Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes (Q38086766)

28 August 2017

Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes (English)

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28 August 2017

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Susan E Ozanne

3

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author name string

Ionel Sandovici

series ordinal

1

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PubMed ID

23463236

28 August 2017

Constanze M Hammerle

series ordinal

2

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PubMed ID

23463236

28 August 2017

Miguel Constância

series ordinal

4

1 reference

28 August 2017

6 March 2013

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Cellular and Molecular Life Sciences

28 August 2017

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28 August 2017

70

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28 August 2017

1575-1595

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28 August 2017

9

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https://scigraph.springernature.com/pub.10.1007/s00018-013-1297-1

28 August 2017

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21 January 2018

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Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus.

21 January 2018

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Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes

21 January 2018

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Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription

21 January 2018

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Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Intrauterine programming of the endocrine pancreas

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Epigenetic differences arise during the lifetime of monozygotic twins

21 January 2018

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21 January 2018

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Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context

21 January 2018

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Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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An imprinted locus associated with transient neonatal diabetes mellitus

21 January 2018

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A conserved imprinting control region at the HYMAI/ZAC domain is implicated in transient neonatal diabetes mellitus.

21 January 2018

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21 January 2018

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21 January 2018

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Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

21 January 2018

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Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets

21 January 2018

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Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes

21 January 2018

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21 January 2018

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Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood

21 January 2018

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21 January 2018

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Epigenetic responses to environmental change and their evolutionary implications

21 January 2018

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Histone methyl transferases and demethylases; can they link metabolism and transcription?

21 January 2018

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21 January 2018

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Pre- and postnatal methyl deficiency in the rat differentially alters glucose homeostasis

21 January 2018

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21 January 2018

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The role of sirtuins in the control of metabolic homeostasis

21 January 2018

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ATP-citrate lyase links cellular metabolism to histone acetylation

21 January 2018

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A metabolic throttle regulates the epigenetic state of rDNA.

21 January 2018

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21 January 2018

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Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

21 January 2018

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Connecting threads: epigenetics and metabolism

21 January 2018

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The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon

21 January 2018

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Effects of long-term exposure to nicotinamide and sodium butyrate on growth, viability, and the function of clonal insulin secreting cells

21 January 2018

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Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism.

21 January 2018

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Modification of histones by sugar β-N-acetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).

21 January 2018

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Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells

21 January 2018

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DNA demethylation dynamics

21 January 2018

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Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress

21 January 2018

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Chromatin modifications and their function

21 January 2018

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SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

21 January 2018

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Early low protein diet aggravates unbalance between antioxidant enzymes leading to islet dysfunction

21 January 2018

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Poor maternal nutrition leads to alterations in oxidative stress, antioxidant defense capacity, and markers of fibrosis in rat islets: potential underlying mechanisms for development of the diabetic phenotype in later life

21 January 2018

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Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndrome.

21 January 2018

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Alterations of NADPH oxidase activity in rat pancreatic islets induced by a high-fat diet.

21 January 2018

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A role for glutathione peroxidase in protecting pancreatic beta cells against oxidative stress in a model of glucose toxicity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1297-1

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

21 January 2018

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Heritable individual-specific and allele-specific chromatin signatures in humans

21 January 2018

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Glucose tolerance in adults after prenatal exposure to famine

21 January 2018

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Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1.

21 January 2018

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12 December 2020

Epigenetics and the environment: emerging patterns and implications

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Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline

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Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells

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The logic linking protein acetylation and metabolism

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Bittersweet memories: linking metabolism to epigenetics through O-GlcNAcylation

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Poor maternal nutrition followed by accelerated postnatal growth leads to telomere shortening and increased markers of cell senescence in rat islets

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12 December 2020

Chromatin-remodeling factors allow differentiation of bone marrow cells into insulin-producing cells

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12 December 2020

Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring

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12 December 2020

Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat.

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Mapping of INS promoter interactions reveals its role in long-range regulation of SYT8 transcription

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Mechanisms of polycomb gene silencing: knowns and unknowns

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GlcNAcylation of histone H2B facilitates its monoubiquitination

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Independent influence of age on basal insulin secretion in nondiabetic humans. European Group for the Study of Insulin Resistance

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Elevated O-linked N-acetylglucosamine metabolism in pancreatic beta-cells

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Beta-cell growth and regeneration: replication is only part of the story

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12 December 2020

10.1007/S00018-013-1297-1

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23463236