Promotion of cellular NAD(+) anabolism: therapeutic potential for oxidative stress in ageing and Alzheimer's disease. (Q37181486)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18522897%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

review article

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title

Promotion of cellular NAD(+) anabolism: therapeutic potential for oxidative stress in ageing and Alzheimer's disease (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18522897%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18522897%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Gilles J. Guillemin

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18522897%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Ross Grant

series ordinal

3

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8 January 2020

publication date

1 May 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18522897%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

published in

Neurotoxicity Research

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8 January 2020

volume

13

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8 January 2020

issue

3-4

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8 January 2020

page(s)

173-184

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18522897%20AND%20SRC:MED&resulttype=core&format=json

H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion

8 January 2020

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Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels

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SIRT1 transgenic mice show phenotypes resembling calorie restriction

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The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension

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Increased poly(ADP-ribosyl)ation of nuclear proteins in Alzheimer's disease

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Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported.

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

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Oxidative stress as a mechanism for quinolinic acid-induced hippocampal damage: protection by melatonin and deprenyl

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Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology

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Poly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functions

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Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

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P53- and CD95-associated apoptosis in neurodegenerative diseases

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Effects of N omega-nitro-L-arginine and L-arginine on quinolinic acid-induced lipid peroxidation

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Biomarkers of oxidative/nitrosative stress: an approach to disease prevention

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beta-Amyloid-associated free radical oxidative stress and neurotoxicity: implications for Alzheimer's disease

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NAD+ metabolism in health and disease

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RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

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12 December 2020

The role of poly(ADP-ribose) in the DNA damage signaling network

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12 December 2020

Oxidative imbalance in Alzheimer's disease

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Carboxyl-terminal fragment of Alzheimer's APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity

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The molecular bases of Alzheimer's disease and other neurodegenerative disorders

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Indoleamine 2,3 dioxygenase and quinolinic acid immunoreactivity in Alzheimer's disease hippocampus

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Neuroscience. NAD to the rescue

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Amyloid beta-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells.

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12 December 2020

Involvement of NAD-poly(ADP-ribose) metabolism in p53 regulation and its consequences

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A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

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12 December 2020

Identifiers

DOI

10.1007/BF03033501

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18522897%20AND%20SRC:MED&resulttype=core&format=json

release_u6qx2ug47vef7nk4riqx6qrvwu

8 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/u6qx2ug47vef7nk4riqx6qrvwu

24 November 2022

mapped directly with Wikidata item

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