Advances in our understanding of the pathophysiology of Type&#160;1 diabetes: lessons from the NOD mouse (Q38135862)

29 August 2017

Advances in our understanding of the pathophysiology of Type 1 diabetes: lessons from the NOD mouse (English)

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29 August 2017

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Abhirup Jayasimhan

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29 August 2017

Kristy P Mansour

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2

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29 August 2017

Robyn M Slattery

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29 August 2017

language of work or name

English

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publication date

1 January 2014

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29 August 2017

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29 August 2017

126

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29 August 2017

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29 August 2017

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The NOD mouse: a model of immune dysregulation

29 August 2017

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Genetic control of autoimmune diabetes in the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Interleukin-21 is required for the development of type 1 diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

IL-21 signaling is critical for the development of type I diabetes in the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Viral infection triggers central nervous system autoimmunity via activation of CD8+ T cells expressing dual TCRs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Genes within the Idd5 and Idd9/11 diabetes susceptibility loci affect the pathogenic activity of B cells in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Structure of wild-type and mutant mouse β2-microglobulin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Transgenic rescue implicates beta2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Raised temperature reduces the incidence of diabetes in the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Vitamin D deficiency in early life accelerates Type 1 diabetes in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

No effect of the 1alpha,25-dihydroxyvitamin D3 on beta-cell residual function and insulin requirement in adults with new-onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Dietary proteins as environmental modifiers of type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

A wheat-based, diabetes-promoting diet induces a Th1-type cytokine bias in the gut of NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Diet, gut microbiota and immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Probiotics for the prevention of beta cell autoimmunity in children at genetic risk of type 1 diabetes--the PRODIA study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Diabetes preventive gluten-free diet decreases the number of caecal bacteria in non-obese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Virus infections in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

The "perfect storm" for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Overexpression of class I major histocompatibility complex accompanies insulitis in the non-obese diabetic mouse and is prevented by anti-interferon-gamma antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

In situ characterization of dendritic cells occurring in the islets of nonobese diabetic mice during the development of insulitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Microorganisms and autoimmunity: making the barren field fertile?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Aberrant prostaglandin synthase 2 expression defines an antigen-presenting cell defect for insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Clinical update on the use of immuno modulators (antiCD3, GAD, Diapep277, anti-IL1) in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Defective maturation of myeloid dendritic cell (DC) in NOD mice is controlled by IDD10/17/18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

SUMO wrestling with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Distinct phenotype and function of NK cells in the pancreas of nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

CD107a as a functional marker for the identification of natural killer cell activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

NKG2D blockade prevents autoimmune diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Activation of natural killer cells: underlying molecular mechanisms revealed

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Beta cell MHC class I is a late requirement for diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Checkpoints in the progression of autoimmune disease: lessons from diabetes models

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

B-cell cross-presentation of autologous antigen precipitates diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Loss of intra-islet CD20 expression may complicate efficacy of B-cell-directed type 1 diabetes therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Impaired migration of NOD mouse thymocytes: a fibronectin receptor-related defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Multivectorial abnormal cell migration in the NOD mouse thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

A mechanism for the major histocompatibility complex-linked resistance to autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC gene-controlled near death experience.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

CCR7 deficiency in NOD mice leads to thyroiditis and primary hypothyroidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

CD40 on NOD CD4 T cells contributes to their activation and pathogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

The B7-independent isoform of CTLA-4 functions to regulate autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Transgenic expression of murine chemokine decoy receptor D6 by islets reveals the role of inflammatory CC chemokines in the development of autoimmune diabetes in NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Vascular addressins are induced on islet vessels during insulitis in nonobese diabetic mice and are involved in lymphoid cell binding to islet endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Matrix metalloproteinases, T cell homing and beta-cell mass in type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Persistent infection of human microvascular endothelial cells by coxsackie B viruses induces increased expression of adhesion molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Intercellular adhesion molecule (ICAM-1) inhibition can induce tolerance in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Beta cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabète Insuline Orale group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

T-cell autoantigens in the non-obese diabetic mouse model of autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

T cell recognition of autoantigens in human type 1 diabetes: clinical perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

GAD treatment and insulin secretion in recent-onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Inhibition of autoimmune type 1 diabetes by gastrointestinal helminth infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Th17: the third member of the effector T cell trilogy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Dynamic interaction between T cell-mediated β-cell damage and β-cell repair in the run up to autoimmune diabetes of the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Peripheral CD4loCD40+ auto-aggressive T cell expansion during insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

A unique T cell subset described as CD4loCD40+ T cells (TCD40) in human type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

21 January 2018

Treg in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

A defect in interleukin 12-induced activation and interferon gamma secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Clinical application of NKT cell biology in type I (autoimmune) diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Mediators and mechanisms of pancreatic beta-cell death in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Significant role for Fas in the pathogenesis of autoimmune diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

New and future immunomodulatory therapy in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Analysis of islet inflammation in human type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

An update on the use of NOD mice to study autoimmune (Type 1) diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Pancreatic beta-cell function and immune responses to insulin after administration of intranasal insulin to humans at risk for type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

No effect of oral insulin on residual beta-cell function in recent-onset type I diabetes (the IMDIAB VII). IMDIAB Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Autoreactive T cells in human type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Oral anti-CD3 monoclonal antibody delays diabetes in non-obese diabetic (NOD) mice: effects on pregnancy and offspring--a preliminary report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

The pancreas in human type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Autoantibodies in Type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+CD25+ regulatory T cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with Type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Through Regulation of TCR Expression Levels, an Idd7 Region Gene(s) Interactively Contributes to the Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in Nonobese Diabetic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Prevention of diabetes in non-obese diabetic I-Ak transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120627

21 January 2018

Identifiers

DOI

10.1042/CS20120627

1 reference

29 August 2017

1 reference