Novel aspects of prions, their receptor molecules, and innovative approaches for TSE therapy (Q36676179)

15 August 2017

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title

Novel aspects of prions, their receptor molecules, and innovative approaches for TSE therapy (English)

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15 August 2017

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Karen Vana

1

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15 August 2017

Chantal Zuber

series ordinal

2

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15 August 2017

Daphne Nikles

series ordinal

3

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15 August 2017

Stefan Weiss

series ordinal

4

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15 August 2017

publication date

7 December 2006

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Cellular and Molecular Neurobiology

15 August 2017

published in

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15 August 2017

volume

27

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15 August 2017

issue

1

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15 August 2017

page(s)

107-128

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MS-8209, a new amphotericin B derivative, provides enhanced efficacy in delaying hamster scrapie

15 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

The 67-kDa laminin receptor originated from a ribosomal protein that acquired a dual function during evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

Functional implication of cellular prion protein in antigen-driven interactions between T cells and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

Encephalopathy of mink: II. Experimental and natural transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

Normal cellular prion protein is preferentially expressed on subpopulations of murine hemopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

Bovine prion is endocytosed by human enterocytes via the 37 kDa/67 kDa laminin receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

Cellular prion protein status in sheep: tissue-specific biochemical signatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

A subtype of sporadic prion disease mimicking fatal familial insomnia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

Characterization and application of a novel RNA aptamer against the mouse prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

A novel progressive spongiform encephalopathy in cattle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

CHRONIC WASTING DISEASE OF CAPTIVE MULE DEER: A SPONGIFORM ENCEPHALOPATHY

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

Prion protein expression in muscle cells and toxicity of a prion protein fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-006-9121-1

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

21 January 2018

1 reference

12 December 2020

Altered circadian activity rhythms and sleep in mice devoid of prion protein

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12 December 2020

Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry

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12 December 2020

Anchorless prion protein results in infectious amyloid disease without clinical scrapie

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12 December 2020

Structural clues to prion replication

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12 December 2020

Molecular biology and genetics of prion diseases

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12 December 2020

Lymphoid signal transduction mechanisms linked to cellular prion protein

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12 December 2020

The chemistry of scrapie infection: implications of the 'ice 9' metaphor

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12 December 2020

Mice devoid of PrP are resistant to scrapie

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12 December 2020

Prions and prion proteins

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12 December 2020

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

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12 December 2020

Prion protein is a component of the multimolecular signaling complex involved in T cell activation.

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12 December 2020

Formation of the 67-kDa laminin receptor by acylation of the precursor

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12 December 2020

Spongiform encephalopathy in an arabian oryx (Oryx leucoryx) and a greater kudu (Tragelaphus strepsiceros)

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12 December 2020

The normal cellular form of prion protein modulates T cell responses

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12 December 2020

Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein.

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12 December 2020

Two dimensional VOPBA reveals laminin receptor (LAMR1) interaction with dengue virus serotypes 1, 2 and 3

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12 December 2020

Chemoprophylaxis of scrapie in mice

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12 December 2020

Overexpression of PrPc triggers caspase 3 activation: potentiation by proteasome inhibitors and blockade by anti-PrP antibodies

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12 December 2020

Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis

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12 December 2020

Analysis of PrPc mRNA by in situ hybridization in brain, placenta, uterus and testis of rats

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12 December 2020

Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

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12 December 2020

Amphotericin B delays the incubation period of scrapie in intracerebrally inoculated hamsters.

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12 December 2020

Human prion protein cDNA: molecular cloning, chromosomal mapping, and biological implications

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12 December 2020

Immunoseparation of Prion protein-enriched domains from other detergent-resistant membrane fractions, isolated from neuronal cells

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12 December 2020

Monoclonal antibodies inhibit prion replication and delay the development of prion disease

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12 December 2020

Overexpression of PrPC and its antiapoptosis function in gastric cancer

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12 December 2020

Degenerative disease of the central nervous system in New Guinea; the endemic occurrence of kuru in the native population

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12 December 2020

Synthetic mammalian prions

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12 December 2020

Prolongation of scrapie incubation period by an injection of dextran sulphate 500 within the month before or after infection.

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12 December 2020

A prion protein cycles between the cell surface and an endocytic compartment in cultured neuroblastoma cells

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12 December 2020

Studies of the structure of the metastasis-associated 67 kDa laminin binding protein: fatty acid acylation and evidence supporting dimerization of the 32 kDa gene product to form the mature protein

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12 December 2020

A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits.

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12 December 2020

Beta-sheet breaker peptides reverse conformation of pathogenic prion proteins

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12 December 2020

PrPC directly interacts with proteins involved in signaling pathways

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12 December 2020

Nucleotide sequence for a major messenger RNA for a 40 kilodalton polypeptide that is under translational control in mouse tumor cells

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12 December 2020

Spongiform encephalopathy in a nyala (Tragelaphus angasi)

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12 December 2020

Evaluation of anti-prion activity of congo red and its derivatives in experimentally infected hamsters

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12 December 2020

Porphyrin and phthalocyanine antiscrapie compounds.

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12 December 2020

PrPSc incorporation to cells requires endogenous glycosaminoglycan expression

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12 December 2020

Pathologic conformations of prion proteins

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12 December 2020

Specific inhibition of pathological prion protein accumulation by small interfering RNAs

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12 December 2020

Cell-surface prion protein interacts with glycosaminoglycans

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12 December 2020

The abnormal isoform of the prion protein accumulates in late-endosome-like organelles in scrapie-infected mouse brain

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12 December 2020

Bovine prion protein as a modulator of protein kinase CK2

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12 December 2020

Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release

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12 December 2020

Neurotrophin p75 receptor is involved in neuronal damage by prion peptide-(106-126).

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12 December 2020

Potent inhibition of scrapie-associated PrP accumulation by congo red

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12 December 2020

Prion protein protects human neurons against Bax-mediated apoptosis

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12 December 2020

High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells

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12 December 2020

The 37 kDa/67 kDa laminin receptor is required for PrP(Sc) propagation in scrapie-infected neuronal cells

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12 December 2020

Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection

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12 December 2020

Slow infections of the central nervous system. II.

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12 December 2020

Branched polyamines cure prion-infected neuroblastoma cells

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12 December 2020

Prion protein is necessary for normal synaptic function

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12 December 2020

Phenothiazines and prion diseases: a potential mechanism of action towards oxidative stress

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12 December 2020

Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP.

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12 December 2020

Analysis of nuclear localization of laminin binding protein precursor p40 (LBP/p40)

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12 December 2020

Imbalance of antioxidant defense in mice lacking cellular prion protein.

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12 December 2020

Combined quinacrine and chlorpromazine therapy in fatal familial insomnia

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12 December 2020

Prion protein gene variation among primates

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12 December 2020

NMR structure of the mouse prion protein domain PrP(121-231)

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12 December 2020

Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP.

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12 December 2020

A new variant of Creutzfeldt-Jakob disease in the UK.

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12 December 2020

Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells

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12 December 2020

Interaction of PrP with NRAGE, a protein involved in neuronal apoptosis

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12 December 2020

The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9

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12 December 2020

Adeno-associated viral vector-mediated ApoE expression in Alzheimer's disease mice: low CNS immune response, long-term expression, and astrocyte specificity

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12 December 2020

RNA aptamers specifically interact with the prion protein PrP.

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12 December 2020

The cellular prion protein binds copper in vivo

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12 December 2020

Identification of candidate proteins binding to prion protein

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12 December 2020

Functional domains of the 67-kDa laminin receptor precursor.

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12 December 2020

Prions in skeletal muscle

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12 December 2020

Effect of glycosylphosphatidylinositol anchor-dependent and -independent prion protein association with model raft membranes on conversion to the protease-resistant isoform

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12 December 2020

Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein

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12 December 2020

Attempts to restore scrapie prion infectivity after exposure to protein denaturants

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12 December 2020

Cell localization and redistribution of the 67 kD laminin receptor and alpha 6 beta 1 integrin subunits in response to laminin stimulation: an immunogold electron microscopy study

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12 December 2020

Clearance and prevention of prion infection in cell culture by anti-PrP antibodies.

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12 December 2020

Identification of a protein that purifies with the scrapie prion.

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12 December 2020

Effects of beta-sheet breaker peptide polymers on scrapie-infected mouse neuroblastoma cells and their affinities to prion protein fragment PrP(81-145).

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12 December 2020

Fatal familial insomnia and dysautonomia with selective degeneration of thalamic nuclei

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12 December 2020

Localization of a human gene homologous to the PrP gene on the p arm of chromosome 20 and detection of PrP-related antigens in normal human brain

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12 December 2020

A candidate marsupial PrP gene reveals two domains conserved in mammalian PrP proteins

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12 December 2020

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

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12 December 2020

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

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12 December 2020

Modulation of serotonergic receptor signaling and cross-talk by prion protein.

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12 December 2020

Tumor necrosis factor attenuates prion protein-deficient neuronal cell death by increases in anti-apoptotic Bcl-2 family proteins.

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12 December 2020

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

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12 December 2020

The cellular prion protein PrPc is expressed in human enterocytes in cell-cell junctional domains

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12 December 2020

The mRNA encoding the scrapie agent protein is present in a variety of non-neuronal cells

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12 December 2020

Cellular isoform of the scrapie agent protein participates in lymphocyte activation

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12 December 2020

The expanded octarepeat domain selectively binds prions and disrupts homomeric prion protein interactions

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12 December 2020

Cellular prion protein/laminin receptor: distribution in adult central nervous system and characterization of an isoform associated with a subtype of cortical neurons

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12 December 2020

Breast cancer immunotherapy

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12 December 2020

A novel recombinant adeno-associated virus vaccine reduces behavioral impairment and beta-amyloid plaques in a mouse model of Alzheimer's disease

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12 December 2020

Isolation of a tumor cell laminin receptor

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12 December 2020

Mucosal vaccination delays or prevents prion infection via an oral route.

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12 December 2020

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

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12 December 2020

Complementary hydropathy identifies a cellular prion protein receptor

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12 December 2020

A trans-dominant negative 37kDa/67kDa laminin receptor mutant impairs PrP(Sc) propagation in scrapie-infected neuronal cells.

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12 December 2020

Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor

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12 December 2020

Prophylactic potential of pentosan polysulphate in transmissible spongiform encephalopathies

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12 December 2020

Effectiveness of anthracycline against experimental prion disease in Syrian hamsters.

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12 December 2020

Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein

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12 December 2020

A novel generation of heparan sulfate mimetics for the treatment of prion diseases.

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12 December 2020

Direct interaction between prion protein and tubulin

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12 December 2020

Protein processing in lysosomes: the new therapeutic target in neurodegenerative disease

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12 December 2020

Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines

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12 December 2020

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.

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12 December 2020

Early destruction of the extracellular matrix around parvalbumin-immunoreactive interneurons in Creutzfeldt-Jakob disease.

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12 December 2020

Assignment of the human and mouse prion protein genes to homologous chromosomes

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12 December 2020

Normal prion protein has an activity like that of superoxide dismutase.

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12 December 2020

The 37-kDa/67-kDa laminin receptor acts as a receptor for infectious prions and is inhibited by polysulfated glycanes

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12 December 2020

Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

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12 December 2020

The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP).

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12 December 2020

Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies

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12 December 2020

A putative receptor for Venezuelan equine encephalitis virus from mosquito cells

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12 December 2020

Localization of the mRNA for a chicken prion protein by in situ hybridization

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12 December 2020

A human, compact, fully functional anti-ErbB2 antibody as a novel antitumour agent.

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12 December 2020

Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state

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12 December 2020

Function of PrP(C) as a copper-binding protein at the synapse

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12 December 2020

Prion-protein-specific aptamer reduces PrPSc formation

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12 December 2020

In vitro generation of infectious scrapie prions.

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12 December 2020

PrP knock-out and PrP transgenic mice in prion research

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12 December 2020

The cellular prion protein (PrP) selectively binds to Bcl-2 in the yeast two-hybrid system

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12 December 2020

The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells

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12 December 2020

AAV2-mediated gene delivery to monkey putamen: evaluation of an infusion device and delivery parameters

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12 December 2020

A 33-kDa polypeptide with homology to the laminin receptor: component of translation machinery

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12 December 2020

Heparin-like molecules bind differentially to prion-proteins and change their intracellular metabolic fate

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12 December 2020

The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein

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12 December 2020

Novel proteinaceous infectious particles cause scrapie

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12 December 2020

Cellular prion protein binds laminin and mediates neuritogenesis

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12 December 2020

Primary cultured neurons devoid of cellular prion display lower responsiveness to staurosporine through the control of p53 at both transcriptional and post-transcriptional levels

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12 December 2020

Normal isoform of amyloid protein (PrP) in brains of spawning salmon.

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12 December 2020

Different isoforms of the non-integrin laminin receptor are present in mouse brain and bind PrP.

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12 December 2020

Spongiform encephalopathy in a cat

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12 December 2020

Seventeen copies of the human 37 kDa laminin receptor precursor/p40 ribosome-associated protein gene are processed pseudogenes arisen from retropositional events.

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12 December 2020

Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo

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12 December 2020

Molecular biology of prion diseases

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12 December 2020

Letter: Possible person-to-person transmission of Creutzfeldt-Jakob disease

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12 December 2020

Bovine Doppel (Dpl) and prion protein (PrP) expression on lymphoid tissue and circulating leukocytes

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12 December 2020

LBP-p40 binds DNA tightly through associations with histones H2A, H2B, and H4.

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12 December 2020

Congo red prolongs the incubation period in scrapie-infected hamsters.

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12 December 2020

Does the agent of scrapie replicate without nucleic acid?

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12 December 2020

Prion protein-specific antibodies for therapeutic intervention of transmissible spongiform encephalopathies

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12 December 2020

Scrapie prion proteins are synthesized in neurons

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12 December 2020

Late treatment with polyene antibiotics can prolong the survival time of scrapie-infected animals

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12 December 2020

Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets

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12 December 2020

Prion protein PrPc interacts with molecular chaperones of the Hsp60 family

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12 December 2020

Cationic Lipopolyamines Induce Degradation of PrPSc in Scrapie-Infected Mouse Neuroblastoma Cells

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12 December 2020

Signal transduction through prion protein

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12 December 2020

Development of a safe oral Abeta vaccine using recombinant adeno-associated virus vector for Alzheimer's disease.

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12 December 2020

Prion protein conformation in a patient with sporadic fatal insomnia

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12 December 2020

Cellular prion protein sensitizes neurons to apoptotic stimuli through Mdm2-regulated and p53-dependent caspase 3-like activation

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12 December 2020

Scrapie prion protein contains a phosphatidylinositol glycolipid

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12 December 2020

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

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12 December 2020

Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

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12 December 2020

Prion protein prevents human breast carcinoma cell line from tumor necrosis factor alpha-induced cell death

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12 December 2020

Heparan sulfate is a cellular receptor for purified infectious prions.

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12 December 2020

Molecular genetics of human prion diseases

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12 December 2020

Self-replication and scrapie

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12 December 2020

Cellular prion protein function in copper homeostasis and redox signalling at the synapse

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12 December 2020

The cellular prion protein binds copper in vivo

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12 December 2020

10.1007/S10571-006-9121-1

Identifiers

DOI

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15 August 2017

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