Genome-wide association studies and type 2 diabetes (Q37857564)

24 August 2017

1 reference

title

Genome-wide association studies and type 2 diabetes (English)

1 reference

genome-wide association study

24 August 2017

0 references

0 references

2

Inês Barroso

0 references

Eleanor Wheeler

series ordinal

1

object named as

Eleanor Wheeler

0 references

publication date

1 March 2011

1 reference

Briefings in functional genomics

24 August 2017

1 reference

24 August 2017

10

1 reference

24 August 2017

52-60

1 reference

24 August 2017

2

1 reference

Global estimates of the prevalence of diabetes for 2010 and 2030

24 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Type 2 diabetes in the young: the evolving epidemic: the international diabetes federation consensus workshop

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Clinical presentation of type 2 diabetes mellitus in children and adolescents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Genetics of Type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance--a population-based twin study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Monogenic diabetes in the young, pharmacogenetics and relevance to multifactorial forms of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Linkage and association studies of the susceptibility genes for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Meta-analysis of 23 type 2 diabetes linkage studies from the International Type 2 Diabetes Linkage Analysis Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Common variants in WFS1 confer risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

The future of genetic studies of complex human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A haplotype map of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Global variation in copy number in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Origins and functional impact of copy number variation in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

The road to genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

PLINK: a tool set for whole-genome association and population-based linkage analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Estimation of the multiple testing burden for genomewide association studies of nearly all common variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A genome-wide association study identifies novel risk loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Genotype imputation for genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Identification of new genetic risk variants for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Variants in MTNR1B influence fasting glucose levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A common variant of HMGA2 is associated with adult and childhood height in the general population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

New common variants affecting susceptibility to basal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Common variants at 30 loci contribute to polygenic dyslipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Parental origin of sequence variants associated with complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Hundreds of variants clustered in genomic loci and biological pathways affect human height

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Clinical risk factors, DNA variants, and the development of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Genotype score in addition to common risk factors for prediction of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Building genetic scores to predict risk of complex diseases in humans: is it possible?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Effect of sulphonylurea treatment on glycaemic control is related to TCF7L2 genotype in patients with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A second generation human haplotype map of over 3.1 million SNPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Functional genomics complements quantitative genetics in identifying disease-gene associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

A novel adaptive method for the analysis of next-generation sequencing data to detect complex trait associations with rare variants due to gene main effects and interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

Type 2 diabetes: new genes, new understanding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR008

21 January 2018

Identifiers

DOI

10.1093/BFGP/ELR008

1 reference

24 August 2017

1 reference

PubMed ID

21436302