Mitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion (Q37375716)

20 August 2017

Mitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion (English)

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20 August 2017

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Marina Casimir

1

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20 August 2017

Francesco M Lasorsa

2

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20 August 2017

Blanca Rubi

3

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20 August 2017

Dorothée Caille

4

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20 August 2017

Ferdinando Palmieri

5

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20 August 2017

Paolo Meda

6

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20 August 2017

Pierre Maechler

7

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20 August 2017

language of work or name

English

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publication date

7 July 2009

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Journal of Biological Chemistry

20 August 2017

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20 August 2017

284

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20 August 2017

37

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20 August 2017

25004-25014

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Tissue specificity of mitochondrial glutamate pathways and the control of metabolic homeostasis

20 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757205

Diseases caused by defects of mitochondrial carriers: a review

6 September 2017

1 reference

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Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves

6 September 2017

1 reference

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The insulin-like growth factor-I-mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growth

6 September 2017

1 reference

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Mitochondrial GTP regulates glucose-stimulated insulin secretion

6 September 2017

1 reference

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Mitochondrial transporters as novel targets for intracellular calcium signaling.

6 September 2017

1 reference

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In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion

6 September 2017

1 reference

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New mitochondrial carriers: an overview.

6 September 2017

1 reference

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ATP-sensitive potassium channelopathies: focus on insulin secretion

6 September 2017

1 reference

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A fourth ADP/ATP carrier isoform in man: identification, bacterial expression, functional characterization and tissue distribution

6 September 2017

1 reference

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Impaired mitochondrial glutamate transport in autosomal recessive neonatal myoclonic epilepsy

6 September 2017

1 reference

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Beta-cell CaV channel regulation in physiology and pathophysiology

6 September 2017

1 reference

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The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells

6 September 2017

1 reference

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Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution.

6 September 2017

1 reference

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Identification of the human mitochondrial S-adenosylmethionine transporter: bacterial expression, reconstitution, functional characterization and tissue distribution

6 September 2017

1 reference

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The mitochondrial transporter family (SLC25): physiological and pathological implications

6 September 2017

1 reference

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Hierarchy of the beta-cell signals controlling insulin secretion.

6 September 2017

1 reference

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Identification of the mitochondrial glutamate transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms

6 September 2017

1 reference

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Beta-cell mitochondria and insulin secretion: messenger role of nucleotides and metabolites

6 September 2017

1 reference

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Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria

6 September 2017

1 reference

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Triggering and amplifying pathways of regulation of insulin secretion by glucose

6 September 2017

1 reference

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Continuous monitoring of ATP levels in living insulin secreting cells expressing cytosolic firefly luciferase

6 September 2017

1 reference

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Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

6 September 2017

1 reference

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Mitochondrial carrier proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757205

Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors

6 September 2017

1 reference

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Glutamate inhibits protein phosphatases and promotes insulin exocytosis in pancreatic beta-cells.

14 September 2017

1 reference

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Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets.

14 September 2017

1 reference

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Characterization of vesicular glutamate transporter in pancreatic alpha - and beta -cells and its regulation by glucose

14 September 2017

1 reference

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Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues

14 September 2017

1 reference

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Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757205

Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells.

28 September 2017

1 reference

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Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells.

28 September 2017

1 reference

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Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

28 September 2017

1 reference

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Glucose metabolism and glutamate analog acutely alkalinize pH of insulin secretory vesicles of pancreatic beta-cells.

26 June 2018

1 reference

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GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells.

26 June 2018

1 reference

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Activation of acetyl-CoA carboxylase by a glutamate- and magnesium-sensitive protein phosphatase in the islet beta-cell

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757205

Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.

26 June 2018

1 reference

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Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion

2 September 2018

1 reference

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Expression and secretion of alpha1-proteinase inhibitor are regulated by proinflammatory cytokines in human pancreatic islet cells

2 September 2018

1 reference

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Quantitative NAD(P)H/flavoprotein autofluorescence imaging reveals metabolic mechanisms of pancreatic islet pyruvate response

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757205

Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757205

Increase in cellular glutamate levels stimulates exocytosis in pancreatic beta-cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757205

Implication of glutamate in the kinetics of insulin secretion in rat and mouse perfused pancreas

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757205

Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757205

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757205

Induction and degradation of the uncoupling protein thermogenin in brown adipocytes in vitro and in vivo. Evidence for a rapidly degradable pool.

2 September 2018

1 reference

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Acridine orange induces translocation of phosphatidylserine to red blood cell surface

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M109.015495

The stimulus-secretion coupling of amino acid-induced insulin release. Biosynthetic and secretory responses of rat pancreatic islet to L-leucine and L-glutamine

21 January 2018

1 reference

12 December 2020

Regulation of insulin release by factors that also modify glutamate dehydrogenase

1 reference

12 December 2020

Mitochondrial metabolite carrier proteins: purification, reconstitution, and transport studies

1 reference

12 December 2020

Protein kinases, protein phosphorylation, and the regulation of insulin secretion from pancreatic beta-cells

1 reference

12 December 2020

The mitochondrial dicarboxylate carrier is essential for the growth of Saccharomyces cerevisiae on ethanol or acetate as the sole carbon source

1 reference

12 December 2020

Effects of a GTP-insensitive Mutation of Glutamate Dehydrogenase on Insulin Secretion in Transgenic Mice

1 reference

12 December 2020

The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.015495

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

19584051

1 reference