The beta-cell in type 1 diabetes: What have we learned from proteomic studies? (Q38340362)

2 September 2017

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title

The beta-cell in type 1 diabetes: What have we learned from proteomic studies? (English)

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2 September 2017

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3

Chantal Mathieu

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2 September 2017

4

Lut Overbergh

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2 September 2017

Inne Crèvecoeur

1

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PubMed ID

25641783

2 September 2017

Dieter Rondas

series ordinal

2

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2 September 2017

26 March 2015

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Proteomics - Clinical Applications

2 September 2017

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2 September 2017

9

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2 September 2017

7-8

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2 September 2017

755-766

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Enterovirus infections and insulin dependent diabetes mellitus--evidence for causality.

2 September 2017

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

The role of perforin and granzymes in diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Type 1 diabetes: entering the proteomic era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Initial sequencing and analysis of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Ribosomal proteins. VII. Two-dimensional polyacrylamide gel electrophoresis for fingerprinting of ribosomal proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Difference gel electrophoresis: a single gel method for detecting changes in protein extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Fluorescent two-dimensional difference gel electrophoresis unveils the potential of gel-based proteomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Multiplex proteomic analysis by two-dimensional differential in-gel electrophoresis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Emerging protein array technologies for proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Coupling ultra high-pressure liquid chromatography with mass spectrometry: constraints and possible applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Two-dimensional protein database of human pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Characterization of the human pancreatic islet proteome by two-dimensional LC/MS/MS

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Quantitative proteomic analysis of single pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Two-dimensional gel proteome reference map of INS-1E cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Insulin secretory granule biogenesis. Co-ordinate regulation of the biosynthesis of the majority of constituent proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Proteomics analysis of insulin secretory granules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

The insulin secretory granule as a signaling hub.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Improved characterization of the insulin secretory granule proteomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Sorting and storage during secretory granule biogenesis: looking backward and looking forward

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Mitochondriomics or what makes us breathe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Applied proteomics: mitochondrial proteins and effect on function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

The profile of mitochondrial proteins and their phosphorylation signaling network in INS-1 beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Immune-mediated β-cell death in type 1 diabetes: lessons from human β-cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Advances in our understanding of the pathophysiology of Type 1 diabetes: lessons from the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

The mechanisms of alloxan- and streptozotocin-induced diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

On the pathogenesis of IDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Unraveling the pathogenesis of type 1 diabetes with proteomics: present and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

A human phenome-interactome network of protein complexes implicated in genetic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Glucagon-like peptide-1 protects human islets against cytokine-mediated β-cell dysfunction and death: a proteomic study of the pathways involved

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Anti-apoptotic action of exendin-4 in INS-1 beta cells: comparative protein pattern analysis of isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Novel insights into the global proteome responses of insulin-producing INS-1E cells to different degrees of endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Proteomic technologies for the discovery of type 1 diabetes biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Serological Proteome Analysis (SERPA) as a tool for the identification of new candidate autoantigens in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Clinical applications of diabetes antibody testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Discovery and validation of serum protein changes in type 1 diabetes patients using high throughput two dimensional liquid chromatography-mass spectrometry and immunoassays

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Low leucocyte myeloperoxidase activity in patients with multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Identification of beta-tubulin isoform V as an autoantigen in allergic rhinitis by a proteomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Tubulin is a neuronal target of autoantibodies in Sydenham's chorea

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Identification of a common autoantigenic epitope of protein disulfide isomerase, golgin-160 and voltage-gated potassium channel in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Antibody-based proteomics for human tissue profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Towards a knowledge-based Human Protein Atlas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Posttranslational modifications of proteins in type 1 diabetes: the next step in finding the cure?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Proinsulin-a pathogenic autoantigen in type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

HLA-DR1001 presents "altered-self" peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Chromogranin A is an autoantigen in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Celiac disease: caught between a rock and a hard place

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Chromogranin A is a T cell antigen in human type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Citrullinated glucose-regulated protein 78 is an autoantigen in type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Biogenesis of secretory granules in the trans-Golgi network of neuroendocrine and endocrine cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Proteome Analysis of Interleukin-1 -Induced Changes in Protein Expression in Rat Islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Characterization of discriminant human brain antigenic targets in neuropsychiatric systemic lupus erythematosus using an immunoproteomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Towards a human proteome atlas: High-throughput generation of mono-specific antibodies for tissue profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201400135

21 January 2018

Identifiers

DOI

10.1002/PRCA.201400135

1 reference

2 September 2017

1 reference

PubMed ID

25641783