From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells. (Q38213433)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847765%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847765%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847765%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

author name string

Farrah C Steinke

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847765%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

publication date

1 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847765%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847765%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

volume

59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847765%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

page(s)

45-55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847765%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

issue

1-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847765%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s12026-014-8545-9

18 March 2020

exact match

0 references

cites work

Regulation of mature T cell responses by the Wnt signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

WNT signalling in the immune system: WNT is spreading its wings

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

TCF1 and beta-catenin regulate T cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

β-catenin/TCF-1 pathway in T cell development and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Wnt/β-catenin signaling and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Notch regulation of early thymocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

On becoming a T cell, a convergence of factors kick it up a Notch along the way.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Multilayered specification of the T-cell lineage fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Signaling in thymic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Transcription control of early B cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

GATA-3 is required for early T lineage progenitor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

A critical role for TCF-1 in T-lineage specification and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

A far downstream enhancer for murine Bcl11b controls its T-cell specific expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

TCF-1 mediates repression of Notch pathway in T lineage-committed early thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

β-Catenin induces T-cell transformation by promoting genomic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

The life and death of DNA-PK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Identification of DNA-dependent protein kinase catalytic subunit as a novel interaction partner of lymphocyte enhancer factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Pre-TCR-induced beta-catenin facilitates traversal through beta-selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Beta-catenin/Tcf determines the outcome of thymic selection in response to alphabetaTCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Beta-catenin regulates positive selection of thymocytes but not lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

CD4-CD8 lineage differentiation: Thpok-ing into the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

RUNX proteins in transcription factor networks that regulate T-cell lineage choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

TOX is required for development of the CD4 T cell lineage gene program

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

beta-Catenin expression enhances generation of mature thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Runx3-mediated transcriptional program in cytotoxic lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Molecular pathogenesis of T-cell leukaemia and lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Molecular basis for the tissue specificity of β-catenin oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Beta-catenin stabilization stalls the transition from double-positive to single-positive stage and predisposes thymocytes to malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

β-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

T cell factor-1 negatively regulates expression of IL-17 family of cytokines and protects mice from experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Critical role of TCF-1 in repression of the IL-17 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

A network of high-mobility group box transcription factors programs innate interleukin-17 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

The Wnt inhibitor secreted Frizzled-Related Protein 1 (sFRP1) promotes human Th17 differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Suppressive regulatory T cell activity is potentiated by glycogen synthase kinase 3{beta} inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Lithium prevents and ameliorates experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Canonical Wnt signaling negatively modulates regulatory T cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Diversity, function, and transcriptional regulation of gut innate lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Innate lymphoid cells--how did we miss them?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Innate lymphoid cells--a proposal for uniform nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Clonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

T cell factor 1 is required for group 2 innate lymphoid cell generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Transcription factor RORα is critical for nuocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

The role of the nuclear hormone receptor RORγt in the development of lymph nodes and Peyer's patches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

IL-17-producing gammadelta T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Alternative memory in the CD8 T cell lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

T cell factor-1 and β-catenin control the development of memory-like CD8 thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Lymphoid enhancer factor interacts with GATA-3 and controls its function in T helper type 2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Nuclear IGF1R is a transcriptional co-activator of LEF1/TCF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Beta-catenin hits chromatin: regulation of Wnt target gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

CBP/p300 are bimodal regulators of Wnt signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Poly(ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

TCF-1 Controls ILC2 and NKp46+ROR t+ Innate Lymphocyte Differentiation and Protection in Intestinal Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8545-9

Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells

21 January 2018

1 reference

12 December 2020

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

1 reference

12 December 2020

The epigenetic landscape of lineage choice: lessons from the heritability of CD4 and CD8 expression

1 reference

12 December 2020

Determining γδ versus αß T cell development.

1 reference

12 December 2020

Redundant functions of TCF-1 and LEF-1 during T and NK cell development, but unique role of TCF-1 for Ly49 NK cell receptor acquisition

1 reference

12 December 2020

Selectively impaired development of intestinal T cell receptor gamma delta+ cells and liver CD4+ NK1+ T cell receptor alpha beta+ cells in T cell factor-1-deficient mice

1 reference

12 December 2020

Tales of the unexpected: Tcf1 functions as a tumor suppressor for leukemias

1 reference

12 December 2020

Notch signaling in the immune system

1 reference

12 December 2020

Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus

1 reference

12 December 2020