Coordinating TLR-activated signaling pathways in cells of the immune system (Q36885368)

16 August 2017

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title

Coordinating TLR-activated signaling pathways in cells of the immune system (English)

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16 August 2017

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Ashish Banerjee

1

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PubMed ID

17637696

16 August 2017

Steve Gerondakis

series ordinal

2

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16 August 2017

17 July 2007

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Immunology & Cell Biology

16 August 2017

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16 August 2017

85

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16 August 2017

6

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16 August 2017

420-424

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TIRAP: an adapter molecule in the Toll signaling pathway

16 August 2017

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide-stimulated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Ubiquitin, TAK1 and IKK: is there a connection?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Phosphorylation of NF-kappaB1/p105 by oncoprotein kinase Tpl2: implications for a novel mechanism of Tpl2 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Proteolytic processing of NF-kappa B/I kappa B in human monocytes. ATP-dependent induction by pro-inflammatory mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Direct phosphorylation of NF-kappaB1 p105 by the IkappaB kinase complex on serine 927 is essential for signal-induced p105 proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

IkappaB kinase is an essential component of the Tpl2 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Identification of a macrophage-specific chromatin signature in the IL-10 locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Variegation of the immune response with dendritic cells and pathogen recognition receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

ERK1-/- mice exhibit Th1 cell polarization and increased susceptibility to experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Translating innate immunity into immunological memory: implications for vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Toll-like receptor ligands directly promote activated CD4+ T cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

Control of B-cell responses by Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

7 January 2021

Toll-like receptor signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

7 January 2021

p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

7 January 2021

How C-type lectins detect pathogens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

7 January 2021

Toll-like receptors: linking innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

7 January 2021

CpG-oligodeoxynucleotides co-stimulate primary T cells in the absence of antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100098

7 January 2021

Identifiers

DOI

10.1038/SJ.ICB.7100098

1 reference

16 August 2017

1 reference

PubMed ID

17637696