VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis (Q37283444)

19 August 2017

9 references

3 April 2019

19 June 2019

20 November 2019

15 December 2019

20 August 2020

26 August 2020

8 February 2021

7 April 2021

13 January 2024

VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis (English)

1 reference

vascular endothelial growth factor A

19 August 2017

2 references

3 April 2019

19 June 2019

1 reference

20 November 2019

1 reference

15 December 2019

1 reference

20 August 2020

1 reference

26 August 2020

1 reference

8 February 2021

1 reference

7 April 2021

1 reference

1 reference

G Thurston

1

1 reference

19 August 2017

J Kitajewski

series ordinal

2

1 reference

19 August 2017

language of work or name

English

0 references

publication date

30 September 2008

1 reference

British Journal of Cancer

19 August 2017

21 October 2008

9 references

3 April 2019

19 June 2019

20 November 2019

15 December 2019

20 August 2020

26 August 2020

8 February 2021

7 April 2021

13 January 2024

10 references

19 August 2017

3 April 2019

19 June 2019

20 November 2019

15 December 2019

20 August 2020

26 August 2020

8 February 2021

7 April 2021

13 January 2024

99

1 reference

19 August 2017

8

1 reference

19 August 2017

1204-1209

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6604484

19 August 2017

0 references

cites work

A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Modulation of VEGF signalling output by the Notch pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Regulation of vascular morphogenesis by Notch signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

VEGF-targeted cancer therapy strategies: current progress, hurdles and future prospects

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

The biology of vascular endothelial growth factors.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Dosage-sensitive requirement for mouse Dll4 in artery development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Notch signaling in primary endothelial cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Role of angiogenesis in tumor growth and metastasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Notch signaling is required for arterial-venous differentiation during embryonic vascular development.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Notch signaling: from the outside in

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Notch signaling is essential for vascular morphogenesis in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Role of vascular endothelial growth factor in the regulation of angiogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Gridlock signalling pathway fashions the first embryonic artery

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570514

Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJC.6604484

The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18827808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of the vascular endothelial growth factor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vessel remodeling and endothelial cell functions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18827808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.BJC.6604484

1 reference

19 August 2017

1 reference

19 August 2017

1 reference