Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling (Q36185627)

12 August 2017

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title

Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling (English)

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12 August 2017

author name string

Constantine S Mitsiades

series ordinal

1

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12 August 2017

Nicholas Mitsiades

series ordinal

2

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12 August 2017

publication date

1 June 2005

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Expert Review of Anticancer Therapy

12 August 2017

published in

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12 August 2017

volume

5

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12 August 2017

issue

3

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12 August 2017

page(s)

487-499

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

12 August 2017

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21 January 2018

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Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinomas

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Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor I receptor

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The insulin-like growth factor I receptor gene is the target for the 15q26 amplicon in breast cancer.

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts

21 January 2018

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Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871.

21 January 2018

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Insulin-like growth factors modulate the growth inhibitory effects of retinoic acid on MCF-7 breast cancer cells

21 January 2018

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ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: evidence for enhanced interactions with the insulin-like growth factor-I receptor

21 January 2018

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Insulinlike growth factor I: a potent mitogen for human osteogenic sarcoma

21 January 2018

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21 January 2018

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21 January 2018

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Effect of endocrine therapy on growth of T61 human breast cancer xenografts is directly correlated to a specific down-regulation of insulin-like growth factor II (IGF-II).

21 January 2018

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Simultaneous blockade of both the epidermal growth factor receptor and the insulin-like growth factor receptor signaling pathways in cancer cells with a fully human recombinant bispecific antibody.

21 January 2018

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Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth

21 January 2018

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In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase

21 January 2018

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Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth.

21 January 2018

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Substrate competitive inhibitors of IGF-1 receptor kinase

21 January 2018

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Development of new insulin-like growth factor-1 receptor kinase inhibitors using catechol mimics

21 January 2018

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Recombinant insulin-like growth factor binding protein-1 inhibits IGF-I, serum, and estrogen-dependent growth of MCF-7 human breast cancer cells.

21 January 2018

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Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism

21 January 2018

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Insulin-like growth factor-binding protein 3 induces caspase-dependent apoptosis through a death receptor-mediated pathway in MCF-7 human breast cancer cells.

21 January 2018

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Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence

21 January 2018

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Polyethylene glycol conjugated insulin-like growth factor binding protein-1 (IGFBP-1) inhibits growth of breast cancer in athymic mice

21 January 2018

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Antitumor activity of the growth hormone receptor antagonist pegvisomant against human meningiomas in nude mice

21 January 2018

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Combination of somatostatin analog, dexamethasone, and standard androgen ablation therapy in stage D3 prostate cancer patients with bone metastases

21 January 2018

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The role of the insulin-like growth factor-I receptor in cancer

21 January 2018

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Functional Polymorphism in the Parental Imprinting of the Human IGF2R Gene

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/14737140.5.3.487

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