Liver X receptor (LXR) and the reproductive system--a potential novel target for therapeutic intervention. (Q37723237)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

review article

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title

Liver X receptor (LXR) and the reproductive system--a potential novel target for therapeutic intervention (English)

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29 January 2020

1

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29 January 2020

2

Andrzej Semczuk

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29 January 2020

publication date

1 January 2010

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29 January 2020

published in

Pharmacological Reports

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29 January 2020

volume

62

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29 January 2020

issue

1

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29 January 2020

page(s)

15-27

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Liver X receptors (LXR) as therapeutic targets in dyslipidemia

29 January 2020

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Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages

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7 January 2021

The effects of meiosis activating sterol on in-vitro maturation and fertilization of human oocytes from stimulated and unstimulated ovaries

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7 January 2021

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7 January 2021

Inhibition of tumor growth and progression of LNCaP prostate cancer cells in athymic mice by androgen and liver X receptor agonist

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Liver X receptors regulate adrenal cholesterol balance

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Control of human luteal steroidogenesis

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7 January 2021

Inhibition of progesterone production in human luteinized granulosa cells treated with LXR agonists

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7 January 2021

Niemann-Pick C1 like 1 gene expression is down-regulated by LXR activators in the intestine

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Nuclear oxysterol receptors, LXRs, are involved in the maintenance of mouse caput epididymidis structure and functions.

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7 January 2021

Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells

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7 January 2021

Minireview: liver X receptor beta: emerging roles in physiology and diseases

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7 January 2021

Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor

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7 January 2021

Human oocyte maturation in vitro is stimulated by meiosis-activating sterol.

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7 January 2021

Meiosis-activating sterol-mediated resumption of meiosis in mouse oocytes in vitro is influenced by protein synthesis inhibition and cholera toxin.

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7 January 2021

Endoglin (CD105) expression is regulated by the liver X receptor alpha (NR1H3) in human trophoblast cell line JAR.

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7 January 2021

Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors

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7 January 2021

Gene-gene interaction between heme oxygenase-1 and liver X receptor-beta and Alzheimer's disease risk

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7 January 2021

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

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7 January 2021

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

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7 January 2021

Physiological differences between human and rat primary hepatocytes in response to liver X receptor activation by 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride (GW3965).

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7 January 2021

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

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7 January 2021

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

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7 January 2021

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

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7 January 2021

Association between liver X receptor alpha gene polymorphisms and risk of metabolic syndrome in French populations

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7 January 2021

Soluble endoglin is an accurate predictor and a pathogenic molecule in pre-eclampsia

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7 January 2021

Effect of rescuing donated immature human oocytes derived after FSH/hCG stimulation following in vitro culture with or without Follicular Fluid Meiosis Activating Sterol (FF-MAS)--an embryo chromosomal and morphological analysis

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7 January 2021

Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta

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7 January 2021

Placental expression of the nuclear receptors for oxysterols LXRalpha and LXRbeta during mouse and human development.

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7 January 2021

A synthetic analogue of meiosis-activating sterol (FF-MAS) is a potent agonist promoting meiotic maturation and preimplantation development of mouse oocytes maturing in vitro

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7 January 2021

Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.

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7 January 2021

Oxysterol nuclear receptor LXRbeta regulates cholesterol homeostasis and contractile function in mouse uterus

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7 January 2021

Absence of nuclear receptors for oxysterols liver X receptor induces ovarian hyperstimulation syndrome in mice.

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7 January 2021

Liver X receptors regulate adrenal steroidogenesis and hypothalamic-pituitary-adrenal feedback.

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7 January 2021

Cholesterol homeostasis and infertility: the liver X receptor connection.

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7 January 2021

Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease.

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7 January 2021

Lipids from oxidized low-density lipoprotein modulate human trophoblast invasion: involvement of nuclear liver X receptors

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7 January 2021

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

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7 January 2021

Cholesterol-metabolizing cytochromes P450

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7 January 2021

Cytochrome P450s and cholesterol homeostasis

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7 January 2021

Cholesterol transport by the placenta: placental liver X receptor activity as a modulator of fetal cholesterol metabolism?

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7 January 2021

Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

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7 January 2021

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

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7 January 2021

Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages

1 reference

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7 January 2021

The liver X receptor-{beta} is essential for maintaining cholesterol homeostasis in the testis.

1 reference

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7 January 2021

Liver X receptors and epididymal epithelium physiology.

1 reference

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7 January 2021

Oxysterols: modulators of cholesterol metabolism and other processes

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7 January 2021

Role of LXRs in control of lipogenesis

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7 January 2021

The ATP-binding cassette transporter 1 mediates lipid efflux from Sertoli cells and influences male fertility.

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7 January 2021

Intrauterine risk factors for precocious atherosclerosis

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7 January 2021

Principal findings from a multicenter trial investigating the safety of follicular-fluid meiosis-activating sterol for in vitro maturation of human cumulus-enclosed oocytes.

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7 January 2021

Reduced fertility and inability of oocytes to resume meiosis in mice deficient of the Lxr genes.

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7 January 2021

Human endothelial cells of the placental barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1.

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https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5

7 January 2021

Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages

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7 January 2021

Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility

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7 January 2021

Regulation of cholesterologenesis by the oxysterol receptor, LXRalpha.

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7 January 2021

27-Hydroxylation of 7- and 8-dehydrocholesterol in Smith-Lemli-Opitz syndrome: a novel metabolic pathway.

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7 January 2021

Liver X receptors mediate inhibition of hCG secretion in a human placental trophoblast cell line

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7 January 2021

LXR, a nuclear receptor that defines a distinct retinoid response pathway

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7 January 2021

Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis

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7 January 2021

Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands.

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7 January 2021

Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.

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7 January 2021

10.1016/S1734-1140(10)70239-5

Identifiers

DOI

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29 January 2020

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