PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications. (Q36549536)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26838266%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications (English)

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7 March 2020

3

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7 March 2020

Greg M Kowalski

4

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7 March 2020

Clinton R. Bruce

5

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7 March 2020

author name string

G I Lancaster

1

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7 March 2020

H L Kammoun

2

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7 March 2020

M A Febbraio

6

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7 March 2020

language of work or name

English

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publication date

3 February 2016

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7 March 2020

published in

Nature Communications

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7 March 2020

volume

7

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7 March 2020

page(s)

10626

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Creative Commons Attribution 4.0 International

7 March 2020

copyright license

start time

3 February 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/ncomms10626

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cites work

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Regulation of actin dynamics by protein kinase R control of gelsolin enforces basal innate immune defense

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Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation

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Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

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Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis

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Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

30 September 2017

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Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells

30 September 2017

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Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

30 September 2017

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30 September 2017

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Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity

30 September 2017

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30 September 2017

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A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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28 June 2018

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Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity

28 June 2018

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Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

28 June 2018

1 reference

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NK cells link obesity-induced adipose stress to inflammation and insulin resistance.

28 June 2018

1 reference

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Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice.

21 September 2018

1 reference

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Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB.

21 September 2018

1 reference

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The sickness behaviour and CNS inflammatory mediator profile induced by systemic challenge of mice with synthetic double-stranded RNA (poly I:C).

21 September 2018

1 reference

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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

21 September 2018

1 reference

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21 September 2018

Identifiers

DOI

10.1038/NCOMMS10626

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26838266%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26838266%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26838266%20AND%20SRC:MED&resulttype=core&format=json