Raf kinases in cancer-roles and therapeutic opportunities (Q28237793)

Chemoresistance of endothelial cells induced by basic fibroblast growth factor depends on Raf-1-mediated inhibition of the proapoptotic kinase, ASK1.

Europe PubMed Central

title

Raf kinases in cancer-roles and therapeutic opportunities (English)

0 references

M Baccarini

3

0 references

author name string

G Maurer

series ordinal

1

0 references

B Tarkowski

series ordinal

2

0 references

language of work or name

English

0 references

publication date

11 August 2011

0 references

published in

Oncogene

0 references

volume

30

0 references

issue

32

0 references

page(s)

3477-88

0 references

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Targeting BRAF for patients with melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Tumour cell survival signalling by the ERK1/2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Extracellular signal-regulated kinase-dependent proliferation is mediated through the protein kinase A/B-Raf pathway in human uveal melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Overexpressed Raf-1 and phosphorylated cyclic adenosine 3'-5'-monophosphatate response element-binding protein are early markers for lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

21 January 2018

Telomeres and telomerase

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Akt3 and mutant V600E B-Raf cooperate to promote early melanoma development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor-induced DNA damage in vitro and in vivo in human multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Does basal cell carcinoma belong to the spectrum of sorafenib-induced epithelial skin cancers?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Oncogenic Braf induces melanocyte senescence and melanoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Regulation of Raf-1 by direct feedback phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

The three Es of cancer immunoediting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Transcriptional regulation of telomerase activity: roles of the the Ets transcription factor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf-1 addiction in Ras-induced skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf-1 regulates Rho signaling and cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Mutations of C-RAF are rare in human cancer because C-RAF has a low basal kinase activity compared with B-RAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Ras effector pathways modulate scatter factor-stimulated NF-kappaB signaling and protection against DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Oxidative stress plays a critical role in inactivating mutant BRAF by geldanamycin derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

P53-mediated induction of Cox-2 counteracts p53- or genotoxic stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Tumor regression by targeted gene delivery to the neovasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Over-expression of c-raf-1 proto-oncogene in liver cirrhosis and hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

BRAF inactivation drives aneuploidy by deregulating CRAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

The raf oncogene is associated with a radiation-resistant human laryngeal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Matrix metalloproteinases: regulators of the tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Tumor cell metabolism: cancer's Achilles' heel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Survival signaling by C-RAF: mitochondrial reactive oxygen species and Ca2+ are critical targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Targeting mutant (V600E) B-Raf in melanoma interrupts immunoediting of leukocyte functions and melanoma extravasation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Principles of cancer therapy: oncogene and non-oncogene addiction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Constitutive activation of Raf-1 induces glioma formation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Integrating signals from RTKs to ERK/MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Genomic instability--an evolving hallmark of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Targets of Raf in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Mutant BRAF melanomas--dependence and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Biological challenges of BRAF inhibitor therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

A dimerization-dependent mechanism drives RAF catalytic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Activated Raf-1 causes growth arrest in human small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Differential c-myc, c-jun, c-raf and p53 expression in squamous cell carcinoma of the head and neck: implication in drug and radioresistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

RAF inhibition and induction of cutaneous squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Regulation and role of Raf-1/B-Raf heterodimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Analysis of the transcriptional program induced by Raf in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

The TGFBeta pathway as a therapeutic target in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

B-Raf is required for ERK activation and tumor progression in a mouse model of pancreatic beta-cell carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Sorafenib inhibits non-small cell lung cancer cell growth by targeting B-RAF in KRAS wild-type cells and C-RAF in KRAS mutant cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Activation of NF-kappa B by oncogenic Raf in HEK 293 cells occurs through autocrine recruitment of the stress kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Transforming Growth Factor β1 Is Up-regulated by Activated Raf in Skeletal Myoblasts but Does Not Contribute to the Differentiation-defective Phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Acute promyelocytic leukemia: from highly fatal to highly curable

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

The RAF proteins take centre stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Partner exchange: protein-protein interactions in the Raf pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Loss of RAF kinase inhibitor protein is a somatic event in the pathogenesis of therapy-related acute myeloid leukemias with C-RAF germline mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Senescence of human fibroblasts induced by oncogenic Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Cancer despite immunosurveillance: immunoselection and immunosubversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Activation of Raf by ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Role of Raf in vascular protection from distinct apoptotic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Disruption of tumor cell adhesion promotes angiogenic switch and progression to micrometastasis in RAF-driven murine lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Chromosomal translocations as a mechanism of BRAF activation in two cases of large congenital melanocytic nevi

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160

Raf kinase inhibitory protein (RKIP): a physiological regulator and future therapeutic target

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.160