The diverse role of RIP kinases in necroptosis and inflammation (Q38530866)

3 September 2017

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title

The diverse role of RIP kinases in necroptosis and inflammation (English)

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Erratum: The diverse role of RIP kinases in necroptosis and inflammation

3 September 2017

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corrigendum / erratum

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Motti Gerlic

3

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John Silke

object named as

John Silke

series ordinal

1

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author name string

James A Rickard

series ordinal

2

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PubMed ID

26086143

3 September 2017

language of work or name

English

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publication date

1 June 2015

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3 September 2017

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3 September 2017

16

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3 September 2017

689-697

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3 September 2017

7

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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

3 September 2017

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

21 January 2018

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Concepts of tissue injury and cell death in inflammation: a historical perspective.

21 January 2018

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An innate sense of danger

21 January 2018

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Fas/CD95-induced chemokines can serve as "find-me" signals for apoptotic cells

21 January 2018

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An evolutionary perspective on apoptosis.

21 January 2018

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Natural adjuvants: endogenous activators of dendritic cells

21 January 2018

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Apoptosis: controlled demolition at the cellular level

21 January 2018

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Activation of the innate immunity in Drosophila by endogenous chromosomal DNA that escaped apoptotic degradation

21 January 2018

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Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation

21 January 2018

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Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

21 January 2018

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21 January 2018

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Pyroptotic death storms and cytopenia

21 January 2018

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The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge

21 January 2018

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Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.

21 January 2018

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The regulation of TNF signalling: what a tangled web we weave

21 January 2018

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Regulation of death receptor signaling by the ubiquitin system

21 January 2018

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Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs

21 January 2018

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HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death.

21 January 2018

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IAP gene deletion and conditional knockout models

21 January 2018

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Death and survival: viral regulation of TNF signaling pathways

21 January 2018

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Masters, marionettes and modulators: intersection of pathogen virulence factors and mammalian death receptor signaling

21 January 2018

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Linear ubiquitination prevents inflammation and regulates immune signalling

21 January 2018

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Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

21 January 2018

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TNF-alpha induces two distinct caspase-8 activation pathways

21 January 2018

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The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

21 January 2018

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Necroptosis induced by RIPK3 requires MLKL but not Drp1.

21 January 2018

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Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

21 January 2018

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Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.

21 January 2018

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Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

21 January 2018

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MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates.

21 January 2018

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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

21 January 2018

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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

21 January 2018

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Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart

21 January 2018

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Caspase-8 serves both apoptotic and nonapoptotic roles

21 January 2018

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FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

21 January 2018

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Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

21 January 2018

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RIP3 mediates the embryonic lethality of caspase-8-deficient mice

21 January 2018

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

21 January 2018

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Functional complementation between FADD and RIP1 in embryos and lymphocytes

21 January 2018

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Survival function of the FADD-CASPASE-8-cFLIP(L) complex

21 January 2018

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FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

21 January 2018

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Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

21 January 2018

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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

21 January 2018

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RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3

21 January 2018

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RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

21 January 2018

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RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition

21 January 2018

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IAPs limit activation of RIP kinases by TNF receptor 1 during development

21 January 2018

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The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis

21 January 2018

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Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis

21 January 2018

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Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

21 January 2018

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Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

21 January 2018

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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

21 January 2018

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RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

21 January 2018

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RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.

21 January 2018

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RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.

21 January 2018

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RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis

21 January 2018

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RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein

21 January 2018

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Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

21 January 2018

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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

21 January 2018

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Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.

21 January 2018

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FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.

21 January 2018

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Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells

21 January 2018

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Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner

21 January 2018

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Necroptosis: the release of damage-associated molecular patterns and its physiological relevance

21 January 2018

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Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases.

21 January 2018

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The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

21 January 2018

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IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

21 January 2018

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Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice.

21 January 2018

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Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis

21 January 2018

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TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

21 January 2018

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RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

21 January 2018

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Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

21 January 2018

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RIPK3-mediated necroptosis promotes donor kidney inflammatory injury and reduces allograft survival.

21 January 2018

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Synchronized renal tubular cell death involves ferroptosis.

21 January 2018

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Necrostatin-1 blocks both RIPK1 and IDO: consequences for the study of cell death in experimental disease models

21 January 2018

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RIP3 induces apoptosis independent of pronecrotic kinase activity

21 January 2018

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A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing

21 January 2018

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Control of life-or-death decisions by RIP1 kinase

21 January 2018

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A FADD-dependent innate immune mechanism in mammalian cells

21 January 2018

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Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosis

21 January 2018

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Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation

21 January 2018

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A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses

21 January 2018

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Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

21 January 2018

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Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1.

21 January 2018

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Virus inhibition of RIP3-dependent necrosis

21 January 2018

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DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

21 January 2018

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Suppression of RIP3-dependent necroptosis by human cytomegalovirus

21 January 2018

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Necroptosis takes place in human immunodeficiency virus type-1 (HIV-1)-infected CD4+ T lymphocytes.

21 January 2018

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Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense

21 January 2018

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RIP1/RIP3 binding to HSV-1 ICP6 initiates necroptosis to restrict virus propagation in mice.

21 January 2018

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Herpes simplex virus suppresses necroptosis in human cells

21 January 2018

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Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

21 January 2018

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Pathogen-mediated proteolysis of the cell death regulator RIPK1 and the host defense modulator RIPK2 in human aortic endothelial cells.

21 January 2018

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Catalytically active Yersinia outer protein P induces cleavage of RIP and caspase-8 at the level of the DISC independently of death receptors in dendritic cells.

21 January 2018

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Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.

21 January 2018

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Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling

21 January 2018

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The death domain kinase RIP protects thymocytes from tumor necrosis factor receptor type 2-induced cell death

21 January 2018

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Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis

21 January 2018

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A novel function of RIP1 in postnatal development and immune homeostasis by protecting against RIP3-dependent necroptosis and FADD-mediated apoptosis

21 January 2018

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Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

21 January 2018

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Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration

21 January 2018

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Programmed necrosis, not apoptosis, is a key mediator of cell loss and DAMP-mediated inflammation in dsRNA-induced retinal degeneration.

21 January 2018

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Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein

21 January 2018

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Protective roles for caspase-8 and cFLIP in adult homeostasis.

21 January 2018

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Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury

21 January 2018

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RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation

21 January 2018

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FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

21 January 2018

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A role of RIP3-mediated macrophage necrosis in atherosclerosis development.

21 January 2018

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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

21 January 2018

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Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI.

21 January 2018

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Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice

21 January 2018

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Necrostatin-1 ameliorates symptoms in R6/2 transgenic mouse model of Huntington's disease

21 January 2018

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Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo.

21 January 2018

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Necrostatin: a potentially novel cardioprotective agent?

21 January 2018

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Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-α-induced shock.

21 January 2018

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Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

21 January 2018

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Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

21 January 2018

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The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

21 January 2018

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12 December 2020

Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways

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12 December 2020

Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product

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12 December 2020

Interleukin-33 biology with potential insights into human diseases

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12 December 2020

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner

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12 December 2020

Anti-TNF therapy, from rationale to standard of care: what lessons has it taught us?

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12 December 2020

Identifiers

DOI

10.1038/NI.3206

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3 September 2017

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PubMed ID

26086143