Changing the p53 master regulatory network: ELEMENTary, my dear Mr Watson (Q36777343)

16 August 2017

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title

Changing the p53 master regulatory network: ELEMENTary, my dear Mr Watson (English)

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16 August 2017

D Menendez

1

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16 August 2017

A Inga

series ordinal

2

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16 August 2017

J J Jordan

series ordinal

3

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16 August 2017

M A Resnick

series ordinal

4

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16 August 2017

language of work or name

English

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publication date

1 April 2007

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16 August 2017

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16 August 2017

volume

26

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16 August 2017

issue

15

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16 August 2017

page(s)

2191-2201

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Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction.

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

p53--a key player in tumoral and evolutionary adaptation: a lesson from the Israeli blind subterranean mole rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

MDM2 SNP309 Accelerates Tumor Formation in a Gender-Specific and Hormone-Dependent Manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

MDM2 SNP309 accelerates colorectal tumour formation in women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Dominant-negative p53 mutations selected in yeast hit cancer hot spots

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

A polymorphic microsatellite that mediates induction of PIG3 by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Regulation of p53 downstream genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Definition of a consensus binding site for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

A simple p53 functional assay for screening cell lines, blood, and tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

A transcriptionally active DNA-binding site for human p53 protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Transcriptional repression mediated by the p53 tumour suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

The p53MH algorithm and its application in detecting p53-responsive genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Allosteric activation of latent p53 tetramers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Functional dissection of sequence-specific NKX2-5 DNA binding domain mutations associated with human heart septation defects using a yeast-based system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Novel human p53 mutations that are toxic to yeast can enhance transactivation of specific promoters and reactivate tumor p53 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Transcriptional repression by p53 through direct binding to a novel DNA element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Structural basis of DNA recognition by p53 tetramers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Allosteric effects of DNA on transcriptional regulators

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

The P53 pathway: what questions remain to be explored?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Stat3 contributes to keloid pathogenesis via promoting collagen production, cell proliferation and migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Practical strategies for discovering regulatory DNA sequence motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Twenty years of p53 research: structural and functional aspects of the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

p53 linear diffusion along DNA requires its C terminus

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

How p53 binds DNA as a tetramer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

A genomic map of p53 binding sites identifies novel p53 targets involved in an apoptotic network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

DNA bending is essential for the site-specific recognition of DNA response elements by the DNA binding domain of the tumor suppressor protein p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

p53-induced DNA bending and twisting: p53 tetramer binds on the outer side of a DNA loop and increases DNA twisting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Comparison of the effect of mutant and wild-type p53 on global gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

The IARC TP53 database: new online mutation analysis and recommendations to users

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Isolation of Temperature-sensitive p53 Mutations from a Comprehensive Missense Mutation Library

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Role of a p53 polymorphism in the development of human papillomavirus-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Chromosomal site-specific double-strand breaks are efficiently targeted for repair by oligonucleotides in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

In vivo site-directed mutagenesis using oligonucleotides

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Kinetics of p53 binding to promoter sites in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Two polymorphic variants of wild-type p53 differ biochemically and biologically

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Discrimination of DNA Binding Sites by Mutant p53 Proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

p53 tagged sites from human genomic DNA.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

21 January 2018

Surfing the p53 network

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Interaction of p53 with its consensus DNA-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

A global map of p53 transcription-factor binding sites in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Comparative binding of p53 to its promoter and DNA recognition elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

P53-responsive genes and the potential for cancer diagnostics and therapeutics development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Identification and classification of p53-regulated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

Repression of RNA polymerase I transcription by the tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

The C-terminus of p53: the more you learn the less you know

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

7 January 2021

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

7 January 2021

p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

7 January 2021

Mutation of conserved domain II alters the sequence specificity of DNA binding by the p53 protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

7 January 2021

The UMD TP53 database and website: update and revisions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

7 January 2021

Screening patients for heterozygous p53 mutations using a functional assay in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

7 January 2021

Transcriptional regulation in the yeast GAL gene family: a complex genetic network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

7 January 2021

Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

7 January 2021

The delitto perfetto approach to in vivo site-directed mutagenesis and chromosome rearrangements with synthetic oligonucleotides in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

7 January 2021

A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210277

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210277

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Dimensions Publication ID

16 August 2017

1010350658

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1 reference