The Roles of Lysosomes in Inflammation and Autoimmune Diseases (Q38235294)

31 August 2017

The Roles of Lysosomes in Inflammation and Autoimmune Diseases (English)

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31 August 2017

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Wei Ge

1

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31 August 2017

Dongxu Li

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2

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31 August 2017

Yanpan Gao

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3

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31 August 2017

Xuetao Cao

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4

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31 August 2017

30 July 2014

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International Reviews of Immunology

31 August 2017

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31 August 2017

34

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31 August 2017

415-431

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31 August 2017

5

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On the trail of the glucocorticoid receptor: into the nucleus and back

31 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Crosstalk between the glucocorticoid receptor and other transcription factors: molecular aspects.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

New insights into the anti-inflammatory mechanisms of glucocorticoids: an emerging role for glucocorticoid-receptor-mediated transactivation

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Antiinflammatory action of glucocorticoids--new mechanisms for old drugs

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Glucocorticoid- and mineralocorticoid receptors in microglial cells: the two receptors mediate differential effects of corticosteroids.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Identification of a lysosomal pathway that modulates glucocorticoid signaling and the inflammatory response.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Immunological and inflammatory functions of the interleukin-1 family

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Mechanisms of interleukin-1beta release

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Intracellular trafficking and secretion of inflammatory cytokines

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Regulating secretory lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

SNAREing immunity: the role of SNAREs in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Flightless, secreted through a late endosome/lysosome pathway, binds LPS and dampens cytokine secretion

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Hypoxia enhances lysosomal TNF-alpha degradation in mouse peritoneal macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

21 January 2018

Hypoxia and inflammation

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Evidence for lysosomal exocytosis and release of aggrecan-degrading hydrolases from hypertrophic chondrocytes, in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

The R-SNARE endobrevin/VAMP-8 mediates homotypic fusion of early endosomes and late endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

VAMP-7 mediates vesicular transport from endosomes to lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Late endosome/lysosome-localized Rab7b suppresses TLR9-initiated proinflammatory cytokine and type I IFN production in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Small Rab GTPase Rab7b promotes megakaryocytic differentiation by enhancing IL-6 production and STAT3-GATA-1 association

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

SNX25 regulates TGF-β signaling by enhancing the receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Inflammatory cytokine response to Bacillus anthracis peptidoglycan requires phagocytosis and lysosomal trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Nuclear receptors in inflammation control: repression by GR and beyond.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Immune system irregularities in lysosomal storage disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Lysosomal alpha-galactosidase controls the generation of self lipid antigens for natural killer T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

The lysosomal cysteine proteases in MHC class II antigen presentation

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Dendritic cell function in lupus: Independent contributors or victims of aberrant immune regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Toll-like receptors in systemic autoimmune disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Autoimmunity and the clearance of dead cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Roles of pro- and anti-inflammatory cytokines in the pathogenesis of SLE

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Cytokines as therapeutic targets in SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Cloning and characterization of a lysosomal phospholipase A2, 1-O-acylceramide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Purification and characterization of 1-O-acylceramide synthase, a novel phospholipase A2 with transacylase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Group XV phospholipase A₂, a lysosomal phospholipase A₂.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Autoimmunity through cytokine-induced dendritic cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

New insights into mechanisms of therapeutic effects of antimalarial agents in SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Cathepsin K deficiency in pycnodysostosis results in accumulation of non-digested phagocytosed collagen in fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Cathepsin k is a critical protease in synovial fibroblast-mediated collagen degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Serum cathepsin K levels of patients with longstanding rheumatoid arthritis: correlation with radiological destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

The TNF-alpha transgenic mouse model of inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation evoked by collagen-induced arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

An inhibitor of cathepsin K, icariin suppresses cartilage and bone degradation in mice of collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Targeting cathepsin L (CL) by specific ribozymes decreases CL protein synthesis and cartilage destruction in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Activity of lysosomal exoglycosidases in serum and synovial fluid in patients with chronic Lyme and rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

TNF-alpha and pathologic bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Six-transmembrane epithelial antigen of prostate4 (STEAP4) is a tumor necrosis factor alpha-induced protein that regulates IL-6, IL-8, and cell proliferation in synovium from patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Upregulation of cathepsin S in psoriatic keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Increased expression of CD208 (DC-LAMP) in epidermal keratinocytes of psoriatic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Significance of DC-LAMP and DC-SIGN expression in psoriasis vulgaris lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Cathepsins and their endogenous inhibitors cystatins: expression and modulation in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Expression of cathepsins S and D signals a distinctive biochemical trait in CD34+ hematopoietic stem cells of relapsing-remitting multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Increased expression of cathepsins and obesity-induced proinflammatory cytokines in lacrimal glands of male NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Graves' disease-associated changes in the serum lysosomal glycosidases activity and the glycosaminoglycan content

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

The autoimmunity-related GIMAP5 GTPase is a lysosome-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Cathepsin L inhibition prevents murine autoimmune diabetes via suppression of CD8(+) T cell activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

Regulation of cathepsin G reduces the activation of proinsulin-reactive T cells from type 1 diabetes patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

TNF-alpha-mediated lysosomal permeabilization is FAN and caspase 8/Bid dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2014.936587

10.3109/08830185.2014.936587

21 January 2018

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DOI

1 reference

31 August 2017

1 reference