Concise review: genetic dissection of hypoxia signaling pathways in normal and leukemic stem cells (Q38185296)

30 August 2017

Concise review: genetic dissection of hypoxia signaling pathways in normal and leukemic stem cells (English)

1 reference

30 August 2017

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4

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4 June 2020

author name string

Deniz Gezer

1

1 reference

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4 June 2020

Milica Vukovic

2

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4 June 2020

Tomoyoshi Soga

3

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4 June 2020

Kamil R Kranc

5

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4 June 2020

publication date

1 June 2014

1 reference

30 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24496882%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

32

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4 June 2020

issue

6

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4 June 2020

page(s)

1390-1397

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Hematopoiesis: an evolving paradigm for stem cell biology

4 June 2020

cites work

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The hematopoietic stem cell niche.

21 January 2018

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Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia

21 January 2018

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Regulation of the HIF-1alpha level is essential for hematopoietic stem cells

21 January 2018

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Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells

21 January 2018

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The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

21 January 2018

1 reference

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

21 January 2018

1 reference

Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts

21 January 2018

1 reference

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq.

21 January 2018

1 reference

Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis

21 January 2018

1 reference

Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells

21 January 2018

1 reference

Regulation of metabolism by hypoxia-inducible factor 1.

21 January 2018

1 reference

HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells

21 January 2018

1 reference

HIF1α is a regulator of hematopoietic progenitor and stem cell development in hypoxic sites of the mouse embryo.

21 January 2018

1 reference

Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance

21 January 2018

1 reference

HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.

21 January 2018

1 reference

Cited2 is an essential regulator of adult hematopoietic stem cells

21 January 2018

1 reference

HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency

21 January 2018

1 reference

HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress.

21 January 2018

1 reference

Passing the baton: the HIF switch

21 January 2018

1 reference

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

21 January 2018

1 reference

Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway

21 January 2018

1 reference

The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction

21 January 2018

1 reference

Embryonic origin of the adult hematopoietic system: advances and questions.

21 January 2018

1 reference

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

21 January 2018

1 reference

Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins

21 January 2018

1 reference

Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure

21 January 2018

1 reference

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

21 January 2018

1 reference

Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation.

21 January 2018

1 reference

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway

21 January 2018

1 reference

Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF

21 January 2018

1 reference

Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2

21 January 2018

1 reference

The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation

21 January 2018

1 reference

Molecular cloning and chromosomal localization of the human CITED2 gene encoding p35srj/Mrg1.

21 January 2018

1 reference

Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1

21 January 2018

1 reference

The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in mice

21 January 2018

1 reference

The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.

21 January 2018

1 reference

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

21 January 2018

1 reference

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning

21 January 2018

1 reference

Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1α-dependent function

21 January 2018

1 reference

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

21 January 2018

1 reference

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

21 January 2018

1 reference

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

21 January 2018

1 reference

Targeting HIF1α eliminates cancer stem cells in hematological malignancies.

21 January 2018

1 reference

Isocitrate dehydrogenase mutations in leukemia

21 January 2018

1 reference

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.

21 January 2018

1 reference

What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer

21 January 2018

1 reference

(R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible

21 January 2018

1 reference

HIF-1α downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation

21 January 2018

1 reference

Insights into the stem cells of chronic myeloid leukemia

21 January 2018

1 reference

Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming

21 January 2018

1 reference

Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.

21 January 2018

1 reference

The stem cell niches in bone

21 January 2018

1 reference

Endothelial and perivascular cells maintain haematopoietic stem cells

21 January 2018

1 reference

Hypoxia mediates low cell-cycle activity and increases the proportion of long-term-reconstituting hematopoietic stem cells during in vitro culture.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/STEM.1657

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24496882%20AND%20SRC:MED&resulttype=core&format=json

release_42pbakztfnevdmwhkjfvpuq4wy

4 June 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/42pbakztfnevdmwhkjfvpuq4wy

mapped directly with Wikidata item

24 November 2022

based on heuristic

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