Mitoenergetic failure in Alzheimer disease (Q36522646)

14 August 2017

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title

Mitoenergetic failure in Alzheimer disease (English)

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14 August 2017

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Mordhwaj S Parihar

1

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PubMed ID

16807300

14 August 2017

Gregory J Brewer

series ordinal

2

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14 August 2017

28 June 2006

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American Journal of Physiology - Cell Physiology

14 August 2017

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14 August 2017

292

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14 August 2017

C8-23

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14 August 2017

1

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The expression of creatine kinase isoenzymes in neocortex of patients with neurodegenerative disorders: Alzheimer's and Pick's disease.

14 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Gradual alteration of mitochondrial structure and function by beta-amyloids: importance of membrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Delaying the mitochondrial decay of aging with acetylcarnitine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Oxidative stress in neurodegeneration: cause or consequence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial uncoupling proteins in the CNS: in support of function and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The fluorodeoxyglucose 18F scan in Alzheimer's disease and multi-infarct dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The new life of a centenarian: signalling functions of NAD(P).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Protein oxidation in aging, disease, and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Selective distribution of lactate dehydrogenase isoenzymes in neurons and astrocytes of human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Brain metabolism and brain disease: is metabolic deficiency the proximate cause of Alzheimer dementia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial involvement in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Proteomic identification of proteins oxidized by Abeta(1-42) in synaptosomes: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Abnormally phosphorylated tau protein related to the formation of neurofibrillary tangles and neuropil threads in the cerebral cortex of sheep and goat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Neuronal plasticity and stressor toxicity during aging

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Prevention of age-related dysregulation of calcium dynamics by estrogen in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial H(+) leak and ROS generation: an odd couple

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

On the mechanisms of neuroprotection by creatine and phosphocreatine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Diversity in the Sir2 family of protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Structural and functional changes in proteins induced by free radical-mediated oxidative stress and protective action of the antioxidants N-tert-butyl-alpha-phenylnitrone and vitamin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Thiamine-dependent enzyme changes in temporal cortex of patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Systematic identification of human mitochondrial disease genes through integrative genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

beta-Amyloid fragment 25-35 selectively decreases complex IV activity in isolated mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Structure and assembly of cytochrome c oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Coupling between catalytic sites and the proton channel in F1F0-type ATPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The AMP-activated protein kinase cascade--a unifying system for energy control

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Beta-amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Oxidative stress, mitochondrial function, and acute glutamate excitotoxicity in cultured cerebellar granule cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Extracellular metabolites in the cortex and hippocampus of epileptic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Impairment in mitochondrial cytochrome oxidase gene expression in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Evidence for physiological down-regulation of brain oxidative phosphorylation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Decreased expression of nuclear and mitochondrial DNA-encoded genes of oxidative phosphorylation in association neocortex in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Glutamate neurotoxicity and diseases of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

MtDNA mutations in aging and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

A focus on the synapse for neuroprotection in Alzheimer disease and other dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Structural correlates of cognition in dementia: quantification and assessment of synapse change.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Impaired glutamate clearance as a consequence of energy failure caused by MPP(+) in astrocytic cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Induction of the mitochondrial permeability transition by the DNA alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine. Sorting cause and consequence of mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondria in health and disease: perspectives on a new mitochondrial biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Detection of Free Radicals by Microdialysis/Spin Trapping Epr Following Focal Cerebral Ischemia-Reperfusion and a Cautionary Note on the Stability of 5,5-Dimethyl-1-Pyrroline N-Oxide (DMPO)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Failing energetics in failing hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Phosphotransfer networks and cellular energetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Biochemistry of mitochondrial nitric-oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Regional cerebral oxygen supply and utilization in dementia. A clinical and physiological study with oxygen-15 and positron tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

How do uncoupling proteins uncouple?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Abnormalities of mitochondrial enzymes in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Oxidative stress and a key metabolic enzyme in Alzheimer brains, cultured cells, and an animal model of chronic oxidative deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Oxygen free radicals and cardiac reperfusion abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient glia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Reactive oxygen species and the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Management of cellular energy by the AMP-activated protein kinase system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Amyloid, the presenilins and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Neuronal-astrocytic and cytosolic-mitochondrial metabolite trafficking during brain activation, hyperammonemia and energy deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The metabolic implications of intracellular circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Oxidative stress and redox-active iron in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Modification of endoplasmic reticulum Ca2+ stores by select oxidants produces changes reminiscent of those in cells from patients with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

31P NMR detection of subcellular creatine kinase fluxes in the perfused rat heart: contractility modifies energy transfer pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

NMDA-dependent superoxide production and neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Synaptic pathology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Navigating novel mechanisms of cellular plasticity with the NAD+ precursor and nutrient nicotinamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Changes in Na+,K(+)-ATPase, Ca2(+)-ATPase and some soluble enzymes related to energy metabolism in brains of patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Calorie restriction extends yeast life span by lowering the level of NADH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Excitatory amino acids as a final common pathway for neurologic disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial superoxide decreases yeast survival in stationary phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Increased poly(ADP-ribosyl)ation of nuclear proteins in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Negative control of p53 by Sir2alpha promotes cell survival under stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Cellular bases of brain energy metabolism and their relevance to functional brain imaging: evidence for a prominent role of astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Cellular mechanisms of brain energy metabolism and their relevance to functional brain imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Time-course of mitochondrial gene expressions in mice brains: implications for mitochondrial dysfunction, oxidative damage, and cytochrome c in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial dysfunction measured in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Oxidative stress hypothesis in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The central role of the mitochondrial megachannel in apoptosis: evidence obtained with intact cells, isolated mitochondria, and purified protein complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Emerging neuroprotective strategies for Alzheimer's disease: dietary restriction, telomerase activation, and stem cell therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Pathways towards and away from Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

What do mitochondrial diseases teach us about normal mitochondrial functions...that we already knew: threshold expression of mitochondrial defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Glucose-induced activation of pyruvate dehydrogenase in isolated rat pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Does nitric oxide modulate mitochondrial energy generation and apoptosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Increased vulnerability of brain mitochondria in diabetic (Goto-Kakizaki) rats with aging and amyloid-beta exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Membrane-disordering effects of beta-amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Selective targeting of bioactive compounds to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Metabolism of rat brain mitochondria. Studies on the potassium ion-stimulated oxidation of pyruvate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Apoptosis and necrosis: different execution of the same death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Selective increase in lipid peroxidation in the inferior temporal cortex in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Transport of metabolic substrates through the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Poly (ADP-ribose) polymerase, nitric oxide and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Peroxynitrite reactions and formation in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Redox signaling: hydrogen peroxide as intracellular messenger

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Ca2+ release from mitochondria induced by prooxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Composition, structure, and function of complex III of the respiratory chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Regional cerebral blood flow measurements by 133Xe-inhalation: methodology and applications in neuropsychology and psychiatry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondria as all-round players of the calcium game

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Strategic location of calcium channels at transmitter release sites of frog neuromuscular synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Cardiac system bioenergetics: metabolic basis of the Frank-Starling law.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial creatine kinase in human health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Glutathione, oxidative stress and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Redox signaling and the emerging therapeutic potential of thiol antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

An immunochemical study of the pyruvate dehydrogenase deficit in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Molecular determinants of voltage-dependent slow inactivation of the Ca2+ channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Oxidative phosphorylation defects and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Functional alterations in Alzheimer's disease: selective loss of mitochondrial-encoded cytochrome oxidase mRNA in the hippocampal formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Functional alterations in neural circuits in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Evaluating the function of hippocampal subregions with high-resolution MRI in Alzheimer's disease and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Topography of cross-sectional and longitudinal glucose metabolic deficits in Alzheimer's disease. Pathophysiologic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Regulation of NMDA receptor trafficking by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Reduced mitochondrial membrane potential and altered responsiveness of a mitochondrial membrane megachannel in p53-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Purification and characterization of a nitric-oxide synthase from rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Energetics of amino acid transport into brain slices: effects of glucose depletion and substitution of Krebs' cycle intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Cellular stress reactions as putative cholinergic links in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Oxidative damage to mitochondria and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Substrates of energy metabolism of the pituitary and pineal glands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Coupling energy metabolism with a mechanism to support brain-derived neurotrophic factor-mediated synaptic plasticity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The beneficial effects of dietary restriction: reduced oxidative damage and enhanced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial diseases in man and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Some new aspects of creatine kinase (CK): compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Cytochrome oxidase: an endogenous metabolic marker for neuronal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

The interplay between oxidative stress and brain-derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

New clues to Alzheimer's disease: unraveling the roles of amyloid and tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mammalian mitochondrial nitric oxide synthase: characterization of a novel candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Mitochondrial failures in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Crystal structures of adrenodoxin reductase in complex with NADP+ and NADPH suggesting a mechanism for the electron transfer of an enzyme family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

Deficits in cerebral glucose metabolism demonstrated by positron emission tomography in individuals at risk of familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

A molecular approach to the concerted action of kinases involved in energy homoeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00232.2006

10.1152/AJPCELL.00232.2006

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16807300