Induction and activation of the p53 pathway: a role for the protein kinase CK2? (Q37902541)

25 August 2017

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title

Induction and activation of the p53 pathway: a role for the protein kinase CK2? (English)

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25 August 2017

David W Meek

1

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25 August 2017

Miranda Cox

series ordinal

2

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25 August 2017

publication date

19 July 2011

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Molecular and Cellular Biochemistry

25 August 2017

published in

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25 August 2017

volume

356

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25 August 2017

issue

1-2

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25 August 2017

page(s)

133-138

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Transcriptional control of human p53-regulated genes

25 August 2017

cites work

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Blinded by the Light: The Growing Complexity of p53

21 January 2018

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Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

21 January 2018

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Addiction to protein kinase CK2: a common denominator of diverse cancer cells?

21 January 2018

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CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy

21 January 2018

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One-thousand-and-one substrates of protein kinase CK2?

21 January 2018

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CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response

21 January 2018

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A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1

21 January 2018

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Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

21 January 2018

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Posttranslational modification of p53: cooperative integrators of function

21 January 2018

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Regulation of the DNA binding of p53 by its interaction with protein kinase CK2.

21 January 2018

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Regulation of p53 mediated transactivation by the beta-subunit of protein kinase CK2.

21 January 2018

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Wild-type p53 inhibits protein kinase CK2 activity

21 January 2018

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Regulation of the specific DNA binding function of p53

21 January 2018

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Mutation of the casein kinase II phosphorylation site abolishes the anti-proliferative activity of p53.

21 January 2018

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Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.

21 January 2018

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Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas

21 January 2018

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The absence of Ser389 phosphorylation in p53 affects the basal gene expression level of many p53-dependent genes and alters the biphasic response to UV exposure in mouse embryonic fibroblasts.

21 January 2018

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Mutation at Ser392 specifically sensitizes mutant p53H175 to mdm2-mediated degradation.

21 January 2018

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p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389.

21 January 2018

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The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro

21 January 2018

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Cdk9 phosphorylates p53 on serine 392 independently of CKII.

21 January 2018

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Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation

21 January 2018

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Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389

21 January 2018

1 reference

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Phosphorylation site interdependence of human p53 post-translational modifications in response to stress

21 January 2018

1 reference

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ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-0966-3

Phosphorylation of serine 392 in p53 is a common and integral event during p53 induction by diverse stimuli

21 January 2018

1 reference

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E1A signaling to p53 involves the p19(ARF) tumor suppressor

21 January 2018

1 reference

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Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis

21 January 2018

1 reference

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Mapping of phosphomonoester and apparent phosphodiester bonds of the oncogene product p53 from simian virus 40-transformed 3T3 cells

21 January 2018

1 reference

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Stress-induced activation of protein kinase CK2 by direct interaction with p38 mitogen-activated protein kinase

21 January 2018

1 reference

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Human herpesvirus 6B induces phosphorylation of p53 in its regulatory domain by a CK2- and p38-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-0966-3

Protein kinase CK2-dependent regulation of p53 function: evidence that the phosphorylation status of the serine 386 (CK2) site of p53 is constitutive and stable

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-0966-3

Identification of a CK2 phosphorylation site in mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-0966-3

Hypophosphorylation of Mdm2 augments p53 stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-0966-3

CK1alpha plays a central role in mediating MDM2 control of p53 and E2F-1 protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-0966-3

Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-0966-3

The regulation of MDM2 by multisite phosphorylation--opportunities for molecular-based intervention to target tumours?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-0966-3

Protein kinase CK1delta phosphorylates key sites in the acidic domain of murine double-minute clone 2 protein (MDM2) that regulate p53 turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-011-0966-3

21 January 2018

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12 December 2020

CDK9 phosphorylates p53 on serine residues 33, 315 and 392

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12 December 2020

Phosphorylation of Serine 392 Stabilizes the Tetramer Formation of Tumor Suppressor Protein p53

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12 December 2020

Association of casein kinase II with immunopurified p53.

1 reference

12 December 2020

When mutants gain new powers: news from the mutant p53 field.

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12 December 2020

The p38MAPK inhibitor SB203580 alleviates ultraviolet-induced phosphorylation at serine 389 but not serine 15 and activation of p53

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12 December 2020

DNA damage triggers DRB-resistant phosphorylation of human p53 at the CK2 site

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12 December 2020

SnapShot: p53 posttranslational modifications

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12 December 2020

The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.

1 reference

12 December 2020

10.1007/S11010-011-0966-3

Identifiers

DOI

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25 August 2017

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