July 2018

1 reference

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The t(11;20)(p15;q11) chromosomal translocation associated with therapy-related myelodysplastic syndrome results in an NUP98-TOP1 fusion

12 July 2018

1 reference

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PBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

12 July 2018

1 reference

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Autoproteolysis in nucleoporin biogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

NUP98 is fused to PMX1 homeobox gene in human acute myelogenous leukemia with chromosome translocation t(1;11)(q23;p15).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells

12 July 2018

1 reference

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RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

A conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

A model for the mechanism of human topoisomerase I

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Nucleocytoplasmic transport: the last 200 nanometers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Stage-specific expression of polycomb group genes in human bone marrow cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Nucleocytoplasmic transport: signals, mechanisms and regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Hox genes in evolution: protein surfaces and paralog groups

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

The role of HOX homeobox genes in normal and leukemic hematopoiesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Protein import into the nucleus: an integrated view

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

A rational nomenclature for vertebrate homeobox (HOX) genes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Reconstituted nuclei depleted of a vertebrate GLFG nuclear pore protein, p97, import but are defective in nuclear growth and replication

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Identification of homeobox genes expressed in human haemopoietic progenitor cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Predicting coiled coils from protein sequences

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Homeobox genes and axial patterning

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

The role of microRNA-196a and microRNA-196b as ERG regulators in acute myeloid leukemia and acute T-lymphoblastic leukemia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

NUP98-MLL fusion in human acute myeloblastic leukemia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Acute myeloid leukemia bearing t(7;11)(p15;p15) is a distinct cytogenetic entity with poor outcome and a distinct mutation profile: comparative analysis of 493 adult patients.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Fusion of NUP98 and the SET binding protein 1 (SETBP1) gene in a paediatric acute T cell lymphoblastic leukaemia with t(11;18)(p15;q12).

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Retroviral integration site analysis identifies ICSBP as a collaborating tumor suppressor gene in NUP98-TOP1-induced leukemia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Trans-repressive effect of NUP98-PMX1 on PMX1-regulated c-FOS gene through recruitment of histone deacetylase 1 by FG repeats.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

NUP98 is fused to topoisomerase (DNA) IIbeta 180 kDa (TOP2B) in a patient with acute myeloid leukemia with a new t(3;11)(p24;p15).

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Characterization of 6q abnormalities in childhood acute myeloid leukemia and identification of a novel t(6;11)(q24.1;p15.5) resulting in a NUP98-C6orf80 fusion in a case of acute megakaryoblastic leukemia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Screening for NUP98 rearrangements in hematopoietic malignancies by fluorescence in situ hybridization.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

A new translocation t(9;11)(q34;p15) fuses NUP98 to a novel homeobox partner gene, PRRX2, in a therapy-related acute myeloid leukemia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome characterized by specific chromosomal abnormalities.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

NUP98 is fused to adducin 3 in a patient with T-cell acute lymphoblastic leukemia and myeloid markers, with a new translocation t(10;11)(q25;p15).

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

The (4;11)(q21;p15) translocation fuses the NUP98 and RAP1GDS1 genes and is recurrent in T-cell acute lymphocytic leukemia

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

NUP98–HMGB3: a novel oncogenic fusion

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236115

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

15 November 2018

1 reference

12 December 2020

Low frequency of rearrangements of the homeobox gene HOXA9/t(7;11) in adult acute myeloid leukemia

1 reference

12 December 2020

HoxA cluster is haploinsufficient for activity of hematopoietic stem and progenitor cells

1 reference

12 December 2020

High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes

1 reference

12 December 2020

A novel NUP98/RARG gene fusion in acute myeloid leukemia resembling acute promyelocytic leukemia

1 reference

12 December 2020

Recurrent coiled-coil motifs in NUP98 fusion partners provide a clue to leukemogenesis

1 reference

12 December 2020

Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny

1 reference

12 December 2020

Quantitative HOX expression in chromosomally defined subsets of acute myelogenous leukemia

1 reference

12 December 2020

Expression of NUP98/TOP1, but not of TOP1/NUP98, in a treatment-related myelodysplastic syndrome with t(10;20;11)(q24;q11;p15)

1 reference

12 December 2020

Novel NUP98-HOXC11 fusion gene resulted from a chromosomal break within exon 1 of HOXC11 in acute myeloid leukemia with t(11;12)(p15;q13)

1 reference

12 December 2020

Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1

1 reference

12 December 2020

Complex formation among the RNA export proteins Nup98, Rae1/Gle2, and TAP

1 reference

12 December 2020

Transplantable cell lines generated with NUP98-Hox fusion genes undergo leukemic progression by Meis1 independent of its binding to DNA

1 reference

12 December 2020

Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance

1 reference

12 December 2020

A novel NUP98-PHF23 fusion resulting from a cryptic translocation t(11;17)(p15;p13) in acute myeloid leukemia

1 reference

12 December 2020

A new fusion gene NUP98-IQCG identified in an acute T-lymphoid/myeloid leukemia with a t(3;11)(q29q13;p15)del(3)(q29) translocation

1 reference

12 December 2020

t(3;11)(q12;p15)/NUP98-LOC348801 fusion transcript in acute myeloid leukemia

1 reference

12 December 2020

Leukemogenic properties of NUP98-PMX1 are linked to NUP98 and homeodomain sequence functions but not to binding properties of PMX1 to serum response factor

1 reference

12 December 2020

10.1182/BLOOD-2011-07-328880

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948299%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948299%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

21948299

1 reference