Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells (Q36016832)

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English	Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells	scientific article

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29 January 2020

Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells (English)

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29 January 2020

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skeletal muscle cell

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Charlotte J Green

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29 January 2020

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Sophie Turban

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29 January 2020

Clare Stretton

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29 January 2020

Olivier Drouin

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29 January 2020

Maria L Watson

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29 January 2020

Fiona Ross

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29 January 2020

Louise Lantier

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29 January 2020

Andre Marette

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29 January 2020

Harinder S Hundal

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17 April 2012

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29 January 2020

Journal of Biological Chemistry

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29 January 2020

20088-20099

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29 January 2020

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29 January 2020

AMPK: a nutrient and energy sensor that maintains energy homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

2 October 2017

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

1 reference

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2 October 2017

Metformin activates AMP kinase through inhibition of AMP deaminase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

2 October 2017

Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

2 October 2017

Genetic downregulation of AMPK-alpha isoforms uncovers the mechanism by which metformin decreases FA uptake and oxidation in skeletal muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

2 October 2017

Metformin blocks migration and invasion of tumour cells by inhibition of matrix metalloproteinase-9 activation through a calcium and protein kinase Calpha-dependent pathway: phorbol-12-myristate-13-acetate-induced/extracellular signal-regulated [...]

1 reference

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2 October 2017

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

1 reference

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2 October 2017

Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation

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2 October 2017

Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells

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2 October 2017

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

1 reference

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2 October 2017

Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome

1 reference

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2 October 2017

Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms

1 reference

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2 October 2017

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

1 reference

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2 October 2017

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

1 reference

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2 October 2017

Inhibition of inducible nitric-oxide synthase by activators of AMP-activated protein kinase: a new mechanism of action of insulin-sensitizing drugs

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2 October 2017

Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.

1 reference

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2 October 2017

Role of Akt/protein kinase B in metabolism.

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2 October 2017

Metformin enhances insulin signalling in insulin-dependent and-independent pathways in insulin resistant muscle cells

1 reference

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2 October 2017

The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

2 October 2017

Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

2 October 2017

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

1 reference

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2 October 2017

Role of AMP-activated protein kinase in mechanism of metformin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

2 October 2017

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

1 reference

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2 October 2017

Protein kinase B (PKB/Akt)--a key regulator of glucose transport?

1 reference

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2 October 2017

Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner

1 reference

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2 October 2017

Mechanism by which metformin reduces glucose production in type 2 diabetes

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2 October 2017

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

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2 October 2017

Analysis of the role of the AMP-activated protein kinase in the response to cellular stress.

1 reference

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2 October 2017

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

1 reference

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2 October 2017

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

1 reference

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2 October 2017

Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress. Evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated protein kinase signaling pathways

1 reference

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2 October 2017

5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

2 October 2017

Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells

1 reference

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2 October 2017

Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport

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2 October 2017

The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase-1beta (Rsk-2) and p70 S6 kinase.

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2 October 2017

Metabolic effects of metformin in non-insulin-dependent diabetes mellitus

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2 October 2017

Mechanism of Action of Metformin: Insulin Receptor and Postreceptor Effects in Vitro and in Vivo*

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2 October 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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2 October 2017

Cellular depletion of atypical PKC{lambda} is associated with enhanced insulin sensitivity and glucose uptake in L6 rat skeletal muscle cells.

1 reference

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11 July 2018

Coordinated maintenance of muscle cell size control by AMP-activated protein kinase

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11 July 2018

Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

11 July 2018

Metformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

11 July 2018

Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphatases and selective detection of signaling lipids in cell and tissue extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

11 July 2018

Effects of metformin on tyrosine kinase activity, glucose transport, and intracellular calcium in rat vascular smooth muscle

1 reference

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11 July 2018

Multiple roles of phosphatidylinositol 3-kinase in regulation of glucose transport, amino acid transport, and glucose transporters in L6 skeletal muscle cells

1 reference

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11 July 2018

Stimulation of hexose transport by metformin in L6 muscle cells in culture

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11 July 2018

Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells

1 reference

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11 July 2018

Long-term metformin treatment stimulates cardiomyocyte glucose transport through an AMP-activated protein kinase-dependent reduction in GLUT4 endocytosis.

1 reference

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23 September 2018

Muscle cell depolarization induces a gain in surface GLUT4 via reduced endocytosis independently of AMPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

23 September 2018

Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3,4,5-(PO4)3 in muscle of diabetic subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370192

23 September 2018

Insulin signalling downstream of protein kinase B is potentiated by 5'AMP-activated protein kinase in rat hearts in vivo.

1 reference

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23 September 2018

Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species

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23 September 2018

Metformin (Glucophage) inhibits tyrosine phosphatase activity to stimulate the insulin receptor tyrosine kinase.

1 reference

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23 September 2018

Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

1 reference

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23 September 2018

Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase

1 reference

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23 September 2018

Depolarization of the liver cell membrane by metformin

1 reference

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23 September 2018

Dissociation of 5' AMP-activated protein kinase activation and glucose uptake stimulation by mitochondrial uncoupling and hyperosmolar stress: differential sensitivities to intracellular Ca2+ and protein kinase C inhibition

1 reference

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23 September 2018

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

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21 January 2018

Prevention of dexamethasone-induced insulin resistance by metformin

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12 December 2020

based on heuristic

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Effect of AMPK activation on muscle glucose metabolism in conscious rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22511782

12 December 2020

based on heuristic

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5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22511782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metformin treatment enhances insulin-stimulated glucose transport in skeletal muscle of Sprague-Dawley rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22511782

12 December 2020

based on heuristic

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The blooming of the French lilac

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1172/JCI14178

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10.1074/JBC.M111.330746

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30 July 2022

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30 July 2022

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30 July 2022

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