Programmed necrosis and necroptosis signalling (Q38261258)

1 September 2017

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title

Programmed necrosis and necroptosis signalling (English)

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1 September 2017

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Maria Feoktistova

1

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1 September 2017

Martin Leverkus

series ordinal

2

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1 September 2017

language of work or name

English

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publication date

11 November 2014

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1 September 2017

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1 September 2017

volume

282

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1 September 2017

issue

1

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1 September 2017

page(s)

19-31

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Molecular mechanisms of regulated necrosis

1 September 2017

cites work

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Necroptosis: the release of damage-associated molecular patterns and its physiological relevance

21 January 2018

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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

21 January 2018

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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Molecular mechanisms of necroptosis: an ordered cellular explosion

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Necrostatin-1 suppresses autophagy and apoptosis in mice traumatic brain injury model

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Inhibition of autophagy rescues palmitic acid-induced necroptosis of endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Ferroptosis: an iron-dependent form of nonapoptotic cell death

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC-MAPKs-AP-1 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Smac mimetic primes apoptosis-resistant acute myeloid leukaemia cells for cytarabine-induced cell death by triggering necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation.

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

A tangled web of ubiquitin chains: breaking news in TNF-R1 signaling.

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Toll-like receptor-mediated down-regulation of the deubiquitinase cylindromatosis (CYLD) protects macrophages from necroptosis in wild-derived mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

Cobalt triggers necrotic cell death and atrophy in skeletal C2C12 myotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Structural study of the RIPoptosome core reveals a helical assembly for kinase recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Pick your poison: the Ripoptosome, a cell death platform regulating apoptosis and necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Characterization of the ripoptosome and its components: implications for anti-inflammatory and cancer therapy

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13120

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Stoichiometry of the CD95 death-inducing signaling complex: experimental and modeling evidence for a death effector domain chain model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

IAPs, regulators of innate immunity and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

The caspase-8 modulator c-FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

The role of c-FLIP in modulation of CD95-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95- and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Intrinsic cleavage of receptor-interacting protein kinase-1 by caspase-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

MLKL regulates necrotic plasma membrane permeabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Necrosis-dependent and independent signaling of the RIP kinases in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Fas/CD95-induced chemokines can serve as "find-me" signals for apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Virus inhibition of RIP3-dependent necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

RIPK1- and RIPK3-induced cell death mode is determined by target availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Mechanisms of necroptosis in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Survival function of the FADD-CASPASE-8-cFLIP(L) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

cFLIP regulates skin homeostasis and protects against TNF-induced keratinocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Protective roles for caspase-8 and cFLIP in adult homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

RIPK3-mediated necroptosis promotes donor kidney inflammatory injury and reduces allograft survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Targeting cell death in the reperfused heart: pharmacological approaches for cardioprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Programmed Necrosis: A Prominent Mechanism of Cell Death following Neonatal Brain Injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

Necroptosis, in vivo detection in experimental disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13120

21 January 2018

Identifiers

DOI

10.1111/FEBS.13120

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1 September 2017

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