Expression of insulin receptor isoform A and insulin-like growth factor-1 receptor in human acute myelogenous leukemia: effect of the dual-receptor inhibitor BMS-536924 in vitro (Q37389178)

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scientific article published on 29 September 2009

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English	Expression of insulin receptor isoform A and insulin-like growth factor-1 receptor in human acute myelogenous leukemia: effect of the dual-receptor inhibitor BMS-536924 in vitro	scientific article published on 29 September 2009

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Expression of insulin receptor isoform A and insulin-like growth factor-1 receptor in human acute myelogenous leukemia: effect of the dual-receptor inhibitor BMS-536924 in vitro (English)

1 reference

Europe PubMed Central

20 August 2017

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

Charles Erlichman

8

object named as

Charles Erlichman

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Europe PubMed Central

20 August 2017

author name string

Andrea E Wahner Hendrickson

1

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Europe PubMed Central

20 August 2017

Paul Haluska

2

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Europe PubMed Central

20 August 2017

Paula A Schneider

3

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Europe PubMed Central

20 August 2017

David A Loegering

4

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Europe PubMed Central

20 August 2017

Kevin L Peterson

5

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Europe PubMed Central

20 August 2017

Ricardo Attar

6

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Europe PubMed Central

20 August 2017

B Douglas Smith

7

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Europe PubMed Central

20 August 2017

Marco Gottardis

9

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Europe PubMed Central

20 August 2017

Judith E Karp

10

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Europe PubMed Central

20 August 2017

Joan M Carboni

11

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Europe PubMed Central

20 August 2017

Scott H Kaufmann

12

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Europe PubMed Central

20 August 2017

language of work or name

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publication date

29 September 2009

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Europe PubMed Central

20 August 2017

Cancer Research

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Europe PubMed Central

20 August 2017

69

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Europe PubMed Central

20 August 2017

7635-7643

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Europe PubMed Central

20 August 2017

19

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Europe PubMed Central

20 August 2017

Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924

1 reference

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6 September 2017

BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells

1 reference

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The type I insulin-like growth factor receptor pathway: a key player in cancer therapeutic resistance

1 reference

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Disrupting insulin-like growth factor signaling as a potential cancer therapy

1 reference

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IGF-I mediated survival pathways in normal and malignant cells

1 reference

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Mammalian target of rapamycin as a therapeutic target in leukemia

1 reference

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Type I insulin-like growth factor receptor as a therapeutic target in cancer

1 reference

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mTOR, a new therapeutic target in acute myeloid leukemia

1 reference

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Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine

1 reference

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Insulin-like growth factors and neoplasia.

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Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

1 reference

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Insulin signalling and the regulation of glucose and lipid metabolism

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Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia

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The role of insulin-like growth factor I and its receptor in cell growth, transformation, apoptosis, and chemoresistance in solid tumors

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Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

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Ligand-binding properties of the two isoforms of the human insulin receptor

1 reference

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Autocrine insulin-like growth factor-I signaling promotes growth and survival of human acute myeloid leukemia cells via the phosphoinositide 3-kinase/Akt pathway

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In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417.

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Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity

1 reference

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Central role of Fas-associated death domain protein in apoptosis induction by the mitogen-activated protein kinase kinase inhibitor CI-1040 (PD184352) in acute lymphocytic leukemia cells in vitro

1 reference

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A reappraisal of the role of insulin-like growth factor I in the regulation of human hematopoiesis

1 reference

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Insulin-like growth factor-I receptor. Its role in cell proliferation, apoptosis, and tumorigenicity

1 reference

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Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells

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28 September 2017

Polyethylene glycol conjugated insulin-like growth factor binding protein-1 (IGFBP-1) inhibits growth of breast cancer in athymic mice

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Enhancement of human granulopoiesis in vitro by biosynthetic insulin-like growth factor I/somatomedin C and human growth hormone

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Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation

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Receptor binding and mitogenic effects of insulin and insulinlike growth factors I and II for human myeloid leukemic cells

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The insulin-like growth factor 1 receptor is required for the proliferation of hemopoietic cells

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Effects of insulin-like growth factors (IGFs) and IGF receptor antibodies on the proliferation of human breast cancer cells

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Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways.

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Survival of acute myeloid leukemia cells requires PI3 kinase activation

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

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Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of insulin (INS) and insulin-like growth factor-I (IGF-I) in regulating human erythropoiesis. Studies in vitro under serum-free conditions – comparison to other cytokines and growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

12 December 2020

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inferred from PubMed ID database lookup

In vitro effects of insulin-like growth factor-1 (IGF-1) on proliferation and constitutive cytokine secretion by acute myelogenous leukemia blasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive activation of extracellular signal-regulated kinase in human acute leukemias: combined role of activation of MEK, hyperexpression of extracellular signal-regulated kinase, and downregulation of a phosphatase, PAC1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human bone marrow colony growth in agar-gel

1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decrease in IGF-I binding sites on human promyelocytic leukemia cell line (HL-60) with differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of erythropoiesis in vitro by human growth hormone is mediated by insulin-like growth factor I

1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human growth hormone and insulin-like growth factor-1 enhance the proliferation of human leukemic blasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

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based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factors and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

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based on heuristic

inferred from PubMed ID database lookup

The effect of growth hormone and IGF-I on clonogenic growth of hematopoietic cells in leukemic patients during active disease and during remission--a preliminary report

1 reference

https://pubmed.ncbi.nlm.nih.gov/19789352

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based on heuristic

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Identifiers

10.1158/0008-5472.CAN-09-0511

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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