Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells (Q36377759)

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17 February 2020

title

Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells (English)

1 reference

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17 February 2020

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7

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17 February 2020

6

Andrew M Donson

1 reference

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17 February 2020

author name string

Susan L Whiteway

1

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17 February 2020

Peter S Harris

2

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17 February 2020

Sujatha Venkataraman

3

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17 February 2020

Irina Alimova

4

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17 February 2020

Diane K Birks

5

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17 February 2020

Rajeev Vibhakar

8

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17 February 2020

publication date

9 November 2012

1 reference

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Journal of Neuro-Oncology

17 February 2020

published in

1 reference

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17 February 2020

volume

111

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17 February 2020

page(s)

113-121

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17 February 2020

issue

2

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https://scigraph.springernature.com/pub.10.1007/s11060-012-1000-7

17 February 2020

exact match

0 references

cites work

The clinical implications of medulloblastoma subgroups

1 reference

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Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model

30 September 2017

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Off-target function of the Sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide-dependent neutral sphingomyelinase 2/ceramide induction

30 September 2017

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Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma

30 September 2017

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Molecular subgroups of medulloblastoma: the current consensus

30 September 2017

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Cyclin D as a therapeutic target in cancer

30 September 2017

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Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1).

30 September 2017

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Cdk6-dependent regulation of G(1) length controls adult neurogenesis

30 September 2017

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Medulloblastoma comprises four distinct molecular variants

30 September 2017

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MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence

30 September 2017

1 reference

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miR-129 regulates cell proliferation by downregulating Cdk6 expression

30 September 2017

1 reference

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Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts

30 September 2017

1 reference

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Unique molecular characteristics of pediatric myxopapillary ependymoma

30 September 2017

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The potential impact of tumour biology on improved clinical practice for medulloblastoma: progress towards biologically driven clinical trials

30 September 2017

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Cell cycle kinases as therapeutic targets for cancer

30 September 2017

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Cell cycle, CDKs and cancer: a changing paradigm

30 September 2017

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Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma

30 September 2017

1 reference

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Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation

30 September 2017

1 reference

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Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma

30 September 2017

1 reference

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Beyond the cell cycle: a new role for Cdk6 in differentiation

30 September 2017

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Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6.

30 September 2017

1 reference

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Expression of cyclin-dependent kinase 6, but not cyclin-dependent kinase 4, alters morphology of cultured mouse astrocytes

30 September 2017

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Medulloblastoma: clinical and biologic aspects

30 September 2017

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Dynamic monitoring of cytotoxicity on microelectronic sensors

30 September 2017

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A novel therapeutic combination using PD 0332991 and bortezomib: study in the 5T33MM myeloma model.

28 June 2018

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Progress and challenges in childhood brain tumors.

21 September 2018

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21 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23138228

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11060-012-1000-7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23138228%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23138228%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference