siRNA: a new approach to target neuropathic pain (Q38051429)

27 August 2017

siRNA: a new approach to target neuropathic pain (English)

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27 August 2017

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Indu Pal Kaur

1

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PubMed ID

23057947

27 August 2017

Gaurav Sharma

series ordinal

2

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27 August 2017

1 December 2012

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27 August 2017

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27 August 2017

26

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27 August 2017

6

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27 August 2017

401-412

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Delivery systems for the direct application of siRNAs to induce RNA interference (RNAi) in vivo

27 August 2017

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

RNA interference technologies and therapeutics: from basic research to products

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

RNAi-based therapeutics-current status, challenges and prospects

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Strategies for silencing human disease using RNA interference

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Cutaneous short-interfering RNA therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Therapeutic potential of RNA interference

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Gene silencing in mammals by small interfering RNAs

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Biogenesis of small RNAs in animals

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Knocking down disease with siRNAs

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Delivery of RNA interference triggers to sensory neurons in vivo using herpes simplex virus

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

RNA interference: from gene silencing to gene-specific therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

The molecular dynamics of pain control

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Neuropathic pain: emerging treatments

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

New targets for neuropathic pain therapeutics

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Molecular aspects of pain research

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Neuropathic pain: is the end of suffering starting in the gene therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Cellular and Molecular Mechanisms of Pain

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Potential applications of siRNA for pain therapy

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Central delivery of Dicer-substrate siRNA: a direct application for pain research

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

siRNA relieves chronic neuropathic pain

21 January 2018

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https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Harnessing in vivo siRNA delivery for drug discovery and therapeutic development

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Genetic contributions to clinical pain and analgesia: avoiding pitfalls in genetic research

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

The vanilloid receptor: a molecular gateway to the pain pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Engineering an endomorphin-2 gene for use in neuropathic pain therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Relationship of axonal voltage-gated sodium channel 1.8 (NaV1.8) mRNA accumulation to sciatic nerve injury-induced painful neuropathy in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Small interfering RNA-mediated selective knockdown of Na(V)1.8 tetrodotoxin-resistant sodium channel reverses mechanical allodynia in neuropathic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Design and evaluation of small interfering RNAs that target expression of the N-methyl-D-aspartate receptor NR1 subunit gene in the spinal cord dorsal horn.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

siRNA-mediated knockdown of the NR1 subunit gene of the NMDA receptor attenuates formalin-induced pain behaviors in adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Effect of NMDA NR2B antagonist on neuropathic pain in two spinal cord injury models.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

NR2B subunit of NMDA receptor at nucleus accumbens is involved in morphine rewarding effect by siRNA study.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Antinociceptive potentiation and attenuation of tolerance by intrathecal β-arrestin 2 small interfering RNA in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Protein kinase C in pain: involvement of multiple isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Intrathecal lentiviral-mediated RNA interference targeting PKCγ attenuates chronic constriction injury-induced neuropathic pain in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Identification of differentially expressed proteins in the spinal cord of neuropathic pain models with PKCgamma silence by proteomic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Tibia tumor-induced cancer pain involves spinal p38 mitogen-activated protein kinase activation via TLR4-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

A critical role for p38 map kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

FM1-43 is a permeant blocker of mechanosensitive ion channels in sensory neurons and inhibits behavioural responses to mechanical stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Gene therapy targeting nuclear factor-kappaB: towards clinical application in inflammatory diseases and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

The IKK-NF-kappaB pathway: a source for novel molecular drug targets in pain therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

NF-kappaBp65-specific siRNA inhibits expression of genes of COX-2, NOS-2 and MMP-9 in rat IL-1beta-induced and TNF-alpha-induced chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Glycine transporter inhibitors as a novel drug discovery strategy for neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Upregulation of Ca(v)3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

HSV-mediated expression of interleukin-4 in dorsal root ganglion neurons reduces neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Silencing the Kir4.1 potassium channel subunit in satellite glial cells of the rat trigeminal ganglion results in pain-like behavior in the absence of nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Peripherally delivered glutamic acid decarboxylase gene therapy for spinal cord injury pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

A paracrine paradigm for in vivo gene therapy in the central nervous system: treatment of chronic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

ASIC3, a sensor of acidic and primary inflammatory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Recent advances of siRNA delivery by nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Knocking down barriers: advances in siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Lipid-mediated gene delivery to the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Stability study of unmodified siRNA and relevance to clinical use.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

ATP requirements and small interfering RNA structure in the RNA interference pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Gene manipulation through the use of small interfering RNA (siRNA): from in vitro to in vivo applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

Strategies for in vivo delivery of siRNAs: recent progress

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11634380-000000000-00000

10.2165/11634380-000000000-00000

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference

PubMed ID

23057947