Cytoplasmic tail adaptors of Alzheimer's amyloid-beta protein precursor (Q35913893)

11 August 2017

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title

Cytoplasmic tail adaptors of Alzheimer's amyloid-beta protein precursor (English)

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11 August 2017

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3

Masaaki Matsuoka

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11 August 2017

Masaoki Kawasumi

1

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11 August 2017

Shuji Matsuda

series ordinal

2

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11 August 2017

Ikuo Nishimoto

series ordinal

4

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11 August 2017

publication date

1 October 2004

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11 August 2017

published in

Molecular Neurobiology

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11 August 2017

volume

30

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11 August 2017

issue

2

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11 August 2017

page(s)

185-200

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A cytoplasmic inhibitor of the JNK signal transduction pathway

11 August 2017

cites work

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12 December 2020

Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

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12 December 2020

JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65

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12 December 2020

Reelin binds alpha3beta1 integrin and inhibits neuronal migration.

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12 December 2020

LET-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction

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12 December 2020

Antibody-regulated neurotoxic function of cell-surface beta-amyloid precursor protein

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12 December 2020

FE65 in Alzheimer's disease: neuronal distribution and association with neurofibrillary tangles

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12 December 2020

The Caenorhabditis elegans gene lin-10 is broadly expressed while required specifically for the determination of vulval cell fates

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12 December 2020

Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain

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12 December 2020

Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice

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12 December 2020

X11L2, a new member of the X11 protein family, interacts with Alzheimer's beta-amyloid precursor protein

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12 December 2020

Modulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains.

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12 December 2020

Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport

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12 December 2020

A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain

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12 December 2020

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

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12 December 2020

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

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12 December 2020

Amyloid precursor protein family-induced neuronal death is mediated by impairment of the neuroprotective calcium/calmodulin protein kinase IV-dependent signaling pathway.

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12 December 2020

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

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12 December 2020

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

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12 December 2020

Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms

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12 December 2020

Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc

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12 December 2020

LIN-10 is a shared component of the polarized protein localization pathways in neurons and epithelia

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12 December 2020

Fe65 and X11beta co-localize with and compete for binding to the amyloid precursor protein

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12 December 2020

Generation of the β-Amyloid Peptide and the Amyloid Precursor Protein C-terminal Fragment γ Are Potentiated by FE65L1

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12 December 2020

A FE65 polymorphism associated with risk of developing sporadic late-onset alzheimer's disease but not with Abeta loading in brains

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12 December 2020

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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12 December 2020

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12 December 2020

A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth

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12 December 2020

The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

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12 December 2020

X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion

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12 December 2020

The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids

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12 December 2020

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development

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12 December 2020

The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2

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12 December 2020

Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein

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12 December 2020

Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.

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12 December 2020

The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

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12 December 2020

Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).

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12 December 2020

Drosophila abl tyrosine kinase in embryonic CNS axons: a role in axonogenesis is revealed through dosage-sensitive interactions with disabled

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12 December 2020

Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3

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12 December 2020

Evidence against association of the FE65 gene (APBB1) intron 13 polymorphism in Alzheimer's patients

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12 December 2020

A mammalian scaffold complex that selectively mediates MAP kinase activation

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12 December 2020

Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules

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12 December 2020

Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neurons

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12 December 2020

Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.

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12 December 2020

Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain

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12 December 2020

Mints as adaptors. Direct binding to neurexins and recruitment of munc18

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12 December 2020

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

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12 December 2020

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

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12 December 2020

Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1.

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12 December 2020

The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells

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12 December 2020

A rat brain mRNA encoding a transcriptional activator homologous to the DNA binding domain of retroviral integrases

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12 December 2020

c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK

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12 December 2020

Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus

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12 December 2020

Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1.

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12 December 2020

Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins

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12 December 2020

Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

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12 December 2020

Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system

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12 December 2020

Molecular cloning of multiple splicing variants of JIP-1 preferentially expressed in brain

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12 December 2020

Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein

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12 December 2020

The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled

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12 December 2020

A phosphotyrosine interaction domain

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12 December 2020

Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition.

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12 December 2020

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth

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12 December 2020

The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2/LSF/LBP1

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12 December 2020

A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis

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12 December 2020

PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine

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12 December 2020

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

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12 December 2020

Isoform-specific knockout of FE65 leads to impaired learning and memory

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12 December 2020

Molecular analysis of the X11-mLin-2/CASK complex in brain

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12 December 2020

Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain.

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12 December 2020

The human FE65 gene: genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type

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12 December 2020

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor

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12 December 2020

The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.

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12 December 2020

Secreted Abeta does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein

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12 December 2020

A candidate molecular mechanism for the association of an intronic polymorphism of FE65 with resistance to very late onset dementia of the Alzheimer type

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12 December 2020

Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting

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12 December 2020

Genetic modulation of tau phosphorylation in the mouse.

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12 December 2020

beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

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12 December 2020

A risk for early-onset Alzheimer's disease associated with the APBB1 gene (FE65) intron 13 polymorphism

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12 December 2020

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

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12 December 2020

Neuronal position in the developing brain is regulated by mouse disabled-1

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12 December 2020

Synergistic effects of Munc18a and X11 proteins on amyloid precursor protein metabolism

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12 December 2020

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12 December 2020

The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene

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12 December 2020

Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein

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12 December 2020

The JIP group of mitogen-activated protein kinase scaffold proteins

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12 December 2020

Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation

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12 December 2020

Recombinations in individuals homozygous by descent localize the Friedreich ataxia locus in a cloned 450-kb interval.

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12 December 2020

Reelin is a ligand for lipoprotein receptors

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12 December 2020

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

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12 December 2020

Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid

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12 December 2020

Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells

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12 December 2020

The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation

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12 December 2020

Signal transduction by the JNK group of MAP kinases

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12 December 2020

Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein

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12 December 2020

Mints, Munc18-interacting proteins in synaptic vesicle exocytosis

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12 December 2020

Characterization of an amyloid precursor protein-binding protein Fe65L2 and its novel isoforms lacking phosphotyrosine-interaction domains

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12 December 2020

UNC-16, a JNK-signaling scaffold protein, regulates vesicle transport in C. elegans

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12 December 2020

Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein

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12 December 2020

Amyloid beta protein precursor is a mitogen

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12 December 2020

Demonstration by fluorescence resonance energy transfer of two sites of interaction between the low-density lipoprotein receptor-related protein and the amyloid precursor protein: role of the intracellular adapter protein Fe65.

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12 December 2020

Broadly altered expression of the mRNA isoforms of FE65, a facilitator of beta amyloidogenesis, in Alzheimer cerebellum and other brain regions.

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12 December 2020

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction

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12 December 2020

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

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12 December 2020

Proteins of the CNR family are multiple receptors for Reelin

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12 December 2020

p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity

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12 December 2020

PDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like protein

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12 December 2020

Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism

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12 December 2020

The amyloid precursor protein interacts with Go heterotrimeric protein within a cell compartment specialized in signal transduction

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12 December 2020

Genomic organization, fine-mapping, and expression of the human islet-brain 1 (IB1)/c-Jun-amino-terminal kinase interacting protein-1 (JIP-1) gene

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12 December 2020

Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease

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12 December 2020

Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase.

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12 December 2020

The intracellular domain of the low density lipoprotein receptor-related protein modulates transactivation mediated by amyloid precursor protein and Fe65.

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12 December 2020

Islet-brain1/JNK-interacting protein-1 is required for early embryogenesis in mice.

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12 December 2020

Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2

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12 December 2020

Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1

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12 December 2020

Requirement of the JIP1 scaffold protein for stress-induced JNK activation

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12 December 2020

Expression of the Fe65 adapter protein in adult and developing mouse brain.

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12 December 2020

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2

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12 December 2020

Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease

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12 December 2020

An alternative to SH2 domains for binding tyrosine-phosphorylated proteins

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12 December 2020

Identifiers

DOI

10.1385/MN:30:2:185

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Dimensions Publication ID

11 August 2017

1011423377

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