New pathways and mechanisms regulating and responding to Delta-like ligand 4-Notch signalling in tumour angiogenesis (Q37958937)

25 August 2017

New pathways and mechanisms regulating and responding to Delta-like ligand 4-Notch signalling in tumour angiogenesis (English)

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25 August 2017

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25 August 2017

Chern Ein Oon

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publication date

1 December 2011

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Biochemical Society Transactions

25 August 2017

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25 August 2017

39

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25 August 2017

6

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25 August 2017

1612-1618

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Notch signaling in the vasculature

25 August 2017

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https://api.crossref.org/works/10.1042%2FBST20110721

Regulation of vascular morphogenesis by Notch signaling

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Angiogenesis: a team effort coordinated by notch.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Molecular differentiation and specialization of vascular beds.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Vascular morphogenesis: a Wnt for every vessel?

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Control of endothelial sprouting by a Tel-CtBP complex

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Bone marrow-derived endothelial progenitors expressing Delta-like 4 (Dll4) regulate tumor angiogenesis.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Dynamics of endothelial cell behavior in sprouting angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

VEGFRs and Notch: a dynamic collaboration in vascular patterning

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Notch1 controls macrophage recruitment and Notch signaling is activated at sites of endothelial cell anastomosis during retinal angiogenesis in mice

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Therapeutic antibody targeting of individual Notch receptors

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Targeting DLL4 in tumors shows preclinical activity but potentially significant toxicity

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Delta-like ligand 4-notch blockade and tumor radiation response

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Impact of exploratory biomarkers on the treatment effect of bevacizumab in metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Biomarkers to predict the clinical efficacy of bevacizumab in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

VEGF and Notch signaling: the yin and yang of angiogenic sprouting

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Blockade of delta-like ligand 4 signaling inhibits both growth and angiogenesis of pancreatic cancer

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Delta-like ligand 4 plays a critical role in pericyte/vascular smooth muscle cell formation during vasculogenesis and tumor vessel expansion in Ewing's sarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Complementation of human papillomavirus type 16 E6 and E7 by Jagged1-specific Notch1-phosphatidylinositol 3-kinase signaling involves pleiotropic oncogenic functions independent of CBF1;Su(H);Lag-1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Association of high levels of Jagged-1 and Notch-1 expression with poor prognosis in head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Coexpression of Notch1 and NF-kappaB signaling pathway components in human cervical cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

The many facets of Notch ligands

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110721

Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

Chronic DLL4 blockade induces vascular neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110721

21 January 2018

Identifiers

DOI

10.1042/BST20110721

1 reference

release_tzsbcrxj6vdvppt34xjovkrwyq

25 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tzsbcrxj6vdvppt34xjovkrwyq

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

22103496

1 reference

PubMed ID

22103496