Ageing and the pathogenesis of osteoarthritis. (Q37078239)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27192932%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

review article

1 reference

title

Ageing and the pathogenesis of osteoarthritis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27192932%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

0 references

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27192932%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1

Richard F Loeser

1 reference

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2 April 2020

author name string

John A Collins

series ordinal

2

1 reference

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2 April 2020

language of work or name

English

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publication date

19 May 2016

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Nature Reviews Rheumatology

2 April 2020

published in

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2 April 2020

volume

12

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2 April 2020

page(s)

412-420

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2 April 2020

issue

7

1 reference

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2016.65

2 April 2020

exact match

0 references

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29 September 2017

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Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice

29 September 2017

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Growth stimulation leads to cellular senescence when the cell cycle is blocked

29 September 2017

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Mitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalance

29 September 2017

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Sirtuins in mammals: insights into their biological function

29 September 2017

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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

29 September 2017

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Cytokine production in the infrapatellar fat pad: another source of cytokines in knee synovial fluids.

29 September 2017

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Basic FGF mediates an immediate response of articular cartilage to mechanical injury

29 September 2017

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Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritis human articular knee cartilage: a study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee

29 September 2017

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Inflamm-aging. An evolutionary perspective on immunosenescence

29 September 2017

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Interleukin-6: a cytokine for gerontologists

29 September 2017

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Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor γ coactivator 1α

29 September 2017

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Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

27 June 2018

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27 June 2018

Aging and osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Stimulation of BMP-2 expression by pro-inflammatory cytokines IL-1 and TNF-alpha in normal and osteoarthritic chondrocytes

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Economics of osteoarthritis: a global perspective

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Establishment of a rabbit model to study the influence of advanced glycation end products accumulation on osteoarthritis and the protective effect of pioglitazone.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Ageing is associated with reduction of mechanically-induced activation of Smad2/3P signaling in articular cartilage.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Editorial: inflammatory activity in symptomatic knee osteoarthritis: not all inflammation is local

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Inflamm-aging does not simply reflect increases in pro-inflammatory markers.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Transient activation of p53 in G2 phase is sufficient to induce senescence.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Necessary and sufficient role for a mitosis skip in senescence induction.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Is osteoarthritis a metabolic disease?

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Sarcopenic obesity is more closely associated with knee osteoarthritis than is nonsarcopenic obesity: a cross-sectional study

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Elevation of cartilage AGEs does not accelerate initiation of canine experimental osteoarthritis upon mild surgical damage.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938009

Male IL-6 gene knock out mice developed more advanced osteoarthritis upon aging

4 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.65

Infrapatellar fat pad of patients with end-stage osteoarthritis inhibits catabolic mediators in cartilage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.65

DNA damage, discoordinated gene expression and cellular senescence in osteoarthritic chondrocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.65

The relationship between ultra-short telomeres, aging of articular cartilage and the development of human hip osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.65

Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.65

Low-level increases in serum C-reactive protein are present in early osteoarthritis of the knee and predict progressive disease

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27192932

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRRHEUM.2016.65

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27192932%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27192932%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference