Regulated proteolysis of APP and ApoE receptors (Q37139428)

18 August 2017

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title

Regulated proteolysis of APP and ApoE receptors (English)

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18 August 2017

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Hyang-Sook Hoe

1

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PubMed ID

18415033

18 August 2017

G William Rebeck

series ordinal

2

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18 August 2017

1 February 2008

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18 August 2017

Molecular Neurobiology

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18 August 2017

37

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18 August 2017

64-72

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18 August 2017

1

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https://scigraph.springernature.com/pub.10.1007/s12035-008-8017-0

18 August 2017

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cites work

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12035-008-8017-0

The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12035-008-8017-0

Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12035-008-8017-0

Low density lipoprotein receptor-related proteins (LRPs), Alzheimer's and cognition

21 January 2018

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12 December 2020

Proteolysis and membrane capture of F-spondin generates combinatorial guidance cues from a single molecule

1 reference

12 December 2020

Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta

1 reference

12 December 2020

F-spondin: a gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension

1 reference

12 December 2020

The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease

1 reference

12 December 2020

A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference

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12 December 2020

Apolipoprotein E receptor 2 interactions with the N-methyl-D-aspartate receptor

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12 December 2020

F-spondin and mindin: two structurally and functionally related genes expressed in the hippocampus that promote outgrowth of embryonic hippocampal neurons

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12 December 2020

A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin

1 reference

12 December 2020

Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation.

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12 December 2020

Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11alpha.

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12 December 2020

Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice.

1 reference

12 December 2020

cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein

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12 December 2020

Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein

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12 December 2020

Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development

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12 December 2020

Modulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains.

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12 December 2020

Gene identification in Alzheimer's disease

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12 December 2020

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

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12 December 2020

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

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12 December 2020

Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning

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12 December 2020

Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members

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12 December 2020

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12 December 2020

Accumulation of F-spondin in injured peripheral nerve promotes the outgrowth of sensory axons

1 reference

12 December 2020

Generation of the β-Amyloid Peptide and the Amyloid Precursor Protein C-terminal Fragment γ Are Potentiated by FE65L1

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12 December 2020

Neurite outgrowth and the amyloid protein precursor.

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12 December 2020

The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate.

1 reference

12 December 2020

Apolipoprotein E receptors: linking brain development and Alzheimer's disease

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12 December 2020

Low density lipoprotein receptor-related protein (LRP) interacts with presenilin 1 and is a competitive substrate of the amyloid precursor protein (APP) for gamma-secretase

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12 December 2020

Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2

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12 December 2020

Binding of purified Reelin to ApoER2 and VLDLR mediates tyrosine phosphorylation of Disabled-1

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12 December 2020

The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3

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12 December 2020

The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

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12 December 2020

Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination

1 reference

12 December 2020

Catalytic activity of human ADAM33

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12 December 2020

Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein

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12 December 2020

F-spondin promotes nerve precursor differentiation

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12 December 2020

Amyloid precursor protein cytoplasmic domain antagonizes reelin neurite outgrowth inhibition of hippocampal neurons.

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12 December 2020

Expression of human FE65 in amyloid precursor protein transgenic mice is associated with a reduction in beta-amyloid load.

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12 December 2020

Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein

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12 December 2020

Regulation of matrix metalloproteinase activity

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12 December 2020

Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases

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12 December 2020

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

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12 December 2020

ApoE isoforms affect neuronal N-methyl-D-aspartate calcium responses and toxicity via receptor-mediated processes

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12 December 2020

Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase

1 reference

12 December 2020

The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled

1 reference

12 December 2020

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

1 reference

12 December 2020

Low-density lipoprotein receptor-related protein levels and endocytic function are reduced by overexpression of the FE65 adaptor protein, FE65L1.

1 reference

12 December 2020

Association of membrane-bound amyloid precursor protein APP with the apolipoprotein E receptor LRP.

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12 December 2020

Regulation of ApoE receptor proteolysis by ligand binding

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12 December 2020

The generation and function of soluble apoE receptors in the CNS

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12 December 2020

Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner

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12 December 2020

ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin

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12 December 2020

The metalloprotease inhibitor TIMP-3 regulates amyloid precursor protein and apolipoprotein E receptor proteolysis.

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12 December 2020

Apolipoprotein receptor 2 and X11 alpha/beta mediate apolipoprotein E-induced endocytosis of amyloid-beta precursor protein and beta-secretase, leading to amyloid-beta production

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12 December 2020

Alzheimer's disease: genes, proteins, and therapy

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12 December 2020

The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein

1 reference

12 December 2020

Selective localization of amyloid precursor-like protein 1 in the cerebral cortex postsynaptic density

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12 December 2020

Postnatal shifts of interneuron position in the neocortex of normal and reeler mice: evidence for inward radial migration

1 reference

12 December 2020

Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease.

1 reference

12 December 2020

Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein

1 reference

12 December 2020

Lipoprotein receptors in the nervous system

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12 December 2020

FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein.

1 reference

12 December 2020

Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation

1 reference

12 December 2020

Apolipoprotein E is a relevant susceptibility gene that affects the rate of expression of Alzheimer's disease

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12 December 2020

Reelin is a ligand for lipoprotein receptors

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12 December 2020

Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid

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12 December 2020

Mindin/F-spondin family: novel ECM proteins expressed in the zebrafish embryonic axis

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12 December 2020

The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors

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12 December 2020

F-spondin is a contact-repellent molecule for embryonic motor neurons.

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12 December 2020

Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein

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12 December 2020

RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.

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12 December 2020

Disabled1 regulates the intracellular trafficking of reelin receptors

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12 December 2020

Differential reelin-induced enhancement of NMDA and AMPA receptor activity in the adult hippocampus.

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12 December 2020

Mints, Munc18-interacting proteins in synaptic vesicle exocytosis

1 reference

12 December 2020

The effects of ABCA1 on cholesterol efflux and Abeta levels in vitro and in vivo.

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12 December 2020

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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12 December 2020

F-spondin interaction with the apolipoprotein E receptor ApoEr2 affects processing of amyloid precursor protein

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12 December 2020

hFE65L influences amyloid precursor protein maturation and secretion

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12 December 2020

Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticity

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12 December 2020

Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?

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12 December 2020

Demonstration by fluorescence resonance energy transfer of two sites of interaction between the low-density lipoprotein receptor-related protein and the amyloid precursor protein: role of the intracellular adapter protein Fe65.

1 reference

12 December 2020

The amino-terminal region of amyloid precursor protein is responsible for neurite outgrowth in rat neocortical explant culture.

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12 December 2020

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction

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12 December 2020

FE65 Interaction with the ApoE Receptor ApoEr2

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12 December 2020

NMDA receptor surface trafficking and synaptic subunit composition are developmentally regulated by the extracellular matrix protein Reelin.

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12 December 2020

Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway

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12 December 2020

Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg.

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12 December 2020

Mice deficient for the amyloid precursor protein gene.

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12 December 2020

DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing

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12 December 2020

ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3

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12 December 2020

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

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12 December 2020

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12 December 2020

Genome structure and chromosomal mapping of the gene for Fe65L2 interacting with Alzheimer's beta-amyloid precursor protein

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12 December 2020

Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1

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12 December 2020

Inhibition of ADAMTS4 (aggrecanase-1) by tissue inhibitors of metalloproteinases (TIMP-1, 2, 3 and 4)

1 reference

12 December 2020

F-Spondin is required for accurate pathfinding of commissural axons at the floor plate

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12 December 2020

Receptor clustering is involved in Reelin signaling

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12 December 2020

Breaking up the tie: disintegrin-like metalloproteinases as regulators of cell migration in inflammation and invasion.

1 reference

12 December 2020

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2

1 reference

12 December 2020

Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases

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12 December 2020

Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage

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12 December 2020

10.1007/S12035-008-8017-0

Identifiers

DOI

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18 August 2017

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PubMed ID

18415033