Regulation of iron homeostasis by microRNAs (Q38017136)

27 August 2017

Regulation of iron homeostasis by microRNAs (English)

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27 August 2017

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Martina U Muckenthaler

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2

object named as

Martina U Muckenthaler

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27 August 2017

Mirco Castoldi

1

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27 August 2017

9 June 2012

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Cellular and Molecular Life Sciences

27 August 2017

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27 August 2017

69

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27 August 2017

3945-3952

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27 August 2017

23

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https://scigraph.springernature.com/pub.10.1007/s00018-012-1031-4

27 August 2017

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MicroRNA genes are transcribed by RNA polymerase II

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Processing of primary microRNAs by the Microprocessor complex

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SMAD proteins control DROSHA-mediated microRNA maturation

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Complex patterns of altered MicroRNA expression during the adenoma-adenocarcinoma sequence for microsatellite-stable colorectal cancer

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In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma

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Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

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An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma

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A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

21 January 2018

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A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA

21 January 2018

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A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?

21 January 2018

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Features of mammalian microRNA promoters emerge from polymerase II chromatin immunoprecipitation data

21 January 2018

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Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region

21 January 2018

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The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

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Heme is involved in microRNA processing

21 January 2018

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DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

21 January 2018

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DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures

21 January 2018

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Structure of the dimerization domain of DiGeorge Critical Region 8

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Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing.

21 January 2018

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LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

21 January 2018

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Hepcidin, a urinary antimicrobial peptide synthesized in the liver

21 January 2018

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

21 January 2018

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Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis

21 January 2018

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Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

21 January 2018

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Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

21 January 2018

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A mouse model of juvenile hemochromatosis

21 January 2018

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Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

21 January 2018

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The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

21 January 2018

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Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis

21 January 2018

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The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

21 January 2018

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SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression

21 January 2018

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Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network

21 January 2018

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Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins

21 January 2018

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Severity of neurodegeneration correlates with compromise of iron metabolism in mice with iron regulatory protein deficiencies

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Aberrant expression of TfR1/CD71 in thyroid carcinomas identifies a novel potential diagnostic marker and therapeutic target.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

The iron metabolism of neoplastic cells: alterations that facilitate proliferation?

21 January 2018

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Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester

21 January 2018

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miR-320 targets transferrin receptor 1 (CD71) and inhibits cell proliferation

21 January 2018

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Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function

21 January 2018

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Iron-dependent regulation of the divalent metal ion transporter

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Expression of the two mRNA isoforms of the iron transporter Nramp2/DMTI in mice and function of the iron responsive element

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Regulation of divalent metal transporter 1 (DMT1) non-IRE isoform by the microRNA Let-7d in erythroid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Hypoxia-inducible factor-2α and iron absorptive gene expression in Belgrade rat intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Role of ferritin alterations in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

miR-200 enhances mouse breast cancer cell colonization to form distant metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Altered hepatic BMP signaling pathway in human HFE hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Primary biliary cirrhosis is associated with altered hepatic microRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Downregulation of miR-122 in the rodent and human hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

miR-122, a paradigm for the role of microRNAs in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Positive and negative modulation of viral and cellular mRNAs by liver-specific microRNA miR-122.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Regulation of hepatitis C virus by microRNA-122.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Expression of microRNA-451 in normal and thalassemic erythropoiesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid β, novel targets in sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1031-4

The widespread regulation of microRNA biogenesis, function and decay

21 January 2018

1 reference

12 December 2020

MicroRNA biogenesis: isolation and characterization of the microprocessor complex

1 reference

12 December 2020

Ferroportin-mediated iron transport: expression and regulation

1 reference

12 December 2020

Interferon therapy of hepatitis C: molecular insights into success and failure

1 reference

12 December 2020

Pegylated interferon-α induced hypoferremia is associated with the immediate response to treatment in hepatitis C.

1 reference

12 December 2020

Hepatic iron overload and hepatocellular carcinoma

1 reference

12 December 2020

10.1007/S00018-012-1031-4

Identifiers

DOI

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27 August 2017

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PubMed ID

22678662