Role of microRNAs in the regulation of drug metabolism and disposition (Q37604383)

21 August 2017

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title

Role of microRNAs in the regulation of drug metabolism and disposition (English)

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21 August 2017

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1 reference

Ai-Ming Yu

1

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PubMed ID

19785514

21 August 2017

language of work or name

English

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publication date

1 December 2009

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Expert Opinion on Drug Metabolism & Toxicology

21 August 2017

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21 August 2017

5

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21 August 2017

12

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21 August 2017

1513-1528

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Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs

21 August 2017

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https://api.crossref.org/works/10.1517%2F17425250903307448

Regulation of hepatic transporters by xenobiotic receptors

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Cytochrome P450 and xenobiotic receptor humanized mice

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Modulation of metabolic enzymes by dietary phytochemicals: a review of mechanisms underlying beneficial versus unfavorable effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Gene regulation by transcription factors and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

The functions of animal microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Mechanisms of gene silencing by double-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Origins and Mechanisms of miRNAs and siRNAs

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

A three-dimensional view of the molecular machinery of RNA interference

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Identification of hundreds of conserved and nonconserved human microRNAs

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Phylogenetic shadowing and computational identification of human microRNA genes

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Most mammalian mRNAs are conserved targets of microRNAs

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Return to the RNAi world: rethinking gene expression and evolution (Nobel Lecture).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Small silencing RNAs: an expanding universe

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNAs play a role in the development of human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNA responses to cellular stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

microRNAs in Adult Rodent Liver Are Refractory to Dioxin Treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Changes of micro-RNA expression in rat liver treated by acetaminophen or carbon tetrachloride--regulating role of micro-RNA for RNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Circulating microRNAs, potential biomarkers for drug-induced liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Long-term morphine treatment decreases the association of mu-opioid receptor (MOR1) mRNA with polysomes through miRNA23b

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Estradiol-regulated microRNAs control estradiol response in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNA expression changes in lymphoblastoid cell lines in response to lithium treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Identification of novel genes coding for small expressed RNAs

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

An extensive class of small RNAs in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNA expression profiles classify human cancers

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNA signatures in human cancers

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNA maturation: stepwise processing and subcellular localization

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Processing of primary microRNAs by the Microprocessor complex

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

The Drosha-DGCR8 complex in primary microRNA processing

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

RNA polymerase III transcribes human microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

21 January 2018

Mammalian mirtron genes

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https://api.crossref.org/works/10.1517%2F17425250903307448

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Intronic microRNA precursors that bypass Drosha processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

A human snoRNA with microRNA-like functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Nuclear export of microRNA precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

P68 RNA helicase unwinds the human let-7 microRNA precursor duplex and is required for let-7-directed silencing of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

The regulatory activity of microRNA* species has substantial influence on microRNA and 3' UTR evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Disruption of GW bodies impairs mammalian RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

A role for the P-body component GW182 in microRNA function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

miR-148 targets human DNMT3b protein coding region

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Principles of microRNA-target recognition

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNAs direct rapid deadenylation of mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Involvement of microRNA in AU-rich element-mediated mRNA instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Inhibition of translational initiation by Let-7 MicroRNA in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Short RNAs repress translation after initiation in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Human let-7a miRNA blocks protein production on actively translating polyribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Evidence that microRNAs are associated with translating messenger RNAs in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

DIANA-microT web server: elucidating microRNA functions through target prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

MicroInspector: a web tool for detection of miRNA binding sites in an RNA sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

21 January 2018

Human MicroRNA targets

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https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNA targets in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Fast and effective prediction of microRNA/target duplexes

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

The role of site accessibility in microRNA target recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Prediction of mammalian microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

A combined computational-experimental approach predicts human microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Prediction of synergistic transcription factors by function conservation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

The widespread impact of mammalian MicroRNAs on mRNA repression and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Small interfering RNA in drug metabolism and transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Systematic identification of microRNA functions by combining target prediction and expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Identification of human microRNA targets from isolated argonaute protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Isolation of microRNA targets by miRNP immunopurification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

A biochemical approach to identifying microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Identification of miRNA targets with stable isotope labeling by amino acids in cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Widespread changes in protein synthesis induced by microRNAs

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

The impact of microRNAs on protein output

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Experimental validation of miRNA targets

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903307448

Sequence-specific inhibition of small RNA function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

A pancreatic islet-specific microRNA regulates insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

A brain-specific microRNA regulates dendritic spine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Cytochrome P450 expression and regulation in CYP3A4/CYP2D6 double transgenic humanized mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Expression of the Human CYP3A4 Gene in the Small Intestine of Transgenic Mice: In Vitro Metabolism and Pharmacokinetics of Midazolam

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Potential role for human cytochrome P450 3A4 in estradiol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

MicroRNAs as therapeutic targets in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

Ethanol exposure induces differential microRNA and target gene expression and teratogenic effects which can be suppressed by folic acid supplementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903307448

10.1517/17425250903307448

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

19785514