Prohibitin ligands in cell death and survival: mode of action and therapeutic potential (Q38092225)

28 August 2017

Prohibitin ligands in cell death and survival: mode of action and therapeutic potential (English)

1 reference

28 August 2017

1 reference

Frédéric Thuaud

1

1 reference

28 August 2017

Nigel Ribeiro

series ordinal

2

1 reference

28 August 2017

Canan G Nebigil

series ordinal

3

1 reference

28 August 2017

Laurent Désaubry

series ordinal

4

1 reference

28 August 2017

1 March 2013

1 reference

28 August 2017

Chemistry and Biology

1 reference

28 August 2017

20

1 reference

28 August 2017

316-331

1 reference

28 August 2017

3

1 reference

Proteomic analysis of mitochondrial proteins in cardiomyocytes from chronic stressed rat

28 August 2017

1 reference

12 December 2020

Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model

1 reference

12 December 2020

Formation of membrane-bound ring complexes by prohibitins in mitochondria

1 reference

12 December 2020

Altered O-GlcNAc modification and phosphorylation of mitochondrial proteins in myoblast cells exposed to high glucose.

1 reference

12 December 2020

Histone deacetylase inhibitors and neurodegenerative disorders: holding the promise

1 reference

12 December 2020

Structural organization of mitochondrial human complex I: role of the ND4 and ND5 mitochondria-encoded subunits and interaction with prohibitin

1 reference

12 December 2020

Akt binds prohibitin 2 and relieves its repression of MyoD and muscle differentiation

1 reference

12 December 2020

Potential biomarkers for ischemic heart damage identified in mitochondrial proteins by comparative proteomics

1 reference

12 December 2020

The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein

1 reference

12 December 2020

Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes.

1 reference

12 December 2020

Mitochondrial-nuclear communication by prohibitin shuttling under oxidative stress

1 reference

12 December 2020

Chemistry and biology of rocaglamides (= flavaglines) and related derivatives from aglaia species (meliaceae)

1 reference

12 December 2020

Altering chemosensitivity by modulating translation elongation

1 reference

12 December 2020

Flavaglines alleviate doxorubicin cardiotoxicity: implication of Hsp27

1 reference

12 December 2020

Prohibitin attenuates insulin-stimulated glucose and fatty acid oxidation in adipose tissue by inhibition of pyruvate carboxylase.

1 reference

12 December 2020

Mitochondrial proteomics analysis of tumorigenic and metastatic breast cancer markers

1 reference

12 December 2020

Dual targeting of the cyclin/Rb/E2F and mitochondrial pathways in mantle cell lymphoma with the translation inhibitor silvestrol.

1 reference

12 December 2020

Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer

1 reference

12 December 2020

Identification of prohibitin as a Chikungunya virus receptor protein

1 reference

12 December 2020

Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients

1 reference

12 December 2020

Two-dimensional electrophoretic analysis of mixed lineage kinase 2 N-terminal domain binding proteins

1 reference

12 December 2020

Loss of transgelin in repeated bouts of ulcerative colitis-induced colon carcinogenesis.

1 reference

12 December 2020

Interleukin-6 transcriptionally regulates prohibitin expression in intestinal epithelial cells

1 reference

12 December 2020

Loss of prohibitin membrane scaffolds impairs mitochondrial architecture and leads to tau hyperphosphorylation and neurodegeneration

1 reference

12 December 2020

Protein profiling the effects of in vitro hyperoxic exposure on fetal rabbit lung

1 reference

12 December 2020

Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function

1 reference

12 December 2020

Prohibitin interacts with phosphatidylinositol 3,4,5-triphosphate (PIP3) and modulates insulin signaling

1 reference

12 December 2020

Rocaglamide breaks TRAIL resistance in HTLV-1-associated adult T-cell leukemia/lymphoma by translational suppression of c-FLIP expression

1 reference

12 December 2020

Proteomic analysis of expression and protein interactions in a 6-hydroxydopamine-induced rat brain lesion model

1 reference

12 December 2020

Raf kinases in cancer-roles and therapeutic opportunities

1 reference

12 December 2020

Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma

1 reference

12 December 2020

Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases

1 reference

12 December 2020

Regulation of Syk by phosphorylation on serine in the linker insert

1 reference

12 December 2020

Localization of prohibitin in the nuclear matrix and alteration of its expression during differentiation of human neuroblastoma SK-N-SH cells induced by retinoic acid

1 reference

12 December 2020

Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication

1 reference

12 December 2020

Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling

1 reference

12 December 2020

Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA.

1 reference

12 December 2020

Radical-free biology of oxidative stress

1 reference

12 December 2020

Differential immunization identifies PHB1/PHB2 as blood-borne tumor antigens

1 reference

12 December 2020

Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol

1 reference

12 December 2020

Raf activation by Ras and promotion of cellular metastasis require phosphorylation of prohibitin in the raft domain of the plasma membrane.

1 reference

12 December 2020

Prohibitin 1 modulates mitochondrial stress-related autophagy in human colonic epithelial cells

1 reference

12 December 2020

Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseases

1 reference

12 December 2020

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action

1 reference

12 December 2020

PHB2 interacts with RNF2 and represses CP2c-stimulated transcription

1 reference

12 December 2020

An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens

1 reference

12 December 2020

Vi polysaccharide of Salmonella typhi targets the prohibitin family of molecules in intestinal epithelial cells and suppresses early inflammatory responses

1 reference

12 December 2020

Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris

1 reference

12 December 2020

eIF4F suppression in breast cancer affects maintenance and progression

1 reference

12 December 2020

Flavaglines: a group of efficient growth inhibitors block cell cycle progression and induce apoptosis in colorectal cancer cells

1 reference

12 December 2020

Rescue of paclitaxel sensitivity by repression of Prohibitin1 in drug-resistant cancer cells

1 reference

12 December 2020

Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes

1 reference

12 December 2020

Prohibitin protects against oxidative stress-induced cell injury in cultured neonatal cardiomyocyte

1 reference

12 December 2020

Tumor suppression by the prohibitin gene 3'untranslated region RNA in human breast cancer

1 reference

12 December 2020

Raf family kinases: old dogs have learned new tricks

1 reference

12 December 2020

Insulin induced phosphorylation of prohibitin at tyrosine 114 recruits Shp1.

1 reference

12 December 2020

Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins.

1 reference

12 December 2020

Peptide designed to elicit apoptosis in adipose tissue endothelium reduces food intake and body weight

1 reference

12 December 2020

The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities

1 reference

12 December 2020

The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells.

1 reference

12 December 2020

Flavaglines as potent anticancer and cytoprotective agents

1 reference

12 December 2020

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

1 reference

12 December 2020

MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin

1 reference

12 December 2020

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

1 reference

12 December 2020

Akt2 is implicated in skeletal muscle differentiation and specifically binds Prohibitin2/REA.

1 reference

12 December 2020

The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo

1 reference

12 December 2020

Cardiac phosphoproteome reveals cell signaling events involved in doxorubicin cardiotoxicity.

1 reference

12 December 2020

Prohibitin has an important role in adipocyte differentiation

1 reference

12 December 2020

Prohibitin1 acts as a neural crest specifier in Xenopus development by repressing the transcription factor E2F1.

1 reference

12 December 2020

Activation of the lifespan regulator p66Shc through reversible disulfide bond formation

1 reference

12 December 2020

A structure for the yeast prohibitin complex: Structure prediction and evidence from chemical crosslinking and mass spectrometry.

1 reference

12 December 2020

The role of prohibitin in cell signaling.

1 reference

12 December 2020

The mitochondrial PHB complex: roles in mitochondrial respiratory complex assembly, ageing and degenerative disease

1 reference

12 December 2020

A synthetic derivative of the natural product rocaglaol is a potent inhibitor of cytokine-mediated signaling and shows neuroprotective activity in vitro and in animal models of Parkinson's disease and traumatic brain injury.

1 reference

12 December 2020

Apoptosis of rat granulosa cells after staurosporine and serum withdrawal is suppressed by adenovirus-directed overexpression of prohibitin

1 reference

12 December 2020

Identification of staphylococcal lipoteichoic acid-binding proteins in human serum by high-resolution LTQ-Orbitrap mass spectrometry

1 reference

12 December 2020

Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells

1 reference

12 December 2020

Identification and characterization of prohibitin as a receptor protein mediating DENV-2 entry into insect cells

1 reference

12 December 2020

Prohibitin is a novel regulator of antioxidant response that attenuates colonic inflammation in mice

1 reference

12 December 2020

Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12.

1 reference

12 December 2020

Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration

1 reference

12 December 2020

Synthesis and SAR of sulfonyl- and phosphoryl amidine compounds as anti-resorptive agents.

1 reference

12 December 2020

Novel flavaglines displaying improved cytotoxicity.

1 reference

12 December 2020

EZH2 regulates the transcription of estrogen-responsive genes through association with REA, an estrogen receptor corepressor

1 reference

12 December 2020

Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites

1 reference

12 December 2020

Chemical affinity matrix-based identification of prohibitin as a binding protein to anti-resorptive sulfonyl amidine compounds

1 reference

12 December 2020

A putative coiled-coil domain of prohibitin is sufficient to repress E2F1-mediated transcription and induce apoptosis

1 reference

12 December 2020

Camptothecin induces nuclear export of prohibitin preferentially in transformed cells through a CRM-1-dependent mechanism

1 reference

12 December 2020

SLP-2 interacts with prohibitins in the mitochondrial inner membrane and contributes to their stability.

1 reference

12 December 2020

Silvestrol regulates G2/M checkpoint genes independent of p53 activity.

1 reference

12 December 2020

Recombinant viral capsid protein VP1 suppresses migration and invasion of human cervical cancer by modulating phosphorylated prohibitin in lipid rafts

1 reference

12 December 2020

Exercise affects energy metabolism and neural plasticity-related proteins in the hippocampus as revealed by proteomic analysis.

1 reference

12 December 2020

Next generation oncology drug development: opportunities and challenges

1 reference

12 December 2020

Marine natural product aurilide activates the OPA1-mediated apoptosis by binding to prohibitin

1 reference

12 December 2020

Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata

1 reference

12 December 2020

Prohibitin, an evolutionarily conserved intracellular protein that blocks DNA synthesis in normal fibroblasts and HeLa cells

1 reference

12 December 2020

Nuclear accumulation of prohibitin 1 in osteoarthritic chondrocytes down-regulates PITX1 expression

1 reference

12 December 2020

Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria

1 reference

12 December 2020

Skp2B overexpression alters a prohibitin-p53 axis and the transcription of PAPP-A, the protease of insulin-like growth factor binding protein 4

1 reference

12 December 2020

Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth

1 reference

12 December 2020

Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.

1 reference

12 December 2020

Prohibitin and prohibitone are contained in high-molecular weight complexes and interact with alpha-actinin and annexin A2

1 reference

12 December 2020

Prohibitin Induces the Transcriptional Activity of p53 and Is Exported from the Nucleus upon Apoptotic Signaling

1 reference

12 December 2020

Increased oxidative stress and decreased antioxidant defenses in mucosa of inflammatory bowel disease

1 reference

12 December 2020

Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

1 reference

12 December 2020

Molecular modeling of prohibitin domains

1 reference

12 December 2020

Nitric oxide-associated protein 1 (NOA1) is necessary for oxygen-dependent regulation of mitochondrial respiratory complexes.

1 reference

12 December 2020

Recent advances in the biology and chemistry of the flavaglines

1 reference

12 December 2020

A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection.

1 reference

12 December 2020

Prohibitin inhibits tumor necrosis factor alpha-induced nuclear factor-kappa B nuclear translocation via the novel mechanism of decreasing importin alpha3 expression

1 reference

12 December 2020

The natural anticancer compounds rocaglamides inhibit the Raf-MEK-ERK pathway by targeting prohibitin 1 and 2

1 reference

12 December 2020

Comparative proteomic studies on the pathogenesis of human ulcerative colitis

1 reference

12 December 2020

Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors

1 reference

12 December 2020

Intramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40.

1 reference

12 December 2020

Identification of core components and transient interactors of the peroxisomal importomer by dual-track stable isotope labeling with amino acids in cell culture analysis

1 reference

12 December 2020

Prohibitin binds to C3 and enhances complement activation

1 reference

12 December 2020

Lipid rafts association and anti-apoptotic function of prohibitin in ultraviolet B light-irradiated HaCaT keratinocytes

1 reference

12 December 2020

CaMK IV phosphorylates prohibitin 2 and regulates prohibitin 2-mediated repression of MEF2 transcription

1 reference

12 December 2020

Leishmania cell surface prohibitin: role in host-parasite interaction.

1 reference

12 December 2020

Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids.

1 reference

12 December 2020

Cytostatic mechanism and antitumor potential of novel 1H-cyclopenta[b]benzofuran lignans isolated from Aglaia elliptica.

1 reference

12 December 2020

Palmitoylation of prohibitin at cysteine 69 facilitates its membrane translocation and interaction with Eps 15 homology domain protein 2 (EHD2).

1 reference

12 December 2020

Prohibitin interacts with RNF2 and regulates E2F1 function via dual pathways.

1 reference

12 December 2020

Prohibitin regulates TGF-beta induced apoptosis as a downstream effector of Smad-dependent and -independent signaling

1 reference

12 December 2020

Activity-guided isolation of cytotoxic constituents from the bark of Aglaia crassinervia collected in Indonesia

1 reference

12 December 2020

Androgen-regulated processing of the oncomir miR-27a, which targets Prohibitin in prostate cancer.

1 reference

12 December 2020

The phagosome proteome: insight into phagosome functions

1 reference

12 December 2020

Dissection of melanogenesis with small molecules identifies prohibitin as a regulator

1 reference

12 December 2020

Rocaglamide sensitizes leukemic T cells to activation-induced cell death by differential regulation of CD95L and c-FLIP expression

1 reference

12 December 2020

Prohibitin protects against oxidative stress in intestinal epithelial cells.

1 reference

12 December 2020

Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease

1 reference

12 December 2020

Prohibitin, a protein downregulated by androgens, represses androgen receptor activity

1 reference

12 December 2020

Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation

1 reference

12 December 2020

α-Dystrobrevin distribution and association with other proteins in human promyelocytic NB4 cells treated for granulocytic differentiation

1 reference

12 December 2020

Functional clustering of metastasis proteins describes plastic adaptation resources of breast-cancer cells to new microenvironments

1 reference

12 December 2020

Prohibitin attenuates colitis-associated tumorigenesis in mice by modulating p53 and STAT3 apoptotic responses

1 reference

12 December 2020

Rocaglamide derivatives are potent inhibitors of NF-kappa B activation in T-cells

1 reference

12 December 2020

Expression of prohibitins on the surface of activated T cells

1 reference

12 December 2020

Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock

1 reference

12 December 2020

A repressive role for prohibitin in estrogen signaling.

1 reference

12 December 2020

Interaction between O-GlcNAc modification and tyrosine phosphorylation of prohibitin: implication for a novel binary switch

1 reference

12 December 2020

Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence

1 reference

12 December 2020

Rapamycin is a neuroprotective treatment for traumatic brain injury.

1 reference

12 December 2020

Prohibitin (PHB) acts as a potent survival factor against ceramide induced apoptosis in rat granulosa cells

1 reference

12 December 2020

Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells.

1 reference

12 December 2020

Skp2B stimulates mammary gland development by inhibiting REA, the repressor of the estrogen receptor

1 reference

12 December 2020

Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

1 reference

12 December 2020

Nanoparticle-based therapeutic delivery of prohibitin to the colonic epithelial cells ameliorates acute murine colitis

1 reference

12 December 2020

Prohibitin facilitates cellular senescence by recruiting specific corepressors to inhibit E2F target genes

1 reference

12 December 2020

Targeting histone deacetylases for heart failure

1 reference

12 December 2020

Regulation of the epithelial Mg2+ channel TRPM6 by estrogen and the associated repressor protein of estrogen receptor activity (REA).

1 reference

12 December 2020

Isolation of a cDNA that hybrid selects antiproliferative mRNA from rat liver

1 reference

12 December 2020

Prohibitin as an oxidative stress biomarker in the eye

1 reference

12 December 2020

Prohibitin-1 deficiency promotes inflammation and increases sensitivity to liver injury.

1 reference

12 December 2020

Prohibitin reduces mitochondrial free radical production and protects brain cells from different injury modalities

1 reference

12 December 2020

Increased density of prohibitin-immunoreactive oligodendrocytes in the dorsolateral prefrontal white matter of subjects with schizophrenia suggests extraneuronal roles for the protein in the disease

1 reference

12 December 2020

Rb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signals

1 reference

12 December 2020

Rocaglamide derivatives are immunosuppressive phytochemicals that target NF-AT activity in T cells

1 reference

12 December 2020

Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein

1 reference

12 December 2020

Silvestrol, a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7.

1 reference

12 December 2020

Skp2B attenuates p53 function by inhibiting prohibitin

1 reference

12 December 2020

Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperon, prohibitin, in cells expressing hepatitis C virus core protein

1 reference

12 December 2020

Prohibitin protects against hypoxia-induced H9c2 cardiomyocyte cell death

1 reference

12 December 2020

A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys

1 reference

12 December 2020

Reversal of obesity by targeted ablation of adipose tissue

1 reference

12 December 2020

Prohibitin is expressed in pancreatic beta-cells and protects against oxidative and proapoptotic effects of ethanol.

1 reference

12 December 2020

Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology

1 reference

12 December 2020

10.1016/J.CHEMBIOL.2013.02.006

Identifiers

DOI

1 reference

28 August 2017

0 references

1 reference