Tyrosine hydroxylase (TH), its cofactor tetrahydrobiopterin (BH4), other catecholamine-related enzymes, and their human genes in relation to the drug and gene therapies of Parkinson's disease (PD): historical overview and future prospects (Q38834545)

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scientific article published on 4 August 2016

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English	Tyrosine hydroxylase (TH), its cofactor tetrahydrobiopterin (BH4), other catecholamine-related enzymes, and their human genes in relation to the drug and gene therapies of Parkinson's disease (PD): historical overview and future prospects	scientific article published on 4 August 2016

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

1 reference

Europe PubMed Central

Tyrosine hydroxylase (TH), its cofactor tetrahydrobiopterin (BH4), other catecholamine-related enzymes, and their human genes in relation to the drug and gene therapies of Parkinson's disease (PD): historical overview and future prospects (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Parkinson's disease

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Toshiharu Nagatsu

1

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Ikuko Nagatsu

2

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

publication date

4 August 2016

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Journal of Neural Transmission

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Neuroprotective effects of zonisamide target astrocyte.

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https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

O-Methylation of Epinephrine and Other Catechols in vitro and in vivo

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21 January 2018

cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Transgenic mice express the human phenylethanolamine N-methyltransferase gene in adrenal medulla and retina

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Excretion of dopamine in diseases of basal ganglia.

1 reference

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21 January 2018

Adenovirus in the brain: recent advances of gene therapy for neurodegenerative diseases.

1 reference

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21 January 2018

Increase of Cerebral Catecholamines caused by 3,4-Dihydroxyphenylalanine after Inhibition of Peripheral Decarboxylase

1 reference

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21 January 2018

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

The potentiation of the anti akinetic effect after L-Dopa treatment by an inhibitor of Mao-B, deprenil

1 reference

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21 January 2018

Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Catechol-O-methyltransferase and its inhibitors in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Inherited levels of A and B types of monoamine oxidase activity

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Treatment of parkinsonism with bromocriptine.

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21 January 2018

3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists

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21 January 2018

Beta-carboline analogues of N-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP): endogenous factors underlying idiopathic parkinsonism?

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https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Modification of Parkinsonism--chronic treatment with L-dopa

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https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Localization of the human tyrosine hydroxylase gene to 11p15: gene duplication and evolution of metabolic pathways

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21 January 2018

Dopamine β-hydroxylase: two polymorphisms in linkage disequilibrium at the structural gene DBH associate with biochemical phenotypic variation

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21 January 2018

Tyrosine hydroxylase and regulation of dopamine synthesis

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https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Prolonged maturation culture favors a reduction in the tumorigenicity and the dopaminergic function of human ESC-derived neural cells in a primate model of Parkinson's disease

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21 January 2018

Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation

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21 January 2018

Tyrosine hydroxylase phosphorylation: regulation and consequences

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https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Results from a phase I safety trial of hAADC gene therapy for Parkinson disease

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21 January 2018

Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system

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21 January 2018

Catecholamine Metabolism: A Contemporary View with Implications for Physiology and Medicine

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

The medical treatment of Parkinson disease from James Parkinson to George Cotzias

1 reference

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21 January 2018

Reduction and oxidation of the active site iron in tyrosine hydroxylase: kinetics and specificity

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Regulatory mechanism of tyrosine hydroxylase activity

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Intra-neuronal vesicular uptake of catecholamines is decreased in patients with Lewy body diseases

1 reference

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21 January 2018

Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease

1 reference

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21 January 2018

A vesicular sequestration to oxidative deamination shift in myocardial sympathetic nerves in Parkinson's disease

1 reference

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21 January 2018

Crystal structure of tyrosine hydroxylase at 2.3 A and its implications for inherited neurodegenerative diseases

1 reference

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21 January 2018

A single human gene encoding multiple tyrosine hydroxylases with different predicted functional characteristics

1 reference

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21 January 2018

Tyramine oxidase: A new enzyme system in liver

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Considerations for measuring iron in post-mortem tissue of Parkinson's disease patients.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Species differences in the expression of multiple tyrosine hydroxylase protein isoforms

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Neuroinflammation in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

The Incidence of Parkinson's Disease: A Systematic Review and Meta-Analysis

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Tyrosine hydroxylase deficiency causes progressive encephalopathy and dopa-nonresponsive dystonia.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Primary structure of mouse tyrosine hydroxylase deduced from its cDNA.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Isolation and characterization of a cDNA clone encoding human aromatic L-amino acid decarboxylase

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Tissue-specific alternative splicing of the first exon generates two types of mRNAs in human aromatic L-amino acid decarboxylase

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Increased heterogeneity of tyrosine hydroxylase in humans

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Quantification of mRNA of tyrosine hydroxylase and aromatic L-amino acid decarboxylase in the substantia nigra in Parkinson's disease and schizophrenia

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Human DJ-1-specific Transcriptional Activation of Tyrosine Hydroxylase Gene

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Stimulus-coupled interaction of tyrosine hydroxylase with 14-3-3 proteins.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Multiple receptors for dopamine

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Isolation of a novel cDNA clone for human tyrosine hydroxylase: alternative RNA splicing produces four kinds of mRNA from a single gene

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Tissue-specific and high-level expression of the human tyrosine hydroxylase gene in transgenic mice

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Synaptic integration mediated by striatal cholinergic interneurons in basal ganglia function

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

THE STRUCTURE OF THE PHENYLALANINE-HYDROXYLATION COFACTOR

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

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21 January 2018

Dopamine-beta-hydroxylase and tyrosine hydroxylase immunoreactive neurons in the human brainstem

1 reference

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21 January 2018

Aromatic L-amino acid decarboxylase-immunoreactive structures in human midbrain, pons, and medulla

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Recessively inherited L-DOPA-responsive dystonia caused by a point mutation (Q381K) in the tyrosine hydroxylase gene

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https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Molecular genetics of tyrosine 3-monooxygenase and inherited diseases

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Isolation of a full-length cDNA clone encoding human tyrosine hydroxylase type 3

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https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Structure of the human tyrosine hydroxylase gene: alternative splicing from a single gene accounts for generation of four mRNA types

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Human dopamine beta-hydroxylase gene: two mRNA types having different 3'-terminal regions are produced through alternative polyadenylation

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21 January 2018

Genetic alteration of catecholamine specificity in transgenic mice.

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21 January 2018

Immunotoxin-mediated conditional disruption of specific neurons in transgenic mice.

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21 January 2018

Viral Vectors for Gene Therapy: Translational and Clinical Outlook

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21 January 2018

The metabolism of L-3-0-methyldopa, aprecursor of dopa in man

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21 January 2018

Catecholaminergic systems in stress: structural and molecular genetic approaches.

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21 January 2018

Identification of cDNA clones coding for rat tyrosine hydroxylase antigen

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21 January 2018

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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21 January 2018

Cloning of quail tyrosine hydroxylase: amino acid homology with other hydroxylases discloses functional domains

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21 January 2018

Differential regulation of the human tyrosine hydroxylase isoforms via hierarchical phosphorylation

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21 January 2018

Four isoforms of tyrosine hydroxylase are expressed in human brain

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21 January 2018

Recessively inherited L-DOPA-responsive parkinsonism in infancy caused by a point mutation (L205P) in the tyrosine hydroxylase gene

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21 January 2018

Introduction to Viral Vectors and Other Delivery Methods for Gene Therapy of the Nervous System

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21 January 2018

N-methylation underlying Parkinson's disease.

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21 January 2018

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

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21 January 2018

Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates.

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21 January 2018

Understanding Dopaminergic Cell Death Pathways in Parkinson Disease

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21 January 2018

Early addition of selegiline to L-Dopa treatment is beneficial for patients with Parkinson disease

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21 January 2018

Tyrosine hydroxylase and tryptophan hydroxylase do not form heterotetramers

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21 January 2018

Sandwich enzyme immunoassay of dopamine-?-hydroxylase in cerebrospinal fluid from control and parkinsonian patients

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21 January 2018

Effects of systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to mice on tyrosine hydroxylase, L-3,4-dihydroxyphenylalanine decarboxylase, dopamine beta-hydroxylase, and monoamine oxidase activities in the striatum and hypothala

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

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21 January 2018

Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Direct comparison of autologous and allogeneic transplantation of iPSC-derived neural cells in the brain of a non-human primate

1 reference

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21 January 2018

Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Zonisamide has beneficial effects on Parkinson's disease patients

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Zonisamide improves motor function in Parkinson disease: a randomized, double-blind study

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Genes for human catecholamine-synthesizing enzymes

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https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Isoquinoline neurotoxins in the brain and Parkinson's disease

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21 January 2018

Amine-related neurotoxins in Parkinson's disease: past, present, and future

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21 January 2018

The catecholamine system in health and disease -Relation to tyrosine 3-monooxygenase and other catecholamine-synthesizing enzymes

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Simple photometric assay of dopamine-beta-hydroxylase activity in human blood: useful in clinical chemistry.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Molecular biology of catecholamine-related enzymes in relation to Parkinson's disease.

1 reference

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21 January 2018

Inflammatory process in Parkinson's disease: role for cytokines

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https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Molecular mechanism of the relation of monoamine oxidase B and its inhibitors to Parkinson's disease: possible implications of glial cells

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21 January 2018

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-dopa therapy for Parkinson's disease: past, present, and future

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Pteridines as cofactor or inhibitor of tyrosine hydroxylase.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Phenylethanolamine N-methyltransferase and other enzymes of catecholamine metabolism in human brain

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Immunocytochemical localization of tyrosine hydroxylase, dopamine-?-hydroxylase and phenylethanolamine-N-methyltransferase in the adrenal glands of the frog and rat by a peroxidase-antiperoxidase method

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Specific localization of the guanosine triphosphate (GTP) cyclohydrolase I-immunoreactivity in the human brain

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Role of N-terminus of tyrosine hydroxylase in the biosynthesis of catecholamines

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Dopamine-derived endogenous N-methyl-(R)-salsolinol: its role in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Modulation of monoamine oxidase (MAO) expression in neuropsychiatric disorders: genetic and environmental factors involved in type A MAO expression

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission

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21 January 2018

Isolation and characterization of the human tyrosine hydroxylase gene: identification of 5' alternative splice sites responsible for multiple mRNAs

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21 January 2018

A new splicing variant for human tyrosine hydroxylase in the adrenal medulla

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21 January 2018

iPS cell technologies: significance and applications to CNS regeneration and disease

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21 January 2018

Inactivation of tyrosine hydroxylase in rat striatum by 1-methyl-4-phenylpyridinium ion (MPP+).

1 reference

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21 January 2018

Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial.

1 reference

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21 January 2018

Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial

1 reference

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21 January 2018

Is Parkinson's disease a vesicular dopamine storage disorder? Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum

1 reference

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21 January 2018

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

1 reference

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21 January 2018

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

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21 January 2018

Formation of noradrenaline in the rat brain from the four stereoisomers of 3,4-dihydroxyphenylserine

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Tyrosine hydroxylase activity in caudate nucleus from Parkinson's disease: effects of iron and phosphorylating agents.

1 reference

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21 January 2018

Genomic aspects of sporadic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Comparison of Human Serum Dopamine-β-Hydroxylase Levels by Radioimmunoassay and Enzymatic Assay

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Differential effects of stress on gene transcription factors in catecholaminergic systems

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Molecular regulation of gene expression of catecholamine biosynthetic enzymes by stress: sympathetic ganglia versus adrenal medulla

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Distribution of catechol compounds in human brain

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Molecular cloning of genomic DNA and chromosomal assignment of the gene for human aromatic L-amino acid decarboxylase, the enzyme for catecholamine and serotonin biosynthesis

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Complex molecular regulation of tyrosine hydroxylase

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Tetrahydrobiopterin biosynthesis, regeneration and functions

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

A common point mutation in the tyrosine hydroxylase gene in autosomal recessive L-DOPA-responsive dystonia in the Dutch population

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

A carboxyl terminal leucine zipper is required for tyrosine hydroxylase tetramer formation

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

The relevance of glial monoamine oxidase-B and polyamines to the action of selegiline in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

The therapeutic potential of monoamine oxidase inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Aldehyde dehydrogenase 2 in sporadic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-016-1596-4

21 January 2018

Progress in monoamine oxidase (MAO) research in relation to genetic engineering

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catecholamine metabolism: basic aspects and clinical significance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin is phosphorylated by PINK1 to activate parkin

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly sensitive assay for tyrosine hydroxylase activity by high-performance liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative studies on the structure of human tyrosine hydroxylase with those of the enzyme of various mammals

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical hallmarks of tyrosine hydroxylase deficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The primary structure of human dopamine-beta-hydroxylase: insights into the relationship between the soluble and the membrane-bound forms of the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The occurrence, distribution and physiological role of catecholamines in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histochemical detection of apoptosis in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

End-product inhibition of tyrosine hydroxylase as a possible mechanism for regulation of norepinephrine synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A branch site mutation leading to aberrant splicing of the human tyrosine hydroxylase gene in a child with a severe extrapyramidal movement disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of purified beef adrenal tyrosine hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection by dopamine agonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modest neuropsychological deficits caused by reduced noradrenaline metabolism in mice heterozygous for a mutated tyrosine hydroxylase gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apomorphine in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The physiological disposition of H3-epinephrine and its metabolite metanephrine

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TYROSINE HYDROXYLASE. THE INITIAL STEP IN NOREPINEPHRINE BIOSYNTHESIS

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relevance of iron in the pathogenesis of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted Disruption of the Tyrosine Hydroxylase Locus Results in Severe Catecholamine Depletion and Perinatal Lethality in Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional and high level expression of human dopamine beta-hydroxylase in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic TVP-1012 (rasagiline) dose--activity response of monoamine oxidases A and B in the brain of the common marmoset

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemistry of postmortem brains in Parkinson's disease: historical overview and future prospects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetics of dopa-responsive dystonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A point mutation in the tyrosine hydroxylase gene associated with Segawa's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Further experimental studies on the catecholamine metabolism in extrapyramidal diseases (Parkinson and chorea syndromes)].

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral and cognitive signs: delineating the significance of impaired catecholamine metabolism in Parkinson's disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and distribution of two isoforms of tyrosine hydroxylase in macaque monkey brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in multiple tyrosine hydroxylase mRNAs in the substantia nigra, locus coeruleus and adrenal gland of MPTP-treated parkinsonian monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential sources of increased iron in the substantia nigra of parkinsonian patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homospecific activity (activity per enzyme protein) of tyrosine hydroxylase increases in parkinsonian brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A RAPID AND SIMPLE RADIOASSAY FOR TYROSINE HYDROXYLASE ACTIVITY

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the 5' region of the human tyrosine hydroxylase gene: combinatorial patterns of exon splicing generate multiple regulated tyrosine hydroxylase isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of tyrosine hyroxylase gene transcription in ventral midbrain by glial cell line-derived neurotrophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of cDNA and chromosomal assignment of the gene for human phenylethanolamine N-methyltransferase, the enzyme for epinephrine biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1‐Benzyl‐1,2,3,4‐Tetrahydroisoquinoline as a Parkinsonism‐Inducing Agent: A Novel Endogenous Amine in Mouse Brain and Parkinsonian CSF

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New species of human tyrosine hydroxylase mRNA are produced in variable amounts in adrenal medulla and are overexpressed in progressive supranuclear palsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and molecular mechanisms of Parkinson's disease: neurotoxins, causative genes, and inflammatory cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-dopa therapy in Parkinson's disease: a critical review of nine years' experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoamine oxidase and catecholamine metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurochemistry of Parkinson's disease: effect of L-dopa therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene therapy for Parkinson's disease: from non-human primates to humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photometric assay of dopamine- -hydroxylase activity in human blood.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of mouse and human GTP cyclohydrolase I genes. Mutations in patients with GTP cyclohydrolase I deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereochemistry of biopterin cofactor and facile methods for the determination of the stereochemistry of a biologically active 5,6,7,8-tetrahydropterin

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the alternative promoters that regulate tissue-specific expression of human aromatic L-amino acid decarboxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods for gene transfer to the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DL-3,4-threo-DOPS in Parkinson's disease: effects on orthostatic hypotension and dizziness

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is selegiline neuroprotective in Parkinson's disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ELUCIDATION OF THE RATE-LIMITING STEP IN NOREPINEPHRINE BIOSYNTHESIS IN THE PERFUSED GUINEA-PIG HEART

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine hydroxylase: human isoforms, structure and regulation in physiology and pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic

1 reference

https://pubmed.ncbi.nlm.nih.gov/27491309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00702-016-1596-4

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

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