Intestinal epithelial cells: regulators of barrier function and immune homeostasis (Q38190874)

30 August 2017

1 reference

title

Intestinal epithelial cells: regulators of barrier function and immune homeostasis (English)

1 reference

30 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24566914%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

David Artis

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24566914%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

publication date

1 March 2014

1 reference

Nature Reviews Immunology

30 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24566914%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24566914%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24566914%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

141-153

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24566914%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nri3608

7 June 2020

exact match

0 references

cites work

Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications

1 reference

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

31 March 2020

1 reference

Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection

31 March 2020

1 reference

Metabolic endotoxemia initiates obesity and insulin resistance

31 March 2020

1 reference

Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment.

31 March 2020

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Innate immunity and intestinal microbiota in the development of Type 1 diabetes

31 March 2020

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Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

31 March 2020

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Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination.

31 March 2020

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Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells

31 March 2020

1 reference

Role of the gut microbiota in immunity and inflammatory disease

31 March 2020

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Interactions between the microbiota and the immune system

31 March 2020

1 reference

The microbiome in infectious disease and inflammation

31 March 2020

1 reference

Reciprocal interactions of the intestinal microbiota and immune system.

31 March 2020

1 reference

Viral interactions with the host and microbiota in the intestine

31 March 2020

1 reference

Organizing cell renewal in the intestine: stem cells, signals and combinatorial control

31 March 2020

1 reference

Stem cells, self-renewal, and differentiation in the intestinal epithelium

31 March 2020

1 reference

Intestinal goblet cells and mucins in health and disease: recent insights and progress

31 March 2020

1 reference

Epithelial antimicrobial defence of the skin and intestine

31 March 2020

1 reference

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

31 March 2020

1 reference

Colorectal cancer in mice genetically deficient in the mucin Muc2

31 March 2020

1 reference

Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

31 March 2020

1 reference

Intestinal trefoil factor confers colonic epithelial resistance to apoptosis

31 March 2020

1 reference

Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway

31 March 2020

1 reference

RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract

31 March 2020

1 reference

Goblet cell-derived resistin-like molecule beta augments CD4+ T cell production of IFN-gamma and infection-induced intestinal inflammation

31 March 2020

1 reference

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

31 March 2020

1 reference

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

31 March 2020

1 reference

The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine

31 March 2020

1 reference

Secreted enteric antimicrobial activity localises to the mucus surface layer.

31 March 2020

1 reference

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

31 March 2020

1 reference

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

31 March 2020

1 reference

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

31 March 2020

1 reference

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

31 March 2020

1 reference

Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response

31 March 2020

1 reference

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

31 March 2020

1 reference

Genetics and pathogenesis of inflammatory bowel disease

31 March 2020

1 reference

Intestinal epithelial autophagy is essential for host defense against invasive bacteria

31 March 2020

1 reference

Paneth cells as a site of origin for intestinal inflammation.

31 March 2020

1 reference

Regulation of the polymeric immunoglobulin receptor and IgA transport: new advances in environmental factors that stimulate pIgR expression and its role in mucosal immunity

31 March 2020

1 reference

Absence of epithelial immunoglobulin A transport, with increased mucosal leakiness, in polymeric immunoglobulin receptor/secretory component-deficient mice

31 March 2020

1 reference

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut.

31 March 2020

1 reference

Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut

31 March 2020

1 reference

Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium

31 March 2020

1 reference

Anatomical basis of tolerance and immunity to intestinal antigens

31 March 2020

1 reference

Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response

31 March 2020

1 reference

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

31 March 2020

1 reference

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

31 March 2020

1 reference

Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement

31 March 2020

1 reference

Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals

31 March 2020

1 reference

Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function.

31 March 2020

1 reference

Inflammasomes in intestinal inflammation and cancer

31 March 2020

1 reference

Integrative inflammasome activity in the regulation of intestinal mucosal immune responses

31 March 2020

1 reference

Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis

31 March 2020

1 reference

RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium

31 March 2020

1 reference

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

31 March 2020

1 reference

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands

31 March 2020

1 reference

Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency

31 March 2020

1 reference

Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C

31 March 2020

1 reference

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

31 March 2020

1 reference

Epithelial NEMO links innate immunity to chronic intestinal inflammation

31 March 2020

1 reference

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

31 March 2020

1 reference

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

31 March 2020

1 reference

The Nlrp3 inflammasome: contributions to intestinal homeostasis

31 March 2020

1 reference

Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases

31 March 2020

1 reference

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair

31 March 2020

1 reference

Bacterial-modulated host immunity and stem cell activation for gut homeostasis

31 March 2020

1 reference

Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila

31 March 2020

1 reference

Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox-mediated generation of reactive oxygen species

31 March 2020

1 reference

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

31 March 2020

1 reference

ERK activation drives intestinal tumorigenesis in Apc(min/+) mice

31 March 2020

1 reference

Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice

31 March 2020

1 reference

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

31 March 2020

1 reference

Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors

31 March 2020

1 reference

The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis.

31 March 2020

1 reference

Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

31 March 2020

1 reference

Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4.

31 March 2020

1 reference

The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.

31 March 2020

1 reference

Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury

31 March 2020

1 reference

NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling

31 March 2020

1 reference

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18

31 March 2020

1 reference

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

31 March 2020

1 reference

Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells

31 March 2020

1 reference

Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells

31 March 2020

1 reference

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis

31 March 2020

1 reference

miR-146a mediates protective innate immune tolerance in the neonate intestine

31 March 2020

1 reference

Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation

31 March 2020

1 reference

Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination.

31 March 2020

1 reference

The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation

31 March 2020

1 reference

Dissecting negative regulation of Toll-like receptor signaling

31 March 2020

1 reference

Beyond pattern recognition: five immune checkpoints for scaling the microbial threat

31 March 2020

1 reference

Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression

31 March 2020

1 reference

Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation.

31 March 2020

1 reference

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

31 March 2020

1 reference

Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition

31 March 2020

1 reference

RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition

31 March 2020

1 reference

The danger model: a renewed sense of self

31 March 2020

1 reference

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

31 March 2020

1 reference

Angiogenins: a new class of microbicidal proteins involved in innate immunity

31 March 2020

1 reference

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

31 March 2020

1 reference

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

31 March 2020

1 reference

Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-κB pathways in intestinal epithelial cells

31 March 2020

1 reference

Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells

31 March 2020

1 reference

Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

31 March 2020

1 reference

Induction of colonic regulatory T cells by indigenous Clostridium species

31 March 2020

1 reference

Commensal-dependent expression of IL-25 regulates the IL-23-IL-17 axis in the intestine.

31 March 2020

1 reference

Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRIL

31 March 2020

1 reference

Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI.

31 March 2020

1 reference

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis.

31 March 2020

1 reference

The puzzle of intestinal lamina propria dendritic cells and macrophages

31 March 2020

1 reference

Origin of the lamina propria dendritic cell network

31 March 2020

1 reference

Intestinal lamina propria dendritic cell subsets have different origin and functions.

31 March 2020

1 reference

Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.

31 March 2020

1 reference

Intestinal macrophages: well educated exceptions from the rule

31 March 2020

1 reference

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions.

31 March 2020

1 reference

Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria.

31 March 2020

1 reference

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

31 March 2020

1 reference

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

31 March 2020

1 reference

Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells

31 March 2020

1 reference

Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing

31 March 2020

1 reference

Retinoic acid imprints gut-homing specificity on T cells

31 March 2020

1 reference

Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans.

31 March 2020

1 reference

Differentiation and homing of IgA-secreting cells

31 March 2020

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CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

31 March 2020

1 reference

Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria

31 March 2020

1 reference

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

31 March 2020

1 reference

Intestinal CX3C chemokine receptor 1(high) (CX3CR1(high)) myeloid cells prevent T-cell-dependent colitis

31 March 2020

1 reference

Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via αvβ1 integrin

31 March 2020

1 reference

IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses

31 March 2020

1 reference

TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation

31 March 2020

1 reference

IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells

31 March 2020

1 reference

Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.

31 March 2020

1 reference

Innate lymphoid cells: emerging insights in development, lineage relationships, and function

31 March 2020

1 reference

Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung

31 March 2020

1 reference

Innate lymphoid cells: balancing immunity, inflammation, and tissue repair in the intestine.

31 March 2020

1 reference

Innate lymphoid cells--how did we miss them?

31 March 2020

1 reference

Development and function of intestinal innate lymphoid cells

31 March 2020

1 reference

Innate lymphoid cells--a proposal for uniform nomenclature

31 March 2020

1 reference

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

31 March 2020

1 reference

Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-γ-producing cells

31 March 2020

1 reference

Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells

31 March 2020

1 reference

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

31 March 2020

1 reference

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

31 March 2020

1 reference

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

31 March 2020

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Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.

31 March 2020

1 reference

An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation

31 March 2020

1 reference

Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation

31 March 2020

1 reference

The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells

31 March 2020

1 reference

Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells

31 March 2020

1 reference

Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

31 March 2020

1 reference

CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut.

31 March 2020

1 reference

Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

31 March 2020

1 reference

Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease

31 March 2020

1 reference

Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model

31 March 2020

1 reference

Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.

31 March 2020

1 reference

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

31 March 2020

1 reference

IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease

31 March 2020

1 reference

IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells

31 March 2020

1 reference

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

31 March 2020

1 reference

Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes

31 March 2020

1 reference

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

31 March 2020

1 reference

MyD88-dependent signaling for IL-15 production plays an important role in maintenance of CD8 alpha alpha TCR alpha beta and TCR gamma delta intestinal intraepithelial lymphocytes.

31 March 2020

1 reference

The light and dark sides of intestinal intraepithelial lymphocytes

31 March 2020

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Dynamic migration of γδ intraepithelial lymphocytes requires occludin

31 March 2020

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Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface

31 March 2020

1 reference

Transcriptional reprogramming of mature CD4⁺ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes

31 March 2020

1 reference

Peripheral tissue surveillance and residency by memory T cells

31 March 2020

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Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets

31 March 2020

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TGF-{beta}-dependent CD103 expression by CD8(+) T cells promotes selective destruction of the host intestinal epithelium during graft-versus-host disease

31 March 2020

1 reference

Mucosal memory CD8⁺ T cells are selected in the periphery by an MHC class I molecule

31 March 2020

1 reference

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation.

31 March 2020

1 reference

A vaccine strategy that protects against genital herpes by establishing local memory T cells

31 March 2020

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Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

31 March 2020

1 reference

The regulation of IgA class switching.

31 March 2020

1 reference

Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells

31 March 2020

1 reference

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

31 March 2020

1 reference

TACI and BAFF-R mediate isotype switching in B cells

31 March 2020

1 reference

Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.

31 March 2020

1 reference

TACI is mutant in common variable immunodeficiency and IgA deficiency

31 March 2020

1 reference

Identification of stem cells in small intestine and colon by marker gene Lgr5

31 March 2020

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Interconversion between intestinal stem cell populations in distinct niches

31 March 2020

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The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations

31 March 2020

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IFN-γ and TNF-α-induced GBP-1 inhibits epithelial cell proliferation through suppression of β-catenin/TCF signaling

31 March 2020

1 reference

Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways

31 March 2020

1 reference

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis

31 March 2020

1 reference

Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease

31 March 2020

1 reference

Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

31 March 2020

1 reference

Active deformation of apoptotic intestinal epithelial cells with adhesion-restricted polarity contributes to apoptotic clearance

31 March 2020

1 reference

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

31 March 2020

1 reference

Intestinal permeability and the prediction of relapse in Crohn's disease

31 March 2020

1 reference

Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis

31 March 2020

1 reference

Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.

31 March 2020

1 reference

Positional specificity of defensin gene expression reveals Paneth cell heterogeneity in mouse small intestine

31 March 2020

1 reference

12 December 2020

Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice.

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12 December 2020

Intestinal permeability test as a predictor of clinical course in Crohn's disease

1 reference

12 December 2020

Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-beta

1 reference

12 December 2020

TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation

1 reference

12 December 2020