Insights into B cells and HIV-specific B-cell responses in HIV-infected individuals (Q38114912)

29 August 2017

Insights into B cells and HIV-specific B-cell responses in HIV-infected individuals (English)

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29 August 2017

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2

Anthony S Fauci

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29 August 2017

1

Susan Moir

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29 August 2017

1 July 2013

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29 August 2017

Immunological Reviews

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29 August 2017

254

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29 August 2017

207-224

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29 August 2017

1

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Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

29 August 2017

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Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T Lymphocytes

21 January 2018

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Reference values for B cell subpopulations from infancy to adulthood.

21 January 2018

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Memory B cell function in HIV-infected children-decreased memory B cells despite ART.

21 January 2018

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Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

21 January 2018

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CpG oligonucleotides enhance proliferative and effector responses of B Cells in HIV-infected individuals

21 January 2018

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Normalization of B cell counts and subpopulations after antiretroviral therapy in chronic HIV disease.

21 January 2018

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B cells in early and chronic HIV infection: evidence for preservation of immune function associated with early initiation of antiretroviral therapy

21 January 2018

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Identification and characterization of circulating human transitional B cells

21 January 2018

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B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.

21 January 2018

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Expansion of functionally immature transitional B cells is associated with human-immunodeficient states characterized by impaired humoral immunity.

21 January 2018

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Two overrepresented B cell populations in HIV-infected individuals undergo apoptosis by different mechanisms

21 January 2018

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Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells.

21 January 2018

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Appearance of immature/transitional B cells in HIV-infected individuals with advanced disease: correlation with increased IL-7.

21 January 2018

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HIV-1 induces phenotypic and functional perturbations of B cells in chronically infected individuals

21 January 2018

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Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily

21 January 2018

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Compromised B cell responses to influenza vaccination in HIV-infected individuals.

21 January 2018

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A potential role for interleukin-7 in T-cell homeostasis

21 January 2018

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Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis

21 January 2018

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Idiopathic CD4+ T lymphocytopenia is associated with increases in immature/transitional B cells and serum levels of IL-7

21 January 2018

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IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection

21 January 2018

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IL-7 in human health and disease

21 January 2018

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The impact of active HIV-1 replication on the physiological age-related decline of immature-transitional B-cells in HIV-1 infected children.

21 January 2018

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Concerted effect of lymphopenia, viraemia and T-cell activation on Fas expression of peripheral B cells in HIV-1-infected patients.

21 January 2018

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B-cell subset alterations and correlated factors in HIV-1 infection

21 January 2018

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The impact of B-cell perturbations on pneumococcal conjugate vaccine response in HIV-infected adults

21 January 2018

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Identification of functional human splenic memory B cells by expression of CD148 and CD27.

21 January 2018

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B cells in HIV infection and disease

21 January 2018

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Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy

21 January 2018

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Loss of discrete memory B cell subsets is associated with impaired immunization responses in HIV-1 infection and may be a risk factor for invasive pneumococcal disease.

21 January 2018

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Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen

21 January 2018

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Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

21 January 2018

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The relationship between CD27 negative and positive B cell populations in human peripheral blood

21 January 2018

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Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

21 January 2018

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Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells.

21 January 2018

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Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells

21 January 2018

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Inhibitory receptors on lymphocytes: insights from infections

21 January 2018

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Human peripheral blood B-cell compartments: a crossroad in B-cell traffic.

21 January 2018

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Human poly- and cross-reactive anti-viral antibodies and their impact on protection and pathology

21 January 2018

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Rapid generation of rotavirus-specific human monoclonal antibodies from small-intestinal mucosa.

21 January 2018

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Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion

21 January 2018

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Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques.

21 January 2018

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Dynamics of memory B-cell populations in blood, lymph nodes, and bone marrow during antiretroviral therapy and envelope boosting in simian immunodeficiency virus SIVmac251-infected rhesus macaques

21 January 2018

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Enhancing SIV-specific immunity in vivo by PD-1 blockade

21 January 2018

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B-lymphocyte dysfunction in chronic HIV-1 infection does not prevent cross-clade neutralization breadth.

21 January 2018

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Natural SIV hosts: showing AIDS the door

21 January 2018

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Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts

21 January 2018

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Dynamics of T- and B-lymphocyte turnover in a natural host of simian immunodeficiency virus

21 January 2018

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How can HIV-type-1-Env immunogenicity be improved to facilitate antibody-based vaccine development?

21 January 2018

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Immunoregulatory effects of HIV-1 Nef protein

21 January 2018

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Effect of highly active antiretroviral therapy on biomarkers of B-lymphocyte activation and inflammation

21 January 2018

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Biomarkers of immune dysfunction in HIV.

21 January 2018

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The myeloid cytokine network in AIDS pathogenesis

21 January 2018

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Antibody-mediated modulation of immune responses.

21 January 2018

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21 January 2018

Acute HIV-1 Infection

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Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

21 January 2018

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Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression

21 January 2018

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Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy

21 January 2018

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Maintenance of serological memory by polyclonal activation of human memory B cells.

21 January 2018

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Interleukin-15 receptor α expression in inflammatory bowel disease patients before and after normalization of inflammation with infliximab.

21 January 2018

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Innate control of B cell responses

21 January 2018

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Immune regulatory function of B cells.

21 January 2018

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Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes

21 January 2018

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Restoring function in exhausted CD8 T cells during chronic viral infection

21 January 2018

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

21 January 2018

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Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

21 January 2018

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PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

21 January 2018

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Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

21 January 2018

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Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

21 January 2018

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Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

21 January 2018

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Clonal B cells in patients with hepatitis C virus-associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset.

21 January 2018

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Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion

21 January 2018

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Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies.

21 January 2018

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Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

21 January 2018

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Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors

21 January 2018

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FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling

21 January 2018

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HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy

21 January 2018

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Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection

21 January 2018

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Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection

21 January 2018

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Towards an HIV cure: a global scientific strategy

21 January 2018

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Mechanism of hypergammaglobulinemia by HIV infection: circulating memory B-cell reduction with plasmacytosis.

21 January 2018

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Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection.

21 January 2018

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Primary HIV-1 infection sets the stage for important B lymphocyte dysfunctions

21 January 2018

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Timing of HAART defines the integrity of memory B cells and the longevity of humoral responses in HIV-1 vertically-infected children

21 January 2018

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A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection

21 January 2018

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Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis.

21 January 2018

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Role of lymphoid organs in the pathogenesis of human immunodeficiency virus (HIV) infection

21 January 2018

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Hyperplastic lymphoid tissue in HIV/AIDS: an electron microscopic study

21 January 2018

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Microbial translocation, immune activation, and HIV disease

21 January 2018

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Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses

21 January 2018

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Plasma cell development and survival.

21 January 2018

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Stages in LAV/HTLV-III lymphadenitis. I. Histological and immunohistological classification.

21 January 2018

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Studies on lymphoid tissue from HIV-infected individuals: implications for the design of therapeutic strategies

21 January 2018

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The unenlarged lymph nodes of HIV-1-infected, asymptomatic patients with high CD4 T cell counts are sites for virus replication and CD4 T cell proliferation. The impact of highly active antiretroviral therapy

21 January 2018

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High frequency of virus-specific B lymphocytes in germinal centers of simian-human immunodeficiency virus-infected rhesus monkeys

21 January 2018

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Spatial alterations between CD4(+) T follicular helper, B, and CD8(+) T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape

21 January 2018

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Expansion of HIV-specific T follicular helper cells in chronic HIV infection

21 January 2018

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CD4 T follicular helper cell dynamics during SIV infection

21 January 2018

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Follicular helper CD4 T cells (TFH)

21 January 2018

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CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

21 January 2018

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Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

21 January 2018

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The origins, function, and regulation of T follicular helper cells

21 January 2018

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Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84.

21 January 2018

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

21 January 2018

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Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells

21 January 2018

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PD-1 and CTLA-4 inhibitory cosignaling pathways in HIV infection and the potential for therapeutic intervention

21 January 2018

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Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

21 January 2018

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Bcl6 mediates the development of T follicular helper cells

21 January 2018

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Peanut lectin binding properties of germinal centres of mouse lymphoid tissue.

21 January 2018

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Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

21 January 2018

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Analysis of somatic mutation in five B cell subsets of human tonsil

21 January 2018

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HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

21 January 2018

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Evidence for a pathogenic determinant in HIV-1 Nef involved in B cell dysfunction in HIV/AIDS.

21 January 2018

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B-cell activation and lymphoma in patients with HIV.

21 January 2018

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Lymphoid malignancies: the dark side of B-cell differentiation

21 January 2018

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Microbial translocation in the pathogenesis of HIV infection and AIDS.

21 January 2018

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Tissue-specific B-cell dysfunction and generalized memory B-cell loss during acute SIV infection

21 January 2018

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The immune response during acute HIV-1 infection: clues for vaccine development

21 January 2018

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Broadly neutralizing antiviral antibodies

21 January 2018

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Lack of simian immunodeficiency virus (SIV) specific IgA response in the intestine of SIV infected rhesus macaques

21 January 2018

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Increased immunoglobulin G production by short term cultured duodenal biopsy samples from HIV infected patients

21 January 2018

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Human immunodeficiency virus type 1 infection is associated with significant mucosal inflammation characterized by increased expression of CCR5, CXCR4, and beta-chemokines

21 January 2018

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Regulation of mucosal IgA responses: lessons from primary immunodeficiencies

21 January 2018

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Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses

21 January 2018

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Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies

21 January 2018

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HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design

21 January 2018

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A Blueprint for HIV Vaccine Discovery

21 January 2018

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The establishment of the plasma cell survival niche in the bone marrow

21 January 2018

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Origin and Function of Circulating Plasmablasts during Acute Viral Infections

21 January 2018

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A method for identification of HIV gp140 binding memory B cells in human blood

21 January 2018

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Spontaneous in vitro production of virus-specific antibody by lymphocytes from HIV-infected subjects

21 January 2018

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Human immunodeficiency virus infection induces both polyclonal and virus-specific B cell activation

21 January 2018

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Characterization of plasmablasts in the blood of HIV-infected viremic individuals: evidence for nonspecific immune activation

21 January 2018

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Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

21 January 2018

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Circulating antibody-secreting cells during acute respiratory syncytial virus infection in adults

21 January 2018

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Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans

21 January 2018

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Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

21 January 2018

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Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

21 January 2018

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A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals

21 January 2018

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Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

21 January 2018

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Mechanisms that determine plasma cell lifespan and the duration of humoral immunity.

21 January 2018

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Immunoglobulin responses at the mucosal interface.

21 January 2018

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Humoral immune responses to the human immunodeficiency virus type-1 (HIV-1) in the genital tract compared to other mucosal sites

21 January 2018

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Immune responses to HIV in the female reproductive tract, immunologic parallels with the gastrointestinal tract, and research implications

21 January 2018

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HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: an IgA gene and functional analysis

21 January 2018

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Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice

21 January 2018

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Detection of peripheral HIV-1-specific memory B cells in patients untreated or receiving highly active antiretroviral therapy

21 January 2018

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Selective expansion of HIV-1 envelope glycoprotein-specific B cell subsets recognizing distinct structural elements following immunization

21 January 2018

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Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system.

21 January 2018

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Prospects for an HIV vaccine: leading B cells down the right path

21 January 2018

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9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity

21 January 2018

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Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

21 January 2018

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

21 January 2018

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Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

21 January 2018

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

21 January 2018

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Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

21 January 2018

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Predominant autoantibody production by early human B cell precursors

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/IMR.12067

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29 August 2017

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PubMed ID

23772622