An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation. (Q38773915)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27135738%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

title

An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation (English)

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3 April 2020

13

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Jeremy M Simon

4

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3 April 2020

author name string

George P Souroullas

1

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3 April 2020

William R Jeck

2

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3 April 2020

Joel S Parker

3

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3 April 2020

Jie-Yu Liu

5

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3 April 2020

Joshiawa Paulk

6

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3 April 2020

Jessie Xiong

7

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3 April 2020

Kelly S Clark

8

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3 April 2020

Yuri Fedoriw

9

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3 April 2020

Jun Qi

10

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3 April 2020

Christin E Burd

11

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3 April 2020

James E Bradner

12

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3 April 2020

language of work or name

English

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publication date

2 May 2016

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3 April 2020

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3 April 2020

volume

22

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3 April 2020

issue

6

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3 April 2020

page(s)

632-640

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Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2

3 April 2020

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6 September 2017

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6 September 2017

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Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

6 September 2017

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6 September 2017

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Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

6 September 2017

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ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

6 September 2017

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Inactivating mutations of acetyltransferase genes in B-cell lymphoma

6 September 2017

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Epigenetic silencing mediated through activated PI3K/AKT signaling in breast cancer

6 September 2017

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Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

6 September 2017

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Somatic p16(INK4a) loss accelerates melanomagenesis

6 September 2017

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6 September 2017

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Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

6 September 2017

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Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus.

6 September 2017

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6 September 2017

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6 September 2017

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MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

6 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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25 September 2017

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25 September 2017

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31 August 2018

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Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.

31 August 2018

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31 August 2018

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Crossref

https://api.crossref.org/works/10.1038%2FNM.4092

Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences

21 January 2018

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

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Characterization of melanocyte-specific inducible Cre recombinase transgenic mice

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27135738

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.4092

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27135738%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27135738%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

PubMed publication ID

27135738

1 reference