Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration (Q36483438)

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English	Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

14 August 2017

Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration (English)

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Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Hailiang Hu

1

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Europe PubMed Central

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14 August 2017

Marc Milstein

2

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Europe PubMed Central

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14 August 2017

Joanne M Bliss

3

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Europe PubMed Central

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14 August 2017

Minh Thai

4

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Europe PubMed Central

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14 August 2017

Gautam Malhotra

5

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Europe PubMed Central

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14 August 2017

Lucia C Huynh

6

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14 August 2017

John Colicelli

7

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14 August 2017

language of work or name

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publication date

26 December 2007

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14 August 2017

Molecular and Cellular Biology

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14 August 2017

28

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14 August 2017

5

1 reference

Europe PubMed Central

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14 August 2017

1573-1583

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

RIN1 is a breast tumor suppressor gene

1 reference

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Defective TGF-beta signaling sensitizes human cancer cells to rapamycin

1 reference

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Erbin inhibits transforming growth factor beta signaling through a novel Smad-interacting domain

1 reference

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Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.

1 reference

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Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation

1 reference

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Rin1 interacts with signal-transducing adaptor molecule (STAM) and mediates epidermal growth factor receptor trafficking and degradation

1 reference

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Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation.

1 reference

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Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-beta signaling

1 reference

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1 reference

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Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin

1 reference

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1 reference

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1 reference

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Signaling and endocytosis: a team effort for cell migration

1 reference

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1 reference

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RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration

1 reference

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1 reference

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1 reference

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The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells

1 reference

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1 reference

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Cytoplasmic PML function in TGF-beta signalling

1 reference

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Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5.

1 reference

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Met, metastasis, motility and more

1 reference

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TLP, a novel modulator of TGF-beta signaling, has opposite effects on Smad2- and Smad3-dependent signaling

1 reference

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A multigenic program mediating breast cancer metastasis to bone

1 reference

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Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

1 reference

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The SRC homology 2 domain of Rin1 mediates its binding to the epidermal growth factor receptor and regulates receptor endocytosis

1 reference

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1 reference

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The RAS effector RIN1 modulates the formation of aversive memories

1 reference

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1 reference

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1 reference

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1 reference

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The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.

1 reference

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Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

28 June 2018

Structure-function relationship of the small GTPase rab5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

28 June 2018

Differentiation plasticity regulated by TGF-beta family proteins in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258770

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18160707

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10.1128/MCB.01087-07

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Europe PubMed Central

PMC publication ID

14 August 2017

release_q5jocs6pn5g2vghxxez55kacha

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https://api.fatcat.wiki/v0/release/q5jocs6pn5g2vghxxez55kacha

24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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