Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse. (Q36464551)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17662610%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse (English)

1 reference

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2 January 2020

4

1 reference

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2 January 2020

5

Elliott J Mufson

1 reference

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2 January 2020

1

Sylvia E Perez

1 reference

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2 January 2020

author name string

Saleem Dar

series ordinal

2

1 reference

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2 January 2020

Milos D Ikonomovic

series ordinal

3

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2 January 2020

publication date

27 June 2007

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2 January 2020

published in

Neurobiology of Disease

1 reference

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2 January 2020

volume

28

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2 January 2020

issue

1

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2 January 2020

page(s)

3-15

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Induction of autophagy in axonal dystrophy and degeneration

2 January 2020

cites work

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30 September 2017

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Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

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30 September 2017

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30 September 2017

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Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis

30 September 2017

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30 September 2017

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Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

30 September 2017

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beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology

30 September 2017

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Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease

30 September 2017

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

30 September 2017

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Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

30 September 2017

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Mechanisms of neuronal degeneration in Alzheimer's disease

30 September 2017

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Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowth

30 September 2017

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New stereological methods for counting neurons

30 September 2017

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Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis

30 September 2017

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Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

30 September 2017

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The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis.

30 September 2017

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Alzheimer's disease and related dementias: selective involvement of specific neuronal systems.

30 September 2017

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Selective loss of cholinergic neurons in the ventral striatum of patients with Alzheimer disease

30 September 2017

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Hypothesis: interference with axonal transport of neurofilament as a common pathogenetic mechanism in certain diseases of the central nervous system

30 September 2017

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Axonal and transneuronal transport in the transmission of neurological disease: potential role in system degenerations, including Alzheimer's disease

30 September 2017

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Diffuse plaques do not accentuate synapse loss in Alzheimer's disease

30 September 2017

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30 September 2017

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Neurotransmitter-related enzymes in senile dementia of the alzheimer type

30 September 2017

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alpha7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in beta-amyloid infused rats

30 September 2017

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Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

28 June 2018

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Abeta1-42 promotes cholinergic sprouting in patients with AD and Lewy body variant of AD.

28 June 2018

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Cholinergic neuropathology in a mouse model of Alzheimer's disease

28 June 2018

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Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis.

28 June 2018

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Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

28 June 2018

1 reference

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Survival and plasticity of basal forebrain cholinergic systems in mice transgenic for presenilin-1 and amyloid precursor protein mutant genes

28 June 2018

1 reference

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Mutant genes in familial Alzheimer's disease and transgenic models

28 June 2018

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Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

28 June 2018

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A role for TrkA during maturation of striatal and basal forebrain cholinergic neurons in vivo.

28 June 2018

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Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease

28 June 2018

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Co-localization of vasoactive intestinal polypeptide, gamma-aminobutyric acid and choline acetyltransferase in neocortical interneurons of the adult rat.

28 June 2018

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Choline acetyltransferase mRNA expression in the striatal neurons of patients with Alzheimer's disease

28 June 2018

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Cholinergic innervation of the amygdaloid complex in the human brain and its alterations in old age and Alzheimer's disease

28 June 2018

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TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin

28 June 2018

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Nerve growth factor in Alzheimerʼs disease: defective retrograde transport to nucleus basalis

28 June 2018

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Human striatum: Chemoarchitecture of the caudate nucleus, putamen and ventral striatum in health and Alzheimer's disease

28 June 2018

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Choline acetyltransferase-immunoreactive neurons intrinsic to rodent cortex and distinction from acetylcholinesterase-positive neurons

28 June 2018

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Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6).

28 June 2018

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Laminar organization of cholinergic circuits in human frontal cortex in Alzheimer's disease and aging

28 June 2018

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Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease.

28 June 2018

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Observations on choline acetyltransferase containing structures in the CD-1 mouse brain

28 June 2018

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Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrain

28 June 2018

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Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: colocalization with cholinergic neurons

28 June 2018

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Patterns of aberrant sprouting in Alzheimer's disease

28 June 2018

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The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease

28 June 2018

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Modified Bielschowsky stain and immunohistochemical studies on striatal plaques in Alzheimer's disease.

28 June 2018

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Alzheimer's disease: striatal amyloid deposits and neurofibrillary changes.

28 June 2018

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28 June 2018

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A rapid radiochemical method for the determination of choline acetyltransferase

28 June 2018

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Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

28 June 2018

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Selective loss of central cholinergic neurons in Alzheimer's disease

28 June 2018

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Cholinergic systems in mammalian brain identified with antibodies against choline acetyltransferase.

28 June 2018

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Superior frontal cortex cholinergic axon density in mild cognitive impairment and early Alzheimer disease.

21 September 2018

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Impairment of muscarinic transmission in transgenic APPswe/PS1dE9 mice

21 September 2018

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Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1xAPP transgenic model of Alzheimer's disease

21 September 2018

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The amyloid pathology progresses in a neurotransmitter-specific manner

21 September 2018

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Nigrostriatal dysfunction in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 transgenic mice.

21 September 2018

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Selective cholinergic denervation, independent from oxidative stress, in a mouse model of Alzheimer's disease

21 September 2018

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Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities

21 September 2018

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Cortical GABA interneurons in neurovascular coupling: relays for subcortical vasoactive pathways.

21 September 2018

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Presenilin mutations in familial Alzheimer disease and transgenic mouse models accelerate neuronal lysosomal pathology.

21 September 2018

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Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology

21 September 2018

1 reference

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Amyloid-beta antibody treatment leads to rapid normalization of plaque-induced neuritic alterations.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

The impact of Aβ-plaques on cortical cholinergic and non-cholinergic presynaptic boutons in alzheimer's disease-like transgenic mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

Degeneration of beta-amyloid-associated cholinergic structures in transgenic APP SW mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

In vivo multiphoton imaging of a transgenic mouse model of Alzheimer disease reveals marked thioflavine-S-associated alterations in neurite trajectories

21 September 2018

1 reference

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Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.

21 September 2018

1 reference

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Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

21 September 2018

1 reference

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Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice

21 September 2018

1 reference

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Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

21 September 2018

1 reference

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Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

Dopamine transporter-immunoreactive neurons decrease with age in the human substantia nigra

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

The distribution of amyloid beta protein deposition in the corpus striatum of patients with Alzheimer's disease

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

Systematic regional variations in the loss of cortical cholinergic fibers in Alzheimer's disease.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

Human striatum: the distribution of neurofibrillary tangles in Alzheimer's disease

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

Acetylcholine and choline levels in post-mortem human brain tissue: preliminary observations in Alzheimer's disease.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

Alzheimer's disease. Correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

Neuritic plaques in senile dementia of Alzheimer type: a Golgi analysis in the hippocampal region

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

Correlative decrease of large neurons in the neostriatum and basal nucleus of Meynert in Alzheimer's disease

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245889

A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES

21 September 2018

1 reference

12 December 2020

A vector for expressing foreign genes in the brains and hearts of transgenic mice

1 reference

12 December 2020

Abeta associated neuropil changes: correlation with neuronal loss and dementia

1 reference

12 December 2020

Morphology and distribution of Alzheimer neuritic (senile) and amyloid plaques in striatum and diencephalon

1 reference

12 December 2020

10.1016/J.NBD.2007.06.015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17662610%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17662610%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PubMed publication ID

17662610

1 reference