Cracking the O-GlcNAc code in metabolism. (Q37197417)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647930%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Cracking the O-GlcNAc code in metabolism (English)

1 reference

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29 February 2020

1

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29 February 2020

Min-Dian Li

3

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29 February 2020

author name string

Jay Prakash Singh

2

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29 February 2020

Jing Wu

4

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29 February 2020

Xiaoyong Yang

5

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29 February 2020

publication date

4 May 2013

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Trends in Endocrinology and Metabolism

29 February 2020

published in

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29 February 2020

volume

24

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29 February 2020

issue

6

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29 February 2020

page(s)

301-309

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O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination

29 February 2020

cites work

1 reference

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Glucose sensor O-GlcNAcylation coordinates with phosphorylation to regulate circadian clock

6 September 2017

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Circadian topology of metabolism

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Enhanced cardiac protein glycosylation (O-GlcNAc) of selected mitochondrial proteins in rats artificially selected for low running capacity.

6 September 2017

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Phosphofructokinase 1 glycosylation regulates cell growth and metabolism

6 September 2017

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Non-transcriptional oscillators in circadian timekeeping

6 September 2017

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Loss of the tumor suppressor BAP1 causes myeloid transformation

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Excess protein O-GlcNAcylation and the progression of diabetic cardiomyopathy.

6 September 2017

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Modulation of dynamin-related protein 1 (DRP1) function by increased O-linked-β-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes

6 September 2017

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Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates Akt signaling

6 September 2017

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Social jetlag and obesity

6 September 2017

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Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption

6 September 2017

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Central and peripheral circadian clocks in mammals

6 September 2017

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A role for O-GlcNAcylation in setting circadian clock speed

6 September 2017

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Critical role of O-Linked β-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis

6 September 2017

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GlcNAcylation of histone H2B facilitates its monoubiquitination

6 September 2017

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O-GlcNAcylation, novel post-translational modification linking myocardial metabolism and cardiomyocyte circadian clock.

6 September 2017

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Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

6 September 2017

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Genetics of circadian rhythms in Mammalian model organisms

6 September 2017

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Protein O-linked β-N-acetylglucosamine: a novel effector of cardiomyocyte metabolism and function

6 September 2017

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The circadian clock interacts with metabolic physiology to influence reproductive fitness

6 September 2017

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Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic β-cell function and vascularization.

6 September 2017

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O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver

6 September 2017

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Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease

6 September 2017

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Hallmarks of Cancer: The Next Generation

6 September 2017

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p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

6 September 2017

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O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1

6 September 2017

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Crosstalk between components of circadian and metabolic cycles in mammals

6 September 2017

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Inhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 Adipocytes

6 September 2017

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Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis

6 September 2017

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Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia

6 September 2017

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O-GlcNAc signaling: a metabolic link between diabetes and cancer?

6 September 2017

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Increased expression of beta-N-acetylglucosaminidase in erythrocytes from individuals with pre-diabetes and diabetes

6 September 2017

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A wheel of time: the circadian clock, nuclear receptors, and physiology

6 September 2017

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The mammalian circadian timing system: organization and coordination of central and peripheral clocks

6 September 2017

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Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes

6 September 2017

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O-GlcNAc protein modification in plants: Evolution and function

6 September 2017

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O-GlcNAc modification and the tauopathies: insights from chemical biology

6 September 2017

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Hexosamine flux, the O-GlcNAc modification, and the development of insulin resistance in adipocytes

6 September 2017

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A genome-wide RNAi screen for modifiers of the circadian clock in human cells

6 September 2017

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O-linked N-acetylglucosamine modification of insulin receptor substrate-1 occurs in close proximity to multiple SH2 domain binding motifs

6 September 2017

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Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification

6 September 2017

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Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose

6 September 2017

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O-linked GlcNAc modification of cardiac myofilament proteins: a novel regulator of myocardial contractile function

6 September 2017

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NFkappaB activation is associated with its O-GlcNAcylation state under hyperglycemic conditions

6 September 2017

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Elevation of Global O-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-GlcNAcase Does Not Induce Insulin Resistance

6 September 2017

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Glucose regulation of insulin gene expression in pancreatic beta-cells

6 September 2017

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The meter of metabolism

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Non-canonical glycosyltransferase modulates post-hypoxic cardiac myocyte death and mitochondrial permeability transition

6 September 2017

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Regulation of the O-linked beta-N-acetylglucosamine transferase by insulin signaling.

6 September 2017

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Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity

6 September 2017

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Circadian clocks: 50 years on.

6 September 2017

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Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

6 September 2017

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Dynamic interplay between O-linked N-acetylglucosaminylation and glycogen synthase kinase-3-dependent phosphorylation

6 September 2017

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Glucose mediates the translocation of NeuroD1 by O-linked glycosylation

6 September 2017

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Emerging roles of nuclear protein phosphatases

6 September 2017

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Modeling of a human circadian mutation yields insights into clock regulation by PER2

6 September 2017

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Reduction of O-GlcNAc protein modification does not prevent insulin resistance in 3T3-L1 adipocytes

6 September 2017

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Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats

6 September 2017

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Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability

6 September 2017

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Nuclear receptor expression links the circadian clock to metabolism

6 September 2017

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Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer

6 September 2017

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

6 September 2017

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Protein kinase Czeta mediates insulin-induced glucose transport through actin remodeling in L6 muscle cells

6 September 2017

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The hexosamine signaling pathway: deciphering the "O-GlcNAc code"

6 September 2017

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A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout

6 September 2017

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O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress

6 September 2017

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Protein tyrosine phosphatases in the human genome

6 September 2017

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The transcription factor PDX-1 is post-translationally modified by O-linked N-acetylglucosamine and this modification is correlated with its DNA binding activity and insulin secretion in min6 beta-cells.

6 September 2017

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Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression

6 September 2017

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Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

6 September 2017

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Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

6 September 2017

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O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability

6 September 2017

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Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity

6 September 2017

1 reference

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Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death

6 September 2017

1 reference

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O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats

6 September 2017

1 reference

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Overexpression of glutamine:fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance

6 September 2017

1 reference

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c-Myc Is Glycosylated at Threonine 58, a Known Phosphorylation Site and a Mutational Hot Spot in Lymphomas

6 September 2017

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Coordinated regulation of glutamine:fructose-6-phosphate amidotransferase activity by insulin, glucose, and glutamine. Role of hexosamine biosynthesis in enzyme regulation

6 September 2017

1 reference

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O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation

6 September 2017

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O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy

14 September 2017

1 reference

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Altered O-GlcNAc modification and phosphorylation of mitochondrial proteins in myoblast cells exposed to high glucose.

14 September 2017

1 reference

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Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.

14 September 2017

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Nuclear receptor liver X receptor is O-GlcNAc-modified in response to glucose

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic beta cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

O-GlcNAc modification is an endogenous inhibitor of the proteasome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Insulin activates protein kinases C-zeta and C-lambda by an autophosphorylation-dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Cardioprotection by N-acetylglucosamine linkage to cellular proteins.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Glucosamine-induced insulin resistance is coupled to O-linked glycosylation of Munc18c

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Effects of glucosamine infusion on insulin secretion and insulin action in humans.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

O-GlcNAcylation of BMAL1 regulates circadian rhythms in NIH3T3 fibroblasts

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Exploring leukocyte O-GlcNAcylation as a novel diagnostic tool for the earlier detection of type 2 diabetes mellitus

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Prediction of bladder cancer based on urinary content of MGEA5 and OGT mRNA level.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Hepatic glucose sensing via the CREB coactivator CRTC2.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Posttranslational modifications on protein kinase c isozymes. Effects of epinephrine and phorbol esters

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Prolonged incubation in PUGNAc results in increased protein O-Linked glycosylation and insulin resistance in rat skeletal muscle

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Insulin resistance of glycogen synthase mediated by o-linked N-acetylglucosamine.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Mitochondrial and nucleocytoplasmic isoforms of O-linked GlcNAc transferase encoded by a single mammalian gene

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Human O-GlcNAc transferase (OGT): genomic structure, analysis of splice variants, fine mapping in Xq13.1.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783028

Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase

3 September 2018

1 reference

12 December 2020

Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes. Evidence for O-linked GlcNAc

1 reference

12 December 2020

Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance in multiple insulin sensitive tissues

1 reference

12 December 2020

Elevated O-linked N-acetylglucosamine metabolism in pancreatic beta-cells

1 reference

12 December 2020

Bittersweet memories: linking metabolism to epigenetics through O-GlcNAcylation

1 reference

12 December 2020

10.1016/J.TEM.2013.02.002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647930%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647930%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

23647930

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647930%20AND%20SRC:MED&resulttype=core&format=json