ER stress and unfolded protein response in amyotrophic lateral sclerosis (Q37382212)

20 August 2017

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title

ER stress and unfolded protein response in amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

20 August 2017

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4

Masaaki Matsuoka

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20 August 2017

Kohsuke Kanekura

1

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20 August 2017

Hiroaki Suzuki

series ordinal

2

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20 August 2017

Sadakazu Aiso

series ordinal

3

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20 August 2017

30 January 2009

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20 August 2017

Molecular Neurobiology

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20 August 2017

39

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20 August 2017

2

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20 August 2017

81-89

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https://scigraph.springernature.com/pub.10.1007/s12035-009-8054-3

20 August 2017

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Occurrence of amyotrophic lateral sclerosis among Gulf War veterans

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A clinical trial of creatine in ALS.

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Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

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12 December 2020

Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.

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12 December 2020

D-serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis

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12 December 2020

Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

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12 December 2020

Saccharomyces cerevisiae IRE2/HAC1 is involved in IRE1-mediated KAR2 expression

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12 December 2020

Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity

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12 December 2020

VAPB interacts with and modulates the activity of ATF6.

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12 December 2020

Recent advances in research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 gene mutations: neuronal Lewy body-like hyaline inclusions and astrocytic hyaline inclusions

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12 December 2020

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

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12 December 2020

A common founder for amyotrophic lateral sclerosis type 8 (ALS8) in the Brazilian population

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12 December 2020

Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78

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12 December 2020

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

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12 December 2020

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

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12 December 2020

Auto-antibodies against proteins of spinal cord cells in cerebrospinal fluid of patients with amyotrophic lateral sclerosis (ALS)

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12 December 2020

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

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12 December 2020

Magnesium and Calcium Contents in CNS Tissues of Amyotrophic Lateral Sclerosis Patients from the Kii Peninsula, Japan

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12 December 2020

The Saccharomyces cerevisiae SCS2 gene product, a homolog of a synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for inositol metabolism

1 reference

12 December 2020

Glutamate receptors: RNA editing and death of motor neurons

1 reference

12 December 2020

The roles of free radicals in amyotrophic lateral sclerosis: reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids

1 reference

12 December 2020

Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

1 reference

12 December 2020

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

1 reference

12 December 2020

Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins

1 reference

12 December 2020

Atrophic cell processes of large motor neurons in the anterior horn in amyotrophic lateral sclerosis: observation with silver impregnation method

1 reference

12 December 2020

Differential regulation of endoplasmic reticulum structure through VAP-Nir protein interaction

1 reference

12 December 2020

Mutant Cu,Zn superoxide dismutases and familial amyotrophic lateral sclerosis: evaluation of oxidative hypotheses

1 reference

12 December 2020

Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants

1 reference

12 December 2020

Roles of CHOP/GADD153 in endoplasmic reticulum stress

1 reference

12 December 2020

The unfolded protein response: a novel component of the hypoxic stress response in tumors.

1 reference

12 December 2020

Seipinopathy: a novel endoplasmic reticulum stress-associated disease

1 reference

12 December 2020

Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.

1 reference

12 December 2020

Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8)

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12 December 2020

Regulated translation initiation controls stress-induced gene expression in mammalian cells

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12 December 2020

Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.

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12 December 2020

Phase II/III randomized trial of TCH346 in patients with ALS

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12 December 2020

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

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12 December 2020

The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response

1 reference

12 December 2020

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

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12 December 2020

Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia

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12 December 2020

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

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12 December 2020

Amyotrophic lateral sclerosis brain banking: a proposal to standardize protocols and neuropathological diagnostic criteria.

1 reference

12 December 2020

Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder

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12 December 2020

XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice.

1 reference

12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme

1 reference

12 December 2020

Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam

1 reference

12 December 2020

ALS: a disease of motor neurons and their nonneuronal neighbors

1 reference

12 December 2020

Epidemiology of amyotrophic lateral sclerosis.

1 reference

12 December 2020

Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.

1 reference

12 December 2020

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

12 December 2020

Familial amyotrophic lateral sclerosis with a two base pair deletion in superoxide dismutase 1: gene multisystem degeneration with intracytoplasmic hyaline inclusions in astrocytes.

1 reference

12 December 2020

Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum.

1 reference

12 December 2020

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

1 reference

12 December 2020

Aberrantly increased hydrophobicity shared by mutants of Cu,Zn-superoxide dismutase in familial amyotrophic lateral sclerosis.

1 reference

12 December 2020

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

1 reference

12 December 2020

DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)

1 reference

12 December 2020

SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model

1 reference

12 December 2020

Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

1 reference

12 December 2020

Phosphorylation of neurofilament proteins and localization of axonal swellings in motor neuron disease

1 reference

12 December 2020

Cloning and sequence of the SCS2 gene, which can suppress the defect of INO1 expression in an inositol auxotrophic mutant of Saccharomyces cerevisiae

1 reference

12 December 2020

A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response

1 reference

12 December 2020

Aggregation of ubiquitin and a mutant ALS-linked SOD1 protein correlate with disease progression and fragmentation of the Golgi apparatus

1 reference

12 December 2020

Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice

1 reference

12 December 2020

Morphometry of spinal motor neurons in amyotrophic lateral sclerosis with special reference to chromatolysis and intracytoplasmic inclusion bodies

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12 December 2020

Mammalian stress response: induction of the glucose-regulated protein family

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12 December 2020

Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells

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12 December 2020

Setting the standards: quality control in the secretory pathway

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12 December 2020

Activation of the unfolded protein response by deltaF508 CFTR.

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12 December 2020

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

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12 December 2020

Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis

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12 December 2020

ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis.

1 reference

12 December 2020

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

1 reference

12 December 2020

Unraveling the mechanisms involved in motor neuron degeneration in ALS

1 reference

12 December 2020

Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria

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12 December 2020

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

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12 December 2020

IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae

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12 December 2020

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

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12 December 2020

ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB.

1 reference

12 December 2020

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

1 reference

12 December 2020

Human cytomegalovirus infection activates and regulates the unfolded protein response

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12 December 2020

Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model

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12 December 2020

Deleterious role of superoxide dismutase in the mitochondrial intermembrane space

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12 December 2020

Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate

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12 December 2020

Heterodimer formation of wild-type and amyotrophic lateral sclerosis-causing mutant Cu/Zn-superoxide dismutase induces toxicity independent of protein aggregation

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12 December 2020

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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12 December 2020

The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease

1 reference

12 December 2020

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

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12 December 2020

How transmembrane proteins sense endoplasmic reticulum stress

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12 December 2020

Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis

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12 December 2020

Trial of celecoxib in amyotrophic lateral sclerosis

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12 December 2020

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

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12 December 2020

Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT

1 reference

12 December 2020

Inflammation in amyotrophic lateral sclerosis spinal cord and brain is mediated by activated macrophages, mast cells and T cells.

1 reference

12 December 2020

Activation of an unfolded protein response during differentiation of antibody-secreting B cells.

1 reference

12 December 2020

Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity

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12 December 2020

Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD.

1 reference

12 December 2020

Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice.

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12 December 2020

Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis

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12 December 2020

Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3.

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12 December 2020

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

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12 December 2020

Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells.

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12 December 2020

Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex

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12 December 2020

Fragmentation of the Golgi apparatus of motor neurons in amyotrophic lateral sclerosis (ALS). Clinical studies in ALS of Guam and experimental studies in deafferented neurons and in beta,beta'-iminodipropionitrile axonopathy.

1 reference

12 December 2020

Spinal anterior horn cells in sporadic amyotrophic lateral sclerosis show ribosomal detachment from, and cisternal distention of the rough endoplasmic reticulum

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12 December 2020

A VAMP-binding protein from Aplysia required for neurotransmitter release

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12 December 2020

Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis

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12 December 2020

10.1007/S12035-009-8054-3

Identifiers

DOI

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release_5cymolqhjvhp7fnqwapecqud4e

20 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/5cymolqhjvhp7fnqwapecqud4e

24 November 2022

mapped directly with Wikidata item

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