The clinical and therapeutic implications of cancer stem cell biology (Q37909375)

25 August 2017

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title

The clinical and therapeutic implications of cancer stem cell biology (English)

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25 August 2017

main subject

neoplastic stem cells

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7

Rodolfo Montironi

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25 August 2017

1

Liang Cheng

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25 August 2017

Antonio Lopez-Beltran

6

object named as

Antonio Lopez-Beltran

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25 August 2017

Riley Alexander

2

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25 August 2017

Shaobo Zhang

3

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25 August 2017

Chong-Xian Pan

4

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25 August 2017

Gregory T MacLennan

5

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25 August 2017

publication date

1 July 2011

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Expert Review of Anticancer Therapy

25 August 2017

published in

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25 August 2017

volume

11

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25 August 2017

issue

7

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25 August 2017

page(s)

1131-1143

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

25 August 2017

cites work

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

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The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

21 January 2018

1 reference

Characterization of clonogenic multiple myeloma cells

21 January 2018

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Identification of human brain tumour initiating cells

21 January 2018

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Prospective identification of tumorigenic prostate cancer stem cells

21 January 2018

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Cancerous stem cells can arise from pediatric brain tumors

21 January 2018

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

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A tumorigenic subpopulation with stem cell properties in melanomas

21 January 2018

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Prostate cancer stem cells.

21 January 2018

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Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance

21 January 2018

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Identification of gastric cancer stem cells using the cell surface marker CD44.

21 January 2018

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Implications of cancer stem cells in the treatment of cancer

21 January 2018

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Characterization of a side population of cancer cells from human gastrointestinal system

21 January 2018

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Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness

21 January 2018

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Cancer stem cells: redefining the paradigm of cancer treatment strategies

21 January 2018

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21 January 2018

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Epidermal growth factor receptor and Ink4a/Arf

21 January 2018

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Stem cells, cancer, and cancer stem cells

21 January 2018

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Efficient tumour formation by single human melanoma cells

21 January 2018

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Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer.

21 January 2018

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Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction

21 January 2018

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Mechanisms controlling pathogenesis and survival of leukemic stem cells

21 January 2018

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Cells of origin in cancer

21 January 2018

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Direct isolation of human central nervous system stem cells

21 January 2018

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Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

21 January 2018

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The multiple roles of PTEN in tumor suppression

21 January 2018

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

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PTEN, stem cells, and cancer stem cells

21 January 2018

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Molecular definition of breast tumor heterogeneity

21 January 2018

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Precancerous stem cells have the potential for both benign and malignant differentiation

21 January 2018

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Cancer stem cells: the lessons from pre-cancerous stem cells

21 January 2018

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Precancerous stem cells can serve as tumor vasculogenic progenitors

21 January 2018

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Liver stem cells and hepatocellular carcinoma

21 January 2018

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21 January 2018

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Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype

21 January 2018

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Prospective identification of tumorigenic breast cancer cells

21 January 2018

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Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

21 January 2018

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CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells

21 January 2018

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Molecular genetic evidence for the independent origin of multifocal papillary tumors in patients with papillary renal cell carcinomas

21 January 2018

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Clonal origin of lymph node metastases in bladder carcinoma

21 January 2018

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Identical allelic losses in mature teratoma and other histologic components of malignant mixed germ cell tumors of the testis

21 January 2018

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Hedgehog signalling in prostate regeneration, neoplasia and metastasis

21 January 2018

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A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer

21 January 2018

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Significance of micrometastasis in bone marrow and blood of operable breast cancer patients: research tool or clinical application?

21 January 2018

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Tumor metastasis: mechanistic insights and clinical challenges

21 January 2018

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Beyond tumorigenesis: cancer stem cells in metastasis

21 January 2018

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Is the hypoxia-inducible factor pathway important in gastric cancer?

21 January 2018

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Involvement of chemokine receptors in breast cancer metastasis

21 January 2018

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Niche-to-niche migration of bone-marrow-derived cells

21 January 2018

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The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

21 January 2018

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Tumour stem cells and drug resistance

21 January 2018

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Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study

21 January 2018

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

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Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer

21 January 2018

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Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells

21 January 2018

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Cancer stem cells in radiation resistance.

21 January 2018

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Cancer stem cell: target for anti-cancer therapy

21 January 2018

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Prostate cancer stem cells: a new target for therapy

21 January 2018

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Radiation resistance in breast cancer: are CD44+/CD24-/proteosome low/PKH26+ cells to blame?

21 January 2018

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Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis

21 January 2018

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A perivascular niche for brain tumor stem cells

21 January 2018

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Why therapeutic response may not prolong the life of a cancer patient: selection for oncogenic resistance

21 January 2018

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Stem cell marker CD133 affects clinical outcome in glioma patients.

21 January 2018

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BCR/ABL kinase inhibition by imatinib mesylate enhances MAP kinase activity in chronic myelogenous leukemia CD34+ cells

21 January 2018

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Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

21 January 2018

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Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation

21 January 2018

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Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction

21 January 2018

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

21 January 2018

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A multidrug resistance transporter from human MCF-7 breast cancer cells

21 January 2018

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Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia

21 January 2018

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Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells

21 January 2018

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MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models

21 January 2018

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The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells

21 January 2018

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Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

21 January 2018

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Targeting cancer stem cells.

21 January 2018

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Cancer stem cells in solid tumors

21 January 2018

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Differentiation versus maturation of neoplastic hematopoietic cells: an important distinction

21 January 2018

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Monoclonal antibodies to the myeloid stem cells: therapeutic implications of CMA-676, a humanized anti-CD33 antibody calicheamicin conjugate

21 January 2018

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131I-anti-CD45 antibody plus busulfan and cyclophosphamide before allogeneic hematopoietic cell transplantation for treatment of acute myeloid leukemia in first remission.

21 January 2018

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Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice.

21 January 2018

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Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.

21 January 2018

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Effects of the EGFR/HER2 kinase inhibitor GW572016 on EGFR- and HER2-overexpressing breast cancer cell line proliferation, radiosensitization, and resistance

21 January 2018

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

21 January 2018

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Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

21 January 2018

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Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

21 January 2018

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Dynamics and potential impact of the immune response to chronic myelogenous leukemia

21 January 2018

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Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity

21 January 2018

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Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis

21 January 2018

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Neoplastic stem cells: a novel therapeutic target in clinical oncology

21 January 2018

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Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species

21 January 2018

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Identification of selective inhibitors of cancer stem cells by high-throughput screening

21 January 2018

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Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

21 January 2018

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Small molecule modulation of Smoothened activity

21 January 2018

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Small molecules in stem cell self-renewal and differentiation

21 January 2018

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Somatic stem cells and the kinetics of mutagenesis and carcinogenesis

21 January 2018

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DNA repair defects in stem cell function and aging

21 January 2018

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Stem cells find their niche

21 January 2018

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The stem-cell niche theory: lessons from flies

21 January 2018

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Normal stem cells and cancer stem cells: the niche matters

21 January 2018

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Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial

21 January 2018

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Circulating tumor cells as prognostic factor for distant metastases and survival in patients with primary uveal melanoma.

21 January 2018

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Metastatic patterns in adenocarcinoma

21 January 2018

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Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

21 January 2018

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Location, location, location: the cancer stem cell niche

21 January 2018

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Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor

21 January 2018

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Cancer stem cell niche: the place to be

21 January 2018

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Making a tumour's bed: glioblastoma stem cells and the vascular niche.

21 January 2018

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Hit 'em where they live: targeting the cancer stem cell niche

21 January 2018

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Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice

21 January 2018

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Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models

21 January 2018

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Socializing with the neighbors: stem cells and their niche

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERA.11.82

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25 August 2017

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