CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis (Q35009699)

5 August 2017

CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis (English)

1 reference

5 August 2017

1 reference

David M Moquin

1

1 reference

5 August 2017

Thomas McQuade

series ordinal

2

1 reference

5 August 2017

Francis Ka-Ming Chan

series ordinal

3

1 reference

5 August 2017

language of work or name

English

0 references

publication date

2 October 2013

1 reference

5 August 2017

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5 August 2017

8

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5 August 2017

10

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5 August 2017

e76841

1 reference

Creative Commons Attribution 4.0 International

5 August 2017

start time

2 October 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1.

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NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.

8 July 2018

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The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

8 July 2018

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Regulation of NF-κB by deubiquitinases

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Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

8 July 2018

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CLIPR-59 regulates TNF-α-induced apoptosis by controlling ubiquitination of RIP1.

8 July 2018

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The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

8 July 2018

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Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

8 July 2018

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Programmed necrosis: backup to and competitor with apoptosis in the immune system

8 July 2018

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TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

8 July 2018

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Caspase 8 inhibits programmed necrosis by processing CYLD

8 July 2018

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RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts

8 July 2018

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RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

8 July 2018

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RIP3 mediates the embryonic lethality of caspase-8-deficient mice

8 July 2018

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Functional complementation between FADD and RIP1 in embryos and lymphocytes

8 July 2018

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RIP1 comes back to life as a cell death regulator in TNFR1 signaling

8 July 2018

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cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

8 July 2018

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Molecular mechanisms of necroptosis: an ordered cellular explosion

8 July 2018

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Viral cell death inhibitor MC159 enhances innate immunity against vaccinia virus infection

8 July 2018

1 reference

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Going up in flames: necrotic cell injury and inflammatory diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Ubiquitin chain cleavage: CYLD at work

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

TNF-alpha induces two distinct caspase-8 activation pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Regulation of T cell development by the deubiquitinating enzyme CYLD

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788787

The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24098568

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0076841

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference