Development of beta-amyloid-induced neurodegeneration in Alzheimer's disease and novel neuroprotective strategies. (Q36329164)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16323560%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

review article

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title

Development of beta-amyloid-induced neurodegeneration in Alzheimer's disease and novel neuroprotective strategies (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16323560%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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1

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9 January 2020

author name string

Christian Hölscher

series ordinal

1

1 reference

13 August 2017

1 January 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16323560%20AND%20SRC:MED&resulttype=core&format=json

Reviews in the Neurosciences

9 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16323560%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

16

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9 January 2020

issue

3

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9 January 2020

page(s)

181-212

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Neuronal membrane cholesterol loss enhances amyloid peptide generation

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Memory and long-term potentiation (LTP) dissociated: normal spatial memory despite CA1 LTP elimination with Kv1.4 antisense

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Neurotrophic and neuroprotective effects of hAPP in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val→Ile mutation in the amyloid precursor protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Reactive oxygen species and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Role of neurotransmission in the regulation of amyloid beta-protein precursor processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Glucose-dependent insulinotropic polypeptide is expressed in adult hippocampus and induces progenitor cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Neuroprotective effects of the antioxidant LY231617 and NO synthase inhibitors in global cerebral ischaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: specific localization in affected neurones and axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Decay characteristics of HIV-1-infected compartments during combination therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

A new Alzheimer's disease interventive strategy: GLP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Ion channel hypothesis for Alzheimer amyloid peptide neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Cholesterol efflux as a critical component of Alzheimer's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Pw1/Peg3 is a potential cell death mediator and cooperates with Siah1a in p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Transforming growth factors-beta protect primary rat hippocampal neuronal cultures from degeneration induced by beta-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Behavioural and histopathological analyses of ibuprofen treatment on the effect of aggregated Abeta(1-42) injections in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

An Alzheimer's disease hypothesis based on transcriptional dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Electrophysiological studies on the hippocampus and prefrontal cortex assessing the effects of amyloidosis in amyloid precursor protein 23 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Intracerebral beta-amyloid(25-35) produces tissue damage: is it neurotoxic?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

APP gene family. Alternative splicing generates functionally related isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Ca2+/calmodulin-regulated nitric oxide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

New Alzheimer's therapy suggested.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Differential contribution of the three Aph1 genes to gamma-secretase activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Activation of microglial cells by PrP and beta-amyloid fragments raises intracellular calcium through L-type voltage sensitive calcium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Amyloid beta protein (25-35) stimulation of phospholipases A, C and D activities of LA-N-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

A role for the beta-amyloid precursor protein in memory?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

The role of heparan sulfate proteoglycans in the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Failure of beta-amyloid protein fragment 25-35 to cause hippocampal damage in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Single intracerebroventricular administration of amyloid-beta (25-35) peptide induces impairment in short-term rather than long-term memory in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Ibuprofen: effect on inducible nitric oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Superoxide free radical and intracellular calcium mediate A beta(1-42) induced endothelial toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Roles of MAPKKK ASK1 in stress-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

beta-Amyloid-mediated vasoactivity and vascular endothelial damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

21 January 2018

Putting the rap on Akt.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

nNOS expressing neurons in the entorhinal cortex and hippocampus are affected in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Maturational regulation and regional induction of cyclooxygenase-2 in rat brain: implications for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Hippocampal synaptic plasticity and glutamate receptor regulation: influences of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Age-dependent cognitive decline in the APP23 model precedes amyloid deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Insulin-like growth factor-I, cognition and brain aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Amyloid, Presenilins, and Alzheimer’s Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Deciphering the molecular basis of memory failure in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Alzheimer's disease: diagnosis and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

A fluid connection: cholesterol and Abeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Activation of NR1a/NR2B receptors by soluble factors from APP-stimulated monocyte-derived macrophages: implications for the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Cerebral amyloid angiopathy and gene polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Mice deficient for the amyloid precursor protein gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Activation of Multiple Metabotropic Glutamate Receptor Subtypes Prevents NMDA-induced Excitotoxicity in Rat Hippocampal Slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2005.16.3.181

Beta-amyloid induced reduction in synaptic transmission is reversed by inhibitors of nitric oxide synthase

21 January 2018

1 reference

3 January 2024

https://opencitations.net/index/api/v1/citations/10.1097/00001756-199804200-00052

Identifiers

DOI

10.1515/REVNEURO.2005.16.3.181

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16323560%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference