CD8+ T cells in type 1 diabetes (Q37358997)

19 August 2017

1 reference

title

CD8+ T cells in type 1 diabetes (English)

1 reference

19 August 2017

0 references

Sue Tsai

1

1 reference

PubMed ID

19111164

19 August 2017

Afshin Shameli

series ordinal

2

1 reference

PubMed ID

19111164

19 August 2017

Pere Santamaria

series ordinal

3

1 reference

19 August 2017

1 January 2008

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19 August 2017

Advances in Immunology

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19 August 2017

100

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19 August 2017

79-124

1 reference

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique

19 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Autoantibodies to IA-2beta improve diabetes risk assessment in high-risk relatives.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Mechanisms of beta cell death in diabetes: a minor role for CD95.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Transgenic expression of dominant-negative Fas-associated death domain protein in beta cells protects against Fas ligand-induced apoptosis and reduces spontaneous diabetes in nonobese diabetic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

CD154-dependent priming of diabetogenic CD4(+) T cells dissociated from activation of antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

The NOD mouse: a model of immune dysregulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Human CD8 responses to a complete epitope set from preproinsulin: implications for approaches to epitope discovery.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Systemic Administration of Agonist Peptide Blocks the Progression of Spontaneous CD8-Mediated Autoimmune Diabetes in Transgenic Mice Without Bystander Damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Induction of Autoimmune Diabetes by Oral Administration of Autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Immunization of HLA class I transgenic mice identifies autoantigenic epitopes eliciting dominant responses in type 1 diabetes patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Generation and maintenance of autoantigen-specific CD8(+) T cell clones isolated from NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

On the pathogenicity of autoantigen-specific T-cell receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Dominant CTL-inducing epitopes on GAD65 are adjacent to or overlap with dominant Th-inducing epitopes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC gene-controlled near death experience.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Fas is detectable on beta cells in accelerated, but not spontaneous, diabetes in nonobese diabetic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Tissue targeting of T cells by DCs and microenvironments

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Cytotoxic T-Cells From T-Cell Receptor Transgenic NOD8.3 Mice Destroy β-Cells via the Perforin and Fas Pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Different diabetogenic potential of autoaggressive CD8+ clones associated with IFN-gamma-inducible protein 10 (CXC chemokine ligand 10) production but not cytokine expression, cytolytic activity, or homing characteristics.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Antigen-specific induction of regulatory T cells for type 1 diabetes therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Stimulating PD-1???negative signals concurrent with blocking CD154 co-stimulation induces long-term islet allograft survival1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Invariant NKT cells exacerbate type 1 diabetes induced by CD8 T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Mechanisms of PDL1-mediated regulation of autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Beta cell MHC class I is a late requirement for diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Islet beta-cell-specific T cells can use different homing mechanisms to infiltrate and destroy pancreatic islets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

An altered self-peptide with superagonist activity blocks a CD8-mediated mouse model of type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Identification of naturally processed HLA-A2--restricted proinsulin epitopes by reverse immunology.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Cross-presentation, dendritic cells, tolerance and immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

A mouse CD8 T cell-mediated acute autoimmune diabetes independent of the perforin and Fas cytotoxic pathways: possible role of membrane TNF.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

A type 1 diabetes subgroup with a female bias is characterised by failure in tolerance to thyroid peroxidase at an early age and a strong association with the cytotoxic T-lymphocyte-associated antigen-4 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Identification of novel IGRP epitopes targeted in type 1 diabetes patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Beta cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Thymic and postthymic regulation of diabetogenic CD8 T cell development in TCR transgenic nonobese diabetic (NOD) mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Following a diabetogenic T cell from genesis through pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Tissue expression of PD-L1 mediates peripheral T cell tolerance.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

PD-1 regulates self-reactive CD8+ T cell responses to antigen in lymph nodes and tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

PD-1 and its ligands in tolerance and immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Prediction of proteasome cleavage motifs by neural networks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Inhibition of autoimmune diabetes by Fas ligand: the paradox is solved

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

A defect in central tolerance in NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

IA-2 is not required for the development of diabetes in NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Variation in HLA-associated risks of childhood insulin-dependent diabetes in the Finnish population: I. Allele effects at A, B, and DR loci. DiMe Study Group. Childhood Diabetes in Finland

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profiling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Peptide-pulsed immature dendritic cells reduce response to beta cell target antigens and protect NOD recipients from type I diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Toll-like receptors in systemic autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

The frequency and immunodominance of islet-specific CD8+ T-cell responses change after type 1 diabetes diagnosis and treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

In vivo imaging of a diabetogenic CD8+ T cell response during type 1 diabetes progression.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Tracking the recruitment of diabetogenic CD8+ T-cells to the pancreas in real time.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Identification of peptide sequences that potentially trigger HLA-A2.1-restricted cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

The HLA class I A locus affects susceptibility to type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Regulation of type 1 diabetes by NKT cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

A deficiency in the in vivo clearance of apoptotic cells is a feature of the NOD mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Progression of spontaneous autoimmune diabetes is associated with a switch in the killing mechanism used by autoreactive CTL

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

SYFPEITHI: database for MHC ligands and peptide motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Millennium award recipient contribution. Identification of children with early onset and high incidence of anti-islet autoantibodies.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Cross-presentation: underlying mechanisms and role in immune surveillance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Targeted disruption of the protein tyrosine phosphatase-like molecule IA-2 results in alterations in glucose tolerance tests and insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

DRw52-group haplotypes are frequent acceptors of DRw15-Dw2 DQ genes in DQA1-DRB1 recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

IFN-gamma affects homing of diabetogenic T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Contribution of Fas to diabetes development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

A mechanism for the major histocompatibility complex-linked resistance to autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Through Regulation of TCR Expression Levels, an Idd7 Region Gene(s) Interactively Contributes to the Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in Nonobese Diabetic Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

"Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

CD8+ T lymphocytes specific for glutamic acid decarboxylase 90-98 epitope mediate diabetes in NOD SCID mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Endoplasmic reticulum stress caused by overexpression of islet-specific glucose-6-phosphatase catalytic subunit-related protein in pancreatic Beta-cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Cutting edge: elimination of an endogenous adjuvant reduces the activation of CD8 T lymphocytes to transplanted cells and in an autoimmune diabetes model

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Tolerogenic dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Prevention of insulitis and diabetes in beta 2-microglobulin-deficient non-obese diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

HLA genes associated with autoimmunity and progression to disease in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Cytotoxic T cells to an epitope in the islet autoantigen IA-2 are not disease-specific

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

T-cell tolerance by dendritic cells and macrophages as a mechanism for the major histocompatibility complex-linked resistance to autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

'Sensing' autoimmunity in type 1 diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Targeting of pancreatic glia in type 1 diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

An islet-homing NOD CD8+ cytotoxic T cell clone recognizes GAD65 and causes insulitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Autoimmunity versus tolerance: can dying cells tip the balance?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

The enemy within: keeping self-reactive T cells at bay in the periphery

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Monitoring gene expression of TNFR family members by beta-cells during development of autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Type 1 diabetes genes and pathways shared by humans and NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Autoimmune islet destruction in spontaneous type 1 diabetes is not beta-cell exclusive.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Analysis of the roles of CD4+ and CD8+ T cells in autoimmune diabetes of NOD mice using transfer to NOD athymic nude mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Development of autoimmune diabetes in glutamic acid decarboxylase 65 (GAD65) knockout NOD mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

In situ beta cell death promotes priming of diabetogenic CD8 T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900804-3

7 January 2021

10.1016/S0065-2776(08)00804-3

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

19111164